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Opioids Loperamide (Immodium) Megathread: We have now lost at least 2 of our own from Lope

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Next time try it with 1000mg cimitidine and white grapefruit juice. I sometimes even get a slight buzz and it definitely took away all my withdrawal. The problem is now I have to get off the lope. The withdrawal is as bad or maybe a little worse than methadone. Im going to try tappering 1 pill a day.
 
eh i will try, i am experienced with the whole cimetidine thing, and usually it makes opiate effects stronger, but if there not there at all in the first place, theres not much to make stronger. but ill give it a try


also for those worried about constipation, i doubt it is much worse than other opiates. if you take it daily long term, there may be problems. however i took about 180mg when i was withdrawing hardcore, and i still blasted diarrhea out my ass like i was trying to launch to the moon.
 
RedRum OG said:
eh i will try, i am experienced with the whole cimetidine thing, and usually it makes opiate effects stronger, but if there not there at all in the first place, theres not much to make stronger. but ill give it a try


also for those worried about constipation, i doubt it is much worse than other opiates. if you take it daily long term, there may be problems. however i took about 180mg when i was withdrawing hardcore, and i still blasted diarrhea out my ass like i was trying to launch to the moon.
Click to expand...


also It takes up to 3 hours to kick in, its usually 1 1/2 - 2 hours for me. You probably already knew that but just making sure.
 
I'd love to hear from anyone who is going through what I am or has already been through it. loperamide was a godsend at one time but now its a prison.I could really use any of your stories or advice about how you got off it. Im doing a tapper but my tolerance has went up and its hard not to take a higher dose. I hope I hear from someone, sometimes I feel so alone in this because its not something alot of people understand.
 
this is my first post but i wanted to say that i understand that alone feeling. i was clean for 4 yrs, then relapsed and picked back up shooting IV H.( prob a bundle of NYC good D at that) so i still have that label as the "sober guy"..always get the shitty feelings out of your head even if there to a peice of paper bro, keeping it in is a sucky feeling feel free to message me to talk..
i start my taper tonight.. gonna pop 15 lope b4 bed so i dont wake up in WD. and start at 15 x aday tomm, if that holds me i will decrease the amount of pills by 1-2 each dosing till im off.
wish me luck bro
 
I wish you the best. It takes alot of courage to face your demons. I am so glad to hear you are trying. Please let me know how you are doing. Im still tappering and am determined to beat this and it was great encouragment to hear from you. Thanks. :)
 
I've taken 12 lope so far this evening... considering a few more. It does work no doubts there...I've battled oxys, lorcets, vicodin etc for the last 3 years. And numerous times loperimide has stopped my writhing pain, rocket ass, and body aches in its tracks. 50 mg and above doses...of course I still crave like hell but its better than the sleepless horrid pain. Day 2 without my pills and I feel like death. Its been about 50 days since the last time I was out :(. I've been consuming 50-120 mg in a 12 hour period ish. Fuck I'm tired of these mfs running my life!:sus:8)
 
I hear you on that! So im a little confused, how long have you been taking lope? Are you only using it in between your reg doc? Either way I wish you the best and hope you can break free.
 
Hey y'all,

Six years of being on opiates, four of those being on 30mg roxicodones 8x a day and 40mg oxycontins 2x a day.

I've been tapering down - on paper, I'm down to three 20mg roxis and two 40mg Oxys; I don't really keep track but I DO DEFINITELY know I've tapered way down.

I've been wanting to kick this shit for a long time, and my head and mentality is definitely in the game, and I want/need to come off by the 26th of this month. Long story short, a practitioner at a PCP practice has been helping me taper down, I never signed any sort of pain contract with them, never got UA'd, and since the taper has restarted my insomnia, I've taken a few benzo's here and there in addition to my MMJ (which she knows I am), and last week the sprang a UA on me and despite the fact that I never signed anything with them and they can't TECHNICALLY 'hold it against me', the doc can certainly decide to cut me off, which I have a feeling he'll do on the 26th.

So, I'd really rather not chance it, and try doing a rapid taper to get me off ASAP.

Realistically, can this be done utilizing loperamide? I have, like, 8-10 40mg Oxys left (I've been cutting them in half), and about 20-35 20mg roxis left (which I haven't touched since thurs; again, just been cutting my Oxys up and either swallowing or chewing the halves/quarters), and I'm wondering, what's the best way to go about this??

Can loperamide be used in addition to a taper? Should I simply go for the loperamide, and only use maybe one or two of my opiate pills in the morning and before I go to bed?

Asinine and redundant questions, I'm sure, but, there's a LOT of posts here, and I'm asking in relation to my specific meds, dosages, and time allotted.

Any and all advice is so very greatly appreciated; withdrawal is terrifying and something I feel I'd rather die than experience again <3
 
I used 120mg a day to come off 120mg a day methadone. I switched completely to lope and had no withdrawal. If you do this though, I highly recommend you immediately start tappering the lope and also your dose probably doesn't neeed to be a high as mine. It definitely gets rid of withdrawal but my problem was I stayed on the lope and even increased my dose so now I am try to tapper from a ab much higher starting point. Ive been taking lope exclusively now for about 4 months. I now am down to 95mg twice a day. I also take it with white grapefruit juice and cimitedine, it seems to help it work better for me. I wish the best for you and I hope you will post your progress if you decided to do this,
 
Mercy that's a lot of loperamide...I've been combing through the posts here, trying to find a definitive "yes, you should completely cut out your opiate meds" or "no, you can use. Both, but sparingly", as I'm soooo nervous about going about this in a way that's only going to harm/worsen the withdrawals...and I definitely don't want to become dependent on the loperamide, either, I wonder how fast I can start cutting back on that...a week, until my opiate meds clear my system? Idk...hah, scary stuff, to be honest.

I think I'm going to keep a journal of my little taper journey/experiment...hope this works!
 
Alright, upon reading through most of this thread i've decided to perform an experiment not yet performed before on this thread. This morning (Over 12 hours ago) I took 40mg of Omeprazole for chronic heartburn. I am aware that Omeprazole is a P-gp inhibitor and effectively widens the blood brain barrier. 30 minutes ago for good measure i took another 40mg of Omeprazole and 10 mg of loperamide. I am hoping that the widening of the blood barrier on top of a glass of vodka will give me some sort of desired opiate effect. I will keep you guys posted

Edit 1 +2 hrs after initial dosing: No noticeable opiate effects. I plan on taking another 14mg of loperamide and 30mg codeine

Edit 2 +4 hrs after initial dosingL Noticeable effects. More than likely a combination of the extra 60mg of codeine i took and half a bottle of vodka polished off in between reports.

Edit 3 +5 Jours after initial dosage. Heavy opiate high taking place and i took an extra 60 mg of codeine (oral). Feeling very nauseous, Maybe the loperamide and the cheap vodka were bad choices.

Edit 4 +1 day after dosage. The hours following the previous edit were very unpleasant. While the opiate buzz remained i became sick. Heavily nauseous and vomited for the following 8 hours. It was difficult to eat and keep down fluids until maybe 10 hours after the previous edit. I believe it was due to the combination of codeine (Which also had acetaminophen 2g) and vodka which took a toll on my liver. I don't feel loperamide has much potential however further testing should probably been done excluding variables such as mixing with other opiates and alcohol.
 
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Please be careful with taking it with alcohol, there was a bluelighter a few years ago that died from using lope and alcohol. I hope you post to let everyone know your ok. Please be careful.
 
So I decided to try doing a CAE and the nasal route, since there is an idea floating around out there that this will help the lope cross the BBB.

The CAE was simple, just followed the directions posted earlier in this thread (I can't remember the poster's name, but thank you) and sure enough I ended up with some material I could easily grind down into powder. I used 15 pills, or 30mg. Ended up with ~2g, or a little less than a tsp., of powder substance. Too much to suck up all at once, IMO, esp. since the last poster that tried this suffered burning nasal passages/sinuses.

Decided to start off slow and easy so I just put enough powder, was probably the equivalent of 2 tablets, down on my plate and took a small bump. No problem. Went for a bit more, but stopped there just in case, and am I glad I did. Although the powder went down (up?) smooth, within 10 minutes my nasal passage began to burn. Very unpleasant. Not to mention the drip is thoroughly disgusting, and now that side of my nose is plugged up. All from a very small amt., maybe half of what I initially put down. I'm just not going to put the rest of that shit up my nose.

Thinking of drinking this big glass of grapefruit juice and parachuting the rest. Wonder if it would still cross the BBB (or be prevented from crossing right back, whatever, I get it) since I already did the work of the CAE.

Would love to find a way to get somewhat the same benefits of an opiate high with this stuff, seeing as how its legal and easy to get.
 
Loperamide has always helped me in terms of physical wds. Like it helps kill a lot of pain and general wds symptoms.

The problem is, I've NEVER been able to stay on loperamide for more than a week or 2.

I wind up getting so BLOATED, I get these terrible headaches, I retain so much water / shit / toxins and I believe these
toxins build up in my body. All I know is it bloats me so badly I feel like an overflated balloon.

If I had to stay on that shit for a month or 2, I'd lose my mind. Even when I was drinking lots of water and metamucil,
nothing removed the terrible bloat and symptoms that came a long with it.

I want to try it again to come off .25mg of sub. This is the lowest I've ever been on sub, so I'm thinking the lope may
help me out. The problem is sub is a POWERFUL antidepressant, so I'm likely to go into a severe depression even if the
lope quells physical wds. Guess I won't really know till I try.
 
I am new to the forum, just thought I would give my story and offer some insight into myself and maybe gain some needed information. I have been addicted to opiates/opiods for about 2.5 years started off with hydros then went to oxys then to ms contin 100s tolerance was up to ms contin 100 2x per day and still could work function. Finally my supplier dried up and had to withdrawal. Did the methadone route for 2 months was 60 miles away from clinic and couldnt afford it anymore. So I c/t off of 60mg methadone. It has been like hell on earth. Did the c/t about 15 days ago and tried loperamide to relieve the withdrawal symptoms. The most I have been clean was 5 days for the last 2.5 years.Took 30mg and it did seem to help with the physical part of most of the w/d . I did all the research on cimetidine,quinidine,etc for the bbb issue and all the flaming about how it was all bs, but I only took just loperamide. I did more research and found this http://www.ncbi.nlm.nih.gov/pubmed/7438696 basically around 50 percent of people who took 60mg of lope identified it as dope so imo their is no question about it being a great aid for physical and some mental withdrawal maybe somewhat like codeine. Have had very little issue with bm as I take stool softners anyway. Well since my c/t off methadone, I have acquired some hydros occasionally over the last 5 days, and have been taking them off and on never over 25mg a day but it holds me, and there has been a couple of days that I didnt have any at all. I cant handle the mental aspect of withdrawal, i dont know what life is without opiates/opiods. I am going to the store tonight and get more loperamide, no it doesnt feel like an oxy or anything but it at least will dull my pain for a while. I also have bali kratom on the way friday and I am resolved that I think I will be addicted to something opiate like forever. I dont want to be, but life just sucks without them, I dont know who I am or who I was before I started taking them. My fiance thinks I am completely clean and doesnt understand addiction at all nor ever will. I wont take the loperamide for long, just until my kratom arrives, then after my 4 ounces is gone at 5G 3x a day I will go right back on the lope again for a few days and start the whole bs cycle of opies,kratom,lope again. I guess my resolve isnt strong enough to get clean. To those who are addicted to loperamide or any opiate/opiod, its all real and true, I feel for you and I hope that someone here can help me get clean, I dont feel like I can. I have no insurance, dont want to do the methadone route again, nor the suboxone one.
 
Ive now taperd down to 70mg×2 a day. Im not feeling the greatest but im determined to keep going, I've also stopped using the cimitedine but still take with w grapefruit juice.
 
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