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Opioids Loperamide (Immodium) Megathread: We have now lost at least 2 of our own from Lope

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It's been a month since swim stopped Percocets. Today tried loperamide dissolved in warm water with a Rantadine and Omeprazole. Swim let it sit an hour hoping allot of what the rantadine or omeprazole needed to do to the loperamide would be taking effect before injestion. who knows...but an hour after swim drank it swim felt the same opiate effects of tramadol.
 
So taking ranitidine and omeprazole (ostensibly at the therapeutic dose ie 10mg ranitidine and 30mg omeprazole) along with (say, 30-40mg?) loperamide works to give an opiate high?

And the black pepper method. Can I have more specifics please? Like how much is a "handful" and how long must the black pepper be ingested before the loperamide?
 
First off thanks to BL this site has saved my life many times. I've been on loperimide for 9 months ending daily dose 80to 100 mgs with a start dose in the begining of 50 to 60 mgs I took lope 2 days ago and my first dose of suboxone I've had small PW bad diarea runny nose eyes water headache from hell but all has been manageable just took 2 mgs of sub for me lope has been great finally freedom fom scamming for 24 hrs at a time but now I'm ready to be off all of it (I know we've all said it....)I started lope to ccome off methadone 30 mgs and perocet andnucynta heavy daily use it made the transition painlessly I am an addict so finding the maintenance value of anything is in my nature. At any rate wish me luck!
 
I have a script of pantoprazole for heatburn, would this work to allow loperamide to be active?
I've been fairly interested in it, what is the high like compared to other opiates?
As well how much pantoprazole would I have to take?
 
My god ive heard it all now. People taking medicine that keeps you from shitting to get a buzz. Unbelievable!!! Tagamet helps to potenate opioids and opiates. Generic is cimetidine. Try it it works. Take 400mg an hour before taking your opiate
 
I have coming cold turkey off 120mg of methadone and am using 120mg of loperamide a day. I have no withdraw symptoms but im very concerned about the effects this may have on my body. Has anyone else used it like this successfully? I take it with cimitidine and grapefruit juice. It is truly amazing.
 
About 32 hrs ago took about 16mg of loperamide and then again a few hours later(32mg total) as an anti-diarrheal.
Surprised how mild my withdrawals have been. Was able to sleep.
Only feel like I have a mild flu. Mild restless legs, sensitivity to pain, and overall uncomfortable. Slightly emotional.
My tolerance was fairly mild from short term use , but I was to the point that I needed 20mg oxycodone to feel normal for about 8 hours.
If I feel the need to take more, I will try with doses of 4mg or so. I don't want to become constipated or dependant on loperamide, I just don't want to be miserable during withdrawal.
 
Huh. When I needed 7-8g kratom to feel normal I'd have to take something like 30-40 of the 2mg lope pills to squash WD. Once time I took 50 or 60 of them, maybe more I don't remember, and seemed like I got the overflow effect allowing some to stay across the BBB (it crosses but essentially is immediately sent back out by something). I've read that you can take enough where not all of it is booted out. Seems so. No euphoria or anything. I got pretty itchy and my body felt a little more than not in WD. Had a job interview soon after so I started taking/redosing DPH to counter the itch. Ended up with like 200-300mg in my system before itchies became manageable -- made for an interesting interview. I wouldn't call the 'excessive lope' thing a high...

Corazon, with a lower tolerance/dependence like that you could probably taper your self down with the lope easily. That's what I'd do... I doubt anyone would want to continue taking the same dose/increase dose to maintain a dependency. Though some do. I find importing kilos of top quality kratom from indonesia (verrrrrrry cheap - 1/3 the price buying domestic kilos) is much better for maintenance. I dunno how much bulk lope costs but even if cheap it's not ideal. I'm happy to personally know my kratom supplier. It can be a shady business with lots of overpriced stuff. Any packaged product from a smokeshop is an insane ripoff.
 
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Huh. When I needed 7-8g kratom to feel normal I'd have to take something like 30-40 of the 2mg lope pills to squash WD. Once time I took 50 or 60 of them, maybe more I don't remember, and seemed like I got the overflow effect allowing some to stay across the BBB (it crosses but essentially is immediately sent back out by something). I've read that you can take enough where not all of it is booted out. Seems so. No euphoria or anything. I got pretty itchy and my body felt a little more than not in WD. Had a job interview soon after so I started taking/redosing DPH to counter the itch. Ended up with like 200-300mg in my system before itchies became manageable -- made for an interesting interview. I wouldn't call the 'excessive lope' thing a high...

Corazon, with a lower tolerance/dependence like that you could probably taper your self down with the lope easily. That's what I'd do... I doubt anyone would want to continue taking the same dose/increase dose to maintain a dependency. Though some do. I find importing kilos of top quality kratom from indonesia (verrrrrrry cheap - 1/3 the price buying domestic kilos) is much better for maintenance. I dunno how much bulk lope costs but even if cheap it's not ideal. I'm happy to personally know my kratom supplier. It can be a shady business with lots of overpriced stuff. Any packaged product from a smokeshop is an insane ripoff.

Thanks for the advice. I've been curious about kratom, but for now I'm just going wait until I am prescribed pain medicine again. I have a genetic disorder with bullet-proof medical records, and MRIs, CTs etc... My spine has been causing me severe pain. I had a meeting with a pain management doctor last Friday and was 100% expecting(and calculating the "hold-over" percocets my primary doctor had rx'd ) to be put back on pain management (I had previously came off of pm by my own choice 2 years ago).

Unfortunately lol I ran into a nightmare local doctor in smalltown USA. He did not have an accurate knowledge of my condition, and his personal theory on pain management seemed to be that "if you can dress yourself, you don't need pain medicine" (I personally would like to have a job, upkeep my house and my yard, and be able to integrate into society without debilitating pain, but that's just radical me :) ).

I took 12 mg loperamide last night after after normal bm, and that's it. Back in the medicine cabinet. I've got extra loperamide if I ever need it again, hopefully lasts me several years. This did benefit me, as I could sleep, and was not dehydrated. If my spine wasn't killing me, I would be up and about at this point (Day 4 mild withdrawals).
 
i have been taking 20mg of loperamide a day for 9 days now to help combat withdrawal, how long do i have to use lope before i experience its withdrawal?
 
^Half life is about 10 hours, so probably start feeling it around 24 hours and 36-48 for full w/d symptoms.
 
Hi all. I decided to test out loperamide because I get drug tested and I am actively looking for ways to change my mindspace without having a positive drug test. (Sobriety is all very well, but I can't be having with too much of it.) Some background on me: I am a female of young middle age and average weight. I have never been addicted to an opiate (my prescription pill addictions were Xanax and Fiorcet before I went to rehab and did away with them.) I have an extensive drug background (been doing drugs since 1998, mostly illegal psychedelics, and I have been a hardcore user of many.) However I must now work within my limitations - I can use/abuse meds I am prescribed, or I can drink but not to excess, or I can use/abuse OTC meds that are available to me. I do smoke a little weed now and then if I know I'm not going to be drug tested anytime soon, but again, not to excess.

Tonight's experiment consists of 10 mgs loperamide, a 10 ounce bottle of grapefruit juice, 40 mgs Prilosec (consumed 30 minutes prior to taking the loperamide.) I will allow myself to increase the dose to 20 mgs, but only after I wait and see how I feel. I'm concerned because I have a social outing tonight and if I don't drink the sangria it will look suspicious. However, I'll keep it to a minimum.

On a daily basis I take: 5 mgs Zyprexa, 200 mgs Topamax, and Neurontin (gabapentin) as needed. I really hope this works because gabapentin is the only other thing I can use/abuse to feel some relief from this grind.
 
Felt nothing at 10 mgs. Upped the total dose to 14 mgs and then 20 mgs. At 20 I noticed a warm tingling in my legs followed by opiate-like itching. I feel more or less sober though...a little bit lightheaded and increasingly tired. I'm going to call it quits for now and try again next weekend, this time starting with 20 mgs.

One interesting thing to note is that my anxiety is much diminished. Perhaps I can use this as a backup when I run out of gabapentin.
 
I tested the loperamide on Sunday night. Today is Wednesday and I am going to try again, hope that enough time has passed so that I don't get a tolerance effect. I don't have grapefruit juice handy to use this time. I might go to the store and buy some but not for a little while. I just took 20 mgs of loperamide. I'm having a crappy day which is why I decided to try this. Those pills are chalky and really hard for me to swallow. If nothing comes of this I might just leave it alone. I'm not going to take 50 pills just to get high.
 
I ate something (noodles with butter) and, based on things I've been reading in the opiate potentiation megathread, took a big swallow of promethazine DM. Blehh, tastes nasty. I then took 10 mgs more bringing the total to 30 mgs. I feel a bit spacey but that could just be the cough medicine. But I've heard loperamide takes a long time to kick in. So still waiting!
 
Hi everybody. I (unfortunately) have a lot of experience with opiates of all kinds and thought I'd chime in on the loperamide (immodium) issue. I haven't read this entire thread so forgive me if this has been said before. Please keep in mind that individual results may vary.

On the record: I will tell you that immodium doesn't do a damn thing. Getting high off diarrhea medicine is the most ridiculous thing I've ever heard!!

Off the record: I will tell you to just add Tonic Water. Just look for any tonic water that contains Quinine (should say it right on the front of the label). The tonic water is usually sold by the liter, one liter usually costs $1.00 (US). The Quinine in the tw helps the lope cross the BBB. The following method works best for people who are heavy opiate users and need to keep functioning when the good stuff runs out. Get yourself a couple bottles of loperamide and 5-10 liters of tonic water. Also, pick up a bottle of diphenhydramine (Benadryl). (If you suffer from legitimate pain issues like I do, get a bottle of advil or acetaminophen also, this will help with inflammation based pain).

***Proceed with caution and go SLOW. You can always take more if you need to, but once you take too much, you can't take less. I'm not a doctor and this is not medical advice.***

Initial Dose: This is your first dose of loperamide after the last dose of your drug of choice runs out. The amount of loperamide taken will be different for everyone, depending on your level of tolerance. (I was taking between 200mg -300mg of oxy everyday). First thing you do: Start drinking the tonic water. Drink about 1/4 of a liter of TW before you take the lope. Then take 20mg-30mg of loperamide (10-15 pills, 2mg each). Then drink another 1/4 liter of tonic water.

T+ 30mins: Take 800mg of ibuprofen OR 1000mg of acetaminophen (either/or, NOT both). This helps with inflammation. Also, if you have been taking large amounts of vicodin or percocet, your body has grown accustom to acetaminophen, so adding this to your WD strategy can help. I usually wash these down with caffeine (soft drink or coffee) just because I always take my oxy with caffeine. Caffeine goes good with opiates during the day (then stop drinking caffeine at night so you can fall asleep later). Continue sipping on TW occasionally.

T+ 1 hour: Drink another 1/4 liter of TW (you can spread this out, sipping it over time instead of chugging it). Take another 20mg-30mg of loperamide (whatever amount you took an hour ago). Then drink another 1/4 liter of TW. (You should be finishing your first liter of TW around this time).

T+ 1:30 - Take 800mg of ibuprofen OR 1000mg of acetaminophen. Start 2nd bottle of TW, sipping TW occasionally.

T+ 2 hours: You should be feeling a little better by now, and some people will be feeling GREAT!! by now. Depends on individual chemistry. Drink some TW, then take 16mg-26mg of loperamide (8-13 pills, 2mg each). Then drink more TW. (From this point forward, it's not necessary to drink 1/4 liter every time. The important thing is to keep drinking it gradually over time).

T+ 2:30 - Take 600mg of ibuprofen OR 500mg of acetaminophen.

T+ 3 hours: Drink more tw! Take another 16mg-26mg of loperamide. Drink more tw!

T+ 3:30 - Take 600mg of ibuprofen OR 500mg of acetaminophen.

T+ 4 Hours: Drink more tw. Take 16mg-26mg of loperamide. Drink more tw.

T+ 4:30 - Take 600mg of ibuprofen OR 500mg of acetaminophen.

T+ 5 hours: Take 50mg of Diphenhydramine/Benadryl (2 pills, 25mg each). Continue sipping tw.

T+ 6 hours: Drink some tw. Take 16mg-26mg of loperamide. Drink more tw.

T+ 6:30 - Take 600mg of ibuprofen OR 500mg of acetaminophen. Continue sipping tw.

T+ 7 hours: Take 50mg of diphenhydramine.

T+ 8 hours: Drink tw. Take 12mg-22mg of loperamide. Drink tw.

T+ 8:30 - 600mg of Ibuprofen OR 500mg of acetaminophen.

T+ 9 hours: Take 50mg of diphenhydramine

T+ 10 hours: Drink tw. Take 10mg-20mg of loperamide. Drink tw.

*That's it! By now you should be feeling anywhere from A LOT better, to "normal", to holy **** I feel GREAT!!!

**As Always with WD's, The First Day is the worst day. It takes awhile (sometimes up to 24 hours) for the TW and Lope to really start working. But once it does, you will feel a lot better. By day 2, there should be no wd's at all.

***From this point on, just continue sipping tw all day and taking 10mg-20mg of Lope every 2 hours (along with 600mg or 500mg of Ibuprofen/Acetaminophen if you want). Then, at night, start taking the benadryl every couple hours until you fall asleep. This combo should give you a good "nod" most nights. After the first day or two, I usually on average drink 1 -2 liters of tonic water per day; and take about 40 - 60 lopes per day (4-6 pills every 2 hours). Buy the generic loperamide, they are really cheap and work just as good as brand name Immodium.

***Once again, this method is for moderate to heavy opiate users. If you are opiate naive and don't have a high tolerance, then DO NOT use this method. If you are looking to "get high" DO NOT use this method. Like I said, getting high off diarrhea medicine is the most ridiculous thing I've ever heard! :-)

Hope this helps someone. Peace.
 
So if I have like a pint of grapefruit juice and/or a handful or regular black pepper and then half an hour later take 30 or so 2mg generic loperamide pills, I'll can an opiate-like high?
Would all that lope (the active ingredient in immodium) not cause severe, chronic, constipation? If not cause an blockage in the bowel?
 
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