Ketamine salts solubility

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What is the best way to make MDMA in my humble opinion?

Safrole --> The Wacker Oxidation --> The Leuckart *using N-methylammonium formate.*

 

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The Wacker Oxidation Of Terminal Olefins [WOOTO] employs refluxing 1 g palladium chloride (whether of valence I or II or either idk; anyone? I know that PdCl will work, but yields may be higher with PdCl2.) to 100 g safrole (from fractionally distilled essential oil of ripe sassafras tree root bark), CuCl, benzoquinone, an oxygen atmosphere, and methanol as the solvent. Up to 93% yields of this ketone intermediate can be had. Works for safrole, 5-methoxy-safrole (from fractionally distilled nutmeg oil), elemicin and allyl-benzene, all terminal olefins. Thus, there is no need for isomerization of safrole to isosafrole. Also, much less messy than that route. A vacuum distillation apparatus may be employed. Next step is the Leuckart to go from ketone to secondary amine product. Vacuum distilling is necessary for the final step before crystallization: distilling 2-methylaminosafrole aka MDMA aka Ecstasy. Finally, dissolve your oil in dry ether and bubble HCl(g) through it OUTSIDE. Wash with anhydrous, non H20 soluble chemical such as diethyl ether of tetrahydrofuran by suction filtration using a Buchner funnel, and spread out the powder underneath a heat lamp to dry. Dosage: 80 to 120 mg 1x per os. Duration: 4 to 6 hours. Dancing to loud, repetitive music has been shown to increase subjective effects by 700% in rodents. "MDMA remains one of the most popular drugs in the world."--Andrew Weil, "From Chocolate To Morphine."

 

[tregar]

Thanks red22 !

Here is the final ZERO NAUSEA 25g seed (800 seed) morning glory wine, simply decant and drink only what is above the 1/4" layer of particles at the bottom. The wine sits in fridge only a few hours, then all the particles fall to the bottom, and it's ready to use!

The particles at bottom are nauseating to the intestines so only drink the wine above it--zero nausea and a fabulous psychedelic trip. You can also drink this wine with regular LSD for a trip that is WAY BEYOND normal LSD. Way more colorful, way more music enhancing, way more visual and euphoric with divine healing.

This wine can also be used for all your aldehyde experiments like making LSI, super potent, VERY similar to LSD but with a much more natural feel.

 

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Nobody Likes Me!

 

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THE_THINKER
1-cyclohexyl-2-(1-pyrrolidinyl)-1-oxopentane

TINKER_BELL
1-cyclohexyl-2-(1-pyrrolidinyl)-1-oxopropane

 

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The Functional Stimulants:

ANDREX
1-cyclohexyl-1-oxo-2-(2S)-methylaminopropane

HUSKER_DU
1-(4,4-dimethylcyclohexyl)-2-methylaminopropane

ELAINE
1-cyclohexyl-2-(2S)-ethylaminopropane

CHRISTOPHER
N-allyl-1-cyclohexyl-2-aminopropane

 

[AlsoTapered]

BTW a LOT of effort went into compiling this thread. It contains multiple BOOKS as well as hundreds of articles.

⫸STICKY⫷ - Useful neuroscience/pharmacology threads

Neuroanatomy and the Brain Erowid/BlueLight Neuropharmacology Text List of FREE Chemistry Databases BEST Websites to Self-Educate Psycho-Pharmacology?? The Big & Bangin' Miscellaneous Chemistry/Pharmacology Odds N' Ends Thread: Part 3 (see also: v. 1 & v. 2)

bluelight.org

There is no excuse for elementary mistakes because someone has DONE all of the heavy lifting.

 

[MedicinalUser247]

Here's one for you. It's a new one. I have a drug design where Dizocilpine is spliced together with Fentanyl. The Dizocilpine is on the bottem and Fentanyl is on the top. its connected with the dibenzo at the top of Dizocilpines chemical ring which is attached to Fentanyls bottem amine.

 

[MedicinalUser247]

I also have another one. I took the main struture of THC and combinded it with DMT which the DMT is to the right and The THC is to the left making a single molecule. Half THC and have a Tryptamine. What do you think about all this ?

 

[MedicinalUser247]

I've got some more crazy ideas. Take the drug Herion and then add Methylecgonine to its CH3 chemical structure. So it has more euphoric effects. Whether it would be differently psychoactively i don't know. It may have some psychoactive effects of cocaine along with Heroin.

 

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OPTIMUS_PRIME
1-(4,4-dimethylcyclohex-1-yl)-1-oxo-2-(pyrrolidin-1-yl)-pentane

 

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CHARLOTTE'S_WEB
1-(4,4-dimethylcyclohex-1-yl)-1-methoxy-2-ethylaminopropane

We L.O.V.E You, Spider.

 

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Ask 4 HUSKER_DU.

 

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PAGE
1-(3,3-dimethyl-4,4-dimethyl-5,5-dimethylcyclohexyl)-2-aminopropane

 

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DOPE_REALIST
1-(3,3-dimethyl-4,4-dimethyl-cyclohexyl)-2-methylaminopropane

 

[Mjäll]

I also have another one. I took the main struture of THC and combinded it with DMT which the DMT is to the right and The THC is to the left making a single molecule. Half THC and have a Tryptamine. What do you think about all this ?

Shit man what if it rotates then

 

[MedicinalUser247]

Well.. I basically got rid of the 5 links to the right of the THC molecule and connected the tryptamine to that point. The only thing is that I have no idea how to put them together. I can only guess that those two molecules can be attached to each other to make a THC tryptamine molecule.

 

[tregar]

Recently, shed light said

I'm sorry if I missed it, but what's the dosing with this method? The wine from 15g/525 seeds is all consumed as one dose? Or is that split into multiple doses? Using this method, how much wine corresponds to a standard 100ug dose?

The 25g limit is the most I've ever taken...be prepared, still not vasoconstriction at 25g or below.

When you use the pure chemical isovaleraldehyde at a couple drops, then 100 seeds is indeed the equivalent of 100ug LSD, 200 seeds around 200ug of LSD. Unfortunately the average Joe will not be able to get this chemical any longer. You will need to substitute with a tablespoon of lemon juice, peppermint drops or peppermint tea instead, all sources of limited amounts of isovaleraldehyde.

Here is a post that goes way back in time to why peppermint tea, etc. works, no one understood at the time why it worked so well, now we know, 69ron suspected something else undiscovered in the peppermint was responsible, and he was right.

Special Note #1: 69ron (not me but a friend of mine from long ago, I have no idea what happened to him, but do miss him) once had a thread https://www.dmt-nexu...?g=posts&t=5733 on forming a potent Lysergamide psychedelic from LSA + peppermint tea. In this thread, you will find at least 5 bad ass reports scattered throughout the 11 pages. Just be careful if using HBWR seeds, as I have mentioned before, there are high amounts of ergometrine in HBWR seeds which cause cramping, vasoconstriction, and even bronchial vasoconstriction when ergometrine (not LSA) is adducted with acetaldehyde and other aldehydes as you will find some reports of this in the thread. If you use HBWR, just keep your dose low. Stick with morning glory seeds if possible, as they contain only trace amounts of ergometrine, see page 11 of the shroomery thread in the middle with pics on how to make the zero nausea MG liquid wine extract to use for your experiments. I prefer to use the pure ISOVALERALDEHYDE chemical found in peppermint whenever I can. At the time 69ron suspected some other unidentified aldehyde in peppermint besides acetaldehyde was responsible for the strong trips, he was right.

 

[MedicinalUser247]

Well... I got a computer and stopped using my phone to go on this website. The only problem I have now is trying to get Chemdraw. I tried downloading it from someone off this website, but it didn't work. They basically gave me it to download, but my computer wouldn't execept it. And the big problem is if you go to look for it online there all sold out.

 

[MedicinalUser247]

I think it would be intresting to see if someone could come up with Lysergic Acid 2,4 Dimethylaziridine. Hypothetically it could be stronger than LSD. I came up with this idea after looking at a few LSD analogs that are more potent than regular LSD.