Everything above is great info!!
dont forget the whole competing nutrients across the blood brain barrier idea.
Plain and simple, after MDMA, getting your serotonin levels up is the ONLY concern. So taking 5-HTP ONLY is the thing to do. You dont want it competing with other less crucial nutrients, esp ones that u dont want around anyway; e.g L-Tyrosine.
I do agree that the whole pre-load notion is probably an exaggeration for the reasons phase-dancer said, but post-load, 5-HTP imo has no equal.
Lets face it, serotonin levels were never meant to be altered in the way MDMA effects them. The body will do absolutely everything possible to return them to normal, as its such an unnatural state. As tryptophan is relatively rare in the diet and the hydroxylase enzyme (converts tryp -> 5-HTP) is rather slow/rate-limiting, giving urself 5-HTP will have it crossing the BBB, and the decarboxylase enzyme acting on it almost immediately, getting those serotonin levels up again...FAST. Or at least a lot faster than otherwise.
SSRIs after a roll i do think r the answer. And then start HTP a fair bit after that; maybe 6 hours. u dont want serotonin syndrome; but if ur stocks r empty this is unlikely, provided an ordinary dose of HTP.
Too many people i know will take speed after MDMA. I do it on occasion and i agree this has gotta be bad news.
Whilst not categorically proven, a strong SSRI then a line of amphetamine may be far less of a problem.
And i agree, that when i did have access to SSRIs and used them that scattered feeling was unapparent; which is esp apparent taking speed after a night on the pills.
As for other things to take after, if dopamine is a problem then surely GHB is very good. And t makes for a most pleasurable and fun comedown too. Plus the ability to induce safe sleep if u really cannot deal with staying up anymore.
Shame its almost impossible to get
[This message has been edited by Biscuit (edited 23 April 2001).]