Hi, a friend of mine got a prescription for Ritalin recently, 20mg once per day, and has been snorting the daily dose instead of eating it. He says the first few days were great, about an hour of intense 'buzz,' but after about a week it lost its effect, maybe helping focus a bit but no noticeable change in state. His question is, if he were to eat his dose for a few days, would tolerance go down due to methylphenidate's low oral bioavailability? And if so, how long he would have to eat it before effects would return when snorted. He also takes 400mg a day chelated magnesium, 200 in morning and 200 at night, as this has been reported to help with tolerance.
