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Dissociatives [Ketamine Subthread] Dosage and Methods of Administration

Dont quote me on this, but if your snorting it, i think you would k-hole long before the overdose threshold. I'm sure i read somewhere that when it was used in humans as an anaesthic they would IV over a gram at a time?
 
Yeah, the more you do, the more damage will be done...

I don't know how much your actually planning on doing, but if you've done it before and had a good time, then just take a similar ammount, increasing the dosage if you feel that its right.
 
To OD from ketamine you would have to surpass the level in which you would be knocked out cold from it because of its anaesthetic properties.
As fastandbulbous stated, it would have to be intentional.

For me, once I reach the hole (if its strong) im in a way paralyzed and am unable to really move so its all about the initial dose (if you're working with high doses)

For dosing via insufflation you should go by:
1 mg / lb (100 - 250 mg usually)
Link

As for IM you should go by:
.75 mg / lb (60 - 125 mg usually)
Link

The question you asked was a bit vague, as it really depends on the user.
I suggest clicking on those links that i posted above and searching through the rest of the ketamine vault on erowid.org to make sure you know what you're doing.
Be safe, have fun ;)
 
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^Sorry to bump an old thread,

Put would autoclaving the solution pre-injection be overkill?

I've got some R-Ket coming and I think I may try this, assuming I can get some clean needles and filters.

A few months back I recieved some 500mg ampoules and had a friend help me with IM injection, it was okay, but I think she was injecting half or less than what I had requested for safety reasons. As well as it wasn't the superb Ket I was used to once starting this thread. I now have access to both kinds, and will compare and contrast then add into this thread for general information. I have since learned, however, that the Anaket brand was a ratio between the two isomer's, so I was never doing purely S K. I now have access to two different kinds, the S twice as costly. I opted for the R, just to see.

Will update.

Hey Jamshyd, are you around at all? I'd like your input as well since I value your opinion in these matters (I'm treating a bi-polar II condition with this K, or trying to at least).

<3
 
Some stuff that may or may not answer your questions:

First I crush (glass crusher on a mirror) the grains into a very fine powder.
Then I lay out a couple of small lines (10-20mg or so) and do those 2 (got two nostrils...) at a time.
I've found that doing small lines is a lot more effective than railing big ones.
Definitely more pleasant too.
My nose likes it better too and much more K enters the bloodstream directly instead of dripping down my throat and going the oral route.
I try to snort a bit every 1-3 minutes, but once it's working really well that often becomes a bit problematic.
Time quickly starts to warp and occasionally loop or even run backward.
At that point it's not much of an issue, I just snort some when I think of it or feel like it.
As soon as it's unfolded the way I like it I only do the occasional maintenance dose.
If/when tolerance becomes an issue i.e. I need more than say a gram a night, I take a break of 10-20 days.

I usually sit or stand/walk, always with my eyes open.
In that manner I consciously avoid K-holing as it's not much use to me.
Fun yes but I don't get much else out of it. It does happen but it's rare.

K seems to mess with coordination like alcohol but that's not true, it's more like it slows reactions down so the timing is off. Hence the perceived clumsiness.
Activities that require coordination but not speed are as easy or easier than when sober.
Hatha yoga practice is greatly enhanced, possibly more so than with any other psychedelic. Except that I'm unable to do a headstand on K for the mentioned reason.

Anyway I often keep going like this for 6-10 hours.

I get no lethargy or hangover symptoms, and always feel great afterwards and the next day(s).
After LSD/mushrooms etc I don't like to work or work out the day after. No problem with K.

I'm totally unable to describe the K experience itself.
I can sort of explain about LSD etc but not K.
Weirdness.

I didn't know that snorting bigger lines at time was less effective and more wasteful than snorter more smaller lines.

I always used to just measure like .2 grams and split it in 2 lines and did .1 gram per each nostril and then laid back and always had another .1 gram line ready on the table just incase I needed another boost.

So would it be better to split .1 gram into 2 lines and then another .1 gram into another 2 lines and sniff all 4 lines within 5 ~ 10 minutes so i get less drip?
 
Why oral and rectal administration suck and what you can do to change that.

When taken orally or rectally ketamine is rapidly converted into norketamine in the liver by cytochrome CYP3A4(and somewhat by CYP2B6).
Norketamine is one-third the potency of ketamine although is a much more potent analgesic.

Therefor, administration of a CYP3A4 inhibitor (cimetidine and grape fruit juice) would greatly potentiate the effects of rectal and oral administration.

I'm sure this has been brought up before, but I think people write off oral and rectal admin. too quickly as valid routes of administration. I believe, if taken correctly, both routes offer more depth to the experience.
 
i heard ketamine is in its weakest form when it's just been cooked up.
Is this true?

Also how lonmg does ketamine hold its potency for? Isit ok to store in a drak n dry place?
 
Ketamine is ketamine whether it's liquid in a vial, crystalline or crushed to powder. Other than the different isomers - and assuming no cuts - it's all the same stuff really. K-heads swathe themselves in layers and levels of bullshit that it's really quite impressive. Ket being weaker when freshly cooked is one of those myths, I suspect. Pretty sure ket will last a loooooooong time in a cool, dry place too :)
 
Well put, Shambles.

Some questions about IMing Ketamine.

How frequently would you say is safe to IM Ketamine? Once or twice a week in the same muscle? Obviously anything past that you would want to rotate injection sites. I am just wondering how frequently you would want to circulate muscles, etc.

The truth is, I don't IM very frequently, but I just want to know for practicality's sake when to know not to be IMing any more for a given muscle, etc. With veins you can kind of tell by watching them, feeling them, etc, how easy it is to hit them, all that.
 
where would be the best place to store ketamine powder, if you want to store it for a while 1+ years? I was thinking the FREEZER, is that a good or bad idea? or should I just store in desk drawer somewhere? Ketamine in crystallized form has a good shelf life? should I store it in a sealed container?
 
where would be the best place to store ketamine powder, if you want to store it for a while 1+ years? I was thinking the FREEZER, is that a good or bad idea? or should I just store in desk drawer somewhere? Ketamine in crystallized form has a good shelf life? should I store it in a sealed container?

The biggest concern I've found with keeping K for periods of time is keeping it dry. I had some K in powder form a long while ago and it kept for many months until one day it was left exposed in a bathroom with steam (from a shower, so it wasn't really hot). After that the potency dropped quite substantially and when I used a pinwheel filter to clean it up, I noticed a significant discoloration.

So in the freezer, in an airtight container. Possibly even throw in a few silica packets just for good measure.
 
is there any supplements that would be useful if you are using ketamine on a regular basis.

Surely theres something that will prevent damage to the bladder?
 
is there any supplements that would be useful if you are using ketamine on a regular basis.

Surely theres something that will prevent damage to the bladder?

I was doing some research on this topic a while back and it seems that chronic ketamine users had what looked like exactly the same bladders/kidneys as those who suffered from interstitial cystitis.

Now, there aren't many OTC remedies for this but I've read a little bit about DMSO being used as a treatment of some of the symptoms of interstitial cystitis.

Anyway, simple administration of a corticosteroid or anti-inflammatory agent might help reduce the risk of destruction of the bladder/urinary tract...

I can't post links for some reason, but here is a paper that you can look up that would shed more light on what happens to your bladder if you get too crazy with K:
The destruction of the lower urinary tract by ketamine abuse: a new syndrome?
 
^^^
k, I think i'll just stick to drinking lots and lots of water (4-6 litres a day) just to flush my system out.

Also Ive noticed that my sinuses get blocked to the point where I cant actually snort any more ketamine, is there anything I can do to get rid of this problem?

would snorting water be a good idea just to clear the sinuses out? or vix inhaler or something?
 
any person who snorts a lot of powder should own some type of netty pot or nasal saline flush product. Basically it involves squirting saline water up one nostril and out the other. I used to get sinus infections all the time but ever since I got one type of saline flush system, I don't get them anymore.

personally, I've found that mixing K into solution is the best cure for this problem. You can get 200mg into 1ml of water. common pump sprayers squirt .137ml per squirt. So that works out to 1 squirt = 27mg. 2 squirts into each nostril and you're at ~100mg. the only problem with this is any evaporation leads to crystals forming, and ketamine in solution generally isn't a good idea for storage. Although for a night of using, this can be pretty useful, especially considering you can get pump sprayers that hold 5-10ml (so 1-2 grams).

If you are trying to flush your system, I would be careful. Make sure you keep a steady electrolyte intake (like gatorade).
 
any person who snorts a lot of powder should own some type of netty pot or nasal saline flush product. Basically it involves squirting saline water up one nostril and out the other. I used to get sinus infections all the time but ever since I got one type of saline flush system, I don't get them anymore.

personally, I've found that mixing K into solution is the best cure for this problem. You can get 200mg into 1ml of water. common pump sprayers squirt .137ml per squirt. So that works out to 1 squirt = 27mg. 2 squirts into each nostril and you're at ~100mg. the only problem with this is any evaporation leads to crystals forming, and ketamine in solution generally isn't a good idea for storage. Although for a night of using, this can be pretty useful, especially considering you can get pump sprayers that hold 5-10ml (so 1-2 grams).

If you are trying to flush your system, I would be careful. Make sure you keep a steady electrolyte intake (like gatorade).

k what do you mean by steady electrolyte intake? I dont understand please explain.
 
magnesium, potassium, sodium, sugar + H2O

A simple electrolyte drink can be home-made by using the correct proportions of water, sugar, salt, salt substitute for potassium, and baking soda. However, effective electrolyte replacements should include all electrolytes required by the body, including sodium chloride, potassium, magnesium, and calcium that can be either obtained in a sports drink or a solid electrolyte capsule

I'm not sure of the proportions for a home-made "energy" drink, but I'm sure you could find plenty of info about it online.

It's not necessary to drink electrolyte saturated drinks, but if you're drinking a lot of water it's always good to balance it out with vital nutrients.
 
can i just use a bit of cotton to filter ketamine powder? is 23g 1.5 in syringe ok to use?
 
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