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BDD Moderators: Keif’ Richards | negrogesic
Is lopermine water soluble
- Thread starter Ganjcat
- Start date
F.U.B.A.R.
Bluelight Crew
Lopermine? Do you mean loperamide?
Jabberwocky
Frumious Bandersnatch
don't tell me that you want to IV lope 
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Jekyl Anhydride
Bluelight Crew
No it's very slightly soluble in water.
Like:
So roughly 1.5 pills per gallon of water lol.
Like:
So roughly 1.5 pills per gallon of water lol.
kleinerkiffer
Bluelight Crew
Isn't there a loperamide lozenge/fast dissolving pill? That might decrease the time it takes to kick in
Jekyl Anhydride
Bluelight Crew
Considering the Bioavailability is 0.3% I doubt that trying to break it down before consumption would be of any benefit. Hacking ATC/ pGP is about the only way to "boost" it, but that gets dangerous and F's with the Dose-Response curve in unpredictable ways.
The generic brands break down in water very fast, like before you can swallow them fast if you swish a little.
The generic brands break down in water very fast, like before you can swallow them fast if you swish a little.
kleinerkiffer
Bluelight Crew
Edit (can't edit my post right now):
What I meant to say was given that it's more lipophilic than hydrophilic sublingual might work (but this shouldn't help much if your main goal is to decrease gut motility)
What I meant to say was given that it's more lipophilic than hydrophilic sublingual might work (but this shouldn't help much if your main goal is to decrease gut motility)
Jabberwocky
Frumious Bandersnatch
idk if this link would be allowed, but lope being otc and the site is for informational purposes only, you would like to buy something like this next time https://www.imodium.ca/products/imodium-quick-dissolve
Jekyl Anhydride
Bluelight Crew
While a mouth dissolving concentrated form looks more attractive I think it being brand name would make it cost prohibitive.
Jabberwocky
Frumious Bandersnatch
yeah it costs a little more but I'm sure other generics have this kind of form of lope too