Phenethylamines Low Dose Mescaline

[Esperighanto]

What I meant is that low dose mescaline shares some similarities with MDMA (pro social empathic openness, good mood, stimulation) that it can be used in similar way.
Ofc it's still different experience.

Oh I certainly see the parallels between mescaline and MDMA that you're referring to, I just personally view 2C-B as the training drug for both MDMA and mescaline but I could see people finding 2C-B more challenging. This whole concept of pharmacological training wheels is quite a neat one, I'll be rolling these ideas around for a while.

 

[doubledog]

You are likely responding to Leprechaun's post about training

Personally, I see 2C-B as something like younger brother of mescaline, quite similar, but lighter, easier.

 

[Esperighanto]

You are likely responding to Leprechaun's post about training

Oh yes, sorry about that!

Personally, I see 2C-B as something like younger brother of mescaline, quite similar, but lighter, easier.

I often have described 2C-B as a sort of "fast-forward mescaline" experience. It is certainly capable of pushing you to the classic DMT-breakthrough style experience though, I eyeballed a 75-100mg line of it back when my fiance and I were daily users of 2C-B for 6-8 week periods during some seriously cold and dismal winters in Portland Maine during covid. We were about to go get sushi with a homie, the same exact setting of when I drank that vial of LSD, the same friend and the same intention of immediately leaving to the sushi buffet. I did that line, vomitted exactly once, curled up on my side and passed out into slithering, downwards flowing snakeskin patterns with scale shapes that self-transformed. Lots of blues, darker browns, a unique swathe of colors I now associate with 2C-B, DOB, 25B-NBOH and 25B-NBOMe, it seems to be a 2,5-dimethoxy-4-bromo thing I guess? Idrk, I'll have to explore this whole SAR further to have a more complete take on that.

The classic "trip has a lesson to teach you" thing just showed me how much joy and love my life would have if I dedicated as much time as I could to the pursuits of art and music. It wasn't wrong, tbh.

 

[Leprechaun]

For being somebody who didn't take to cannabis, ayahuasca, or even mushrooms (relative to pure 4-subbed tryptamines), the coadministration of methamphetamine and mescaline is a fascinating move from Sasha, it seems he always leans in favor of absolute cognitive clarity when possible. Where was this experience report written? I'd love to give it a read.

I've been trying to find adequate imagery to abstract this concept of the intensity of an experience negatively correlating with the ease of integration, the reason I tend to prefer guiding people on either super lightweight or super heavy duty trips is because I know how to approach this from either the low-dose or high-dose end of things, but locating where in the middling regions this lies can be tricky sometimes. One of the major ways I've worked to grow as someone who guides experiences is learning to intentionally apply things to upmodulate or downmodulate the intensity of an experience to the ideal place for whatever the session's goals are.

Are you saying people perspectivize MDMA as the training drug towards the more psychically deep 2C-B/mescaline? I have had MDMA induce straight up suicidality that I could not easily combat, but I've never had a single psychedelic do me that way.

The experience was written in one of the pharmacology notebooks. Not exactly sure which one but it was around 1985 1986.

In the pharmacology notebooks you’ll notice right near the end of books around 1992 Sasha was consuming a lot of LSD which is a very, I guess cerebral analytical experience, however he did actually prefer to use the phenethylamines a lot more in the 80s so I’m not sure what happened there.

In the 80s, Sasha and Anne were using a lot and I mean a lot of psychedelics, one every week at minimum so it’s quite a stretch from the average user in my experience.

Regarding MDMA as a trainer, I believe this is purely because it is one a short acting experience and two. It is very friendly and at the effective dose unlikely to produce any unwanted panic reactions not that it never can but it is very unlikely compared to the classic psychedelics.

Also, the classic psychedelics need you to be aware of a sense of letting go without which if you try to find the experience it can turn dark and problematic very quick.

 

[Ismene2]

Low dose is very friendly as long as you take it anally. ANY dose of mescaline orally causes severe nausea and you've got the problem of choking down horrendous gag inducing cactus snot - simething so bad it makes ayahuasca taste like fine wine.

 

[tryptakid]

I'm wondering if anyone has experience with lower dose mescaline, as I am under a theory that it may be a worthy alternative to MDXX compounds. Thinking about 150 mg, give or take

It seems typically 2cb or similar are recommended for that role, but I think from reading about how mescaline has a lot of empathy, warmth, and euphoria, that lower doses might be a decent replacement, assuming it doesnt cause that uncomfortable "half in, half out" sensation that can come from psychedelic doses that arent quite high enough.

Any thoughts?

I've played around with low dose mescaline - it's a nice micro/mezzodose. Definitely stimulating and clear-headed, moreso than an LSD micro/mezzo can be. Good for social situations, but can lead to nausea occasionally.

 

[Leprechaun]

Low dose is very friendly as long as you take it anally. ANY dose of mescaline orally causes severe nausea and you've got the problem of choking down horrendous gag inducing cactus snot - simething so bad it makes ayahuasca taste like fine wine.

I recently had 110mg of Mescaline with no nausea.

There seem to be people who never react to the nausea … I welcomely drink 1 litre of Cactus tea without any nausea…

 

[Ismene2]

I always spent hours/days preparing cactus tea then took the first sip, gipped, put the cup down with a long trail of snot dangling from my chin to the cup, and could never swallow anymore without gipping it back up.

I did manage to squirt some up my bunghole several times.