• N&PD Moderators: Skorpio

How toxic is Mephedrone?

Fusion, I think the only thing you are really able to do is get your dosing under control and eventually quit altogether. The episodes you describe with sleep would certainly have me worried. I hope you manage to get your problem situated before anything serious happens, either by direct effect of the drug or indirectly, by the drug impacting your relationships with others.
 
am i the only one who thinks mephedrone got more toxic as it went along?

went i go it about 2 years ago the effects were there but for me it seemed to resemble real MD abit more and the negative effects werent' as pronounced

however, the shit i got just before the ban seems to alot more speedy than empathogenic and even though i take less it seems to fuck me over alot more; the vasoconstriction is alot worse

might just be my mind or can i get a c/s?

oh, and mephedrone seemed to give me permenant bruxism although it seems to have worn off now
 
Fusion, I think the only thing you are really able to do is get your dosing under control and eventually quit altogether. The episodes you describe with sleep would certainly have me worried. I hope you manage to get your problem situated before anything serious happens, either by direct effect of the drug or indirectly, by the drug impacting your relationships with others.

Hey, bol, thanks for the kind advice. I have been trying to take it easy and actually am down to two days on and two off.(which is good. For me.) I Got a 100 gram batch. So hopefully I can detox correctly. Crossing my fingers. ... damn stupid ego keeps knocking
On my door though....can't shut it offf. .. by the way..... go Celtics. Hope they stick t to Kobe that would be gr.eat
 
can you come up off mephedrone if you are on Mirtazapine?

I have a a buddy that takes mirtazapine, depakote, and adderall every day and he gets a full blown "roll" feeling on meph.

In my personal experience bingeing meph (I did 10g in a week more or less by myself) the main thing to watch out for is psychosis. After being up a few days on it I started to really hallucinate. Like that people were there i was conversing with not there, and I saw the light switch on the wall slide to the floor. All seems perfectly ok at the time 'cause i was so high. The culmination of the binge (maybe day 6?) i went out drinking with a buddy and ended up attacking him for apparently no reason, getting myself locked out of my apartment, lost my wallet. By this time i'm full blown paranoid seeing people in the trees, car bomb plots against me, crazy. the police were called bc i tried to kick my own door in at 4am, and i was in bad shape. Hallucinating everywhere and trying to tell the cops about the bomb in the truck by my apartment. It was way worse than any previous paranoia or anything I have experienced staying up multiple days using meth (I have not used meth now in 4 yrs). Luckily they called my mom and let her take me to her house where I promptly passed out.

Not to mention the extreme memory problems that seem apparent almost from the beginning, lots of everyone asking "what was I just saying?" or just dropping off in the middle of the sentence. Also, it really fucks with your motor control, and makes tasks like typing nearly impossible. I sent so many fucked illegible nonsensical txts and e-mails that week it was ridiculous. Plus, mixing with alcohol results in blackouts for me (mdma does this as well).

Do I think it's "safe" no. Will I use it again? more than likely. Will I use it for a whole week ever again? I sincerely hope not. That was just stupid. I will say that all hallucination and paranoia was resolved with sleep. After a couple days my memory and motor skills began to feel normal again. Personally, based on my experience of it's profound effects on memory and motor control I am more than willing to bet on this being neurotoxic as well as the well documented vasoconstriction. It does feel amazing though. Also the high from eating it is much different from snorting it. I think i prefer to eat it, but I was snorting it a lot, too. I think i was too high the whole time to be bothered with noticing things like fast heart beats, coldness or numbness in the extremities, etc. It was all just great until I started freaking out from no sleep, plus I really feel that meph itself can give mild visuals on it's own.

Cheers,
-SimStim
 
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Withdrawing - zaps, discontinuation syndrome

The worst thing for me when I was so addicted was the fear of the withdrawal 'zaps' aka discontinuation syndrome.

Surprisingly, high doses (up to 5g per day) of l-tyrosine - available from health food shops like Holland and Barrett - completely stopped them, which makes mr
wonder whether the zaps are due to dopamine/norepinephrine imbalance and not serotonin?

If you can't source l-tyrosine, dl-phenylalanine is also effective.

I switched to l-tyrosine and tapered my dose over a month rather than trying to taper off meph as it's so hard to not redose compulsively. Both tyrosine and phenylalanine are reported to have applications in managing some forms of drug addiction, although I don't recall reading about it in the context of mephedrone previously.

When I managed to stop in March - just before the ban - my regular supplier was sending out the most impure stuff I've ever taken; chest pains within an hour of taking it, the batch smelt strongly, and the colour was very yellow. I'm glad I stopped when I did - my BP was through the roof, especially in my pulmonary artery.

Since then everything is, touch wood, returning to
normal - BP, chest and cardiac sounds, only one tachy-arrhythmic episode which subsided within a few seconds - and i'd say I'm almost back to being a normally-functioning person without feeling the urge to get high every couple of hours.

Good luck tapering off.
 
ur of taking it, the batch smelt strongly, and the colour was very yellow. I'm glad I stopped when I did - my BP was through the roof, especially in my pulmonary artery.

how the fuck do you know what your BP is in your pulmonary artery whilst taking mephedrone 8)
 
Oh Vecktor, come one! This shouldn't be too difficult to do at home:



This could be easily improvised with some copper wire, an old vacuum cleaner and some tiny screws. I frequently check my BP in all kind of vessels with a modified pipe wrench. That saves a lot of costs! Yes yes...

- Murphy
 
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I have never seen nor done Mephedrone. To my knowledge it is unavailable in the United States (in head shops at least) even though it is unscheduled ( at least I think it is)

My question is: in the long run would weekend binges of coke or meph be more damaging to the heart.

Also, why did no head shops in the US catch on?
 
how the fuck do you know what your BP is in your pulmonary artery whilst taking mephedrone 8)

Oh feck, now I feel rather silly... :-$

Ok, truth is I may have made an uneducated guess based on what I could feel and many hours of research but, no, you're right - I'm a tool for making that assertion.

What I **should** have said was: I could feel - especially when lying down - my pulse throbbing very hard up the left side of my neck. There was considerable discomfort caused by a sensation of pressure which worsened significantly when I lowered my head so my chin would touch my chest. I frequently had tingling/pain in my jaw, usually at the left-back. I experienced chronic and acute discomfort of varying intensity in my left chest area, usually below the breast bone or below the bottom rib.

It was impossible to lie on my left side, and even the weight of my left arm on my chest would cause sudden chest pains.

I was also getting seriously out of breath when I was sitting still - for example watching tv on the sofa before bed - and lying down would normally make it worse. Walking around the house would sometimes help to clear it a little; otherwise I just had to wait it out. I often ended up falling asleep half-upright on the sofa at 4 in the morning because I'd woken up in pain.

I'm an otherwise fit and healthy male, late 20s, average height, average/slightly muscular/slightly overweight build. I.e. nothing out of the ordinary and certainly nothing which would explain these signs and symptoms.

And yes, it scared the cock out of me :o(

Since stopping the pains have gone, the sensations of pressure have gone, the discomfort has gone. I'm not "right" still, and I often find myself craving intoxication, but I don't constantly worry that I'm going to end up karking it suddenly, and things like running for the train don't leave me with my heart hammering away in my chest, out of breath, and sweating like anyone's business.
 
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would mephedrone's 5-HT/DA/NE release be potentiaed or mitigated by an SDNRI like tramadol? Instinct says potentiate, but I didn't believe the SSRI MDMA blunting until it happened so me, so these things aren't always intuitive.
 
I have never seen nor done Mephedrone. To my knowledge it is unavailable in the United States (in head shops at least) even though it is unscheduled ( at least I think it is)

My question is: in the long run would weekend binges of coke or meph be more damaging to the heart.

Also, why did no head shops in the US catch on?
US has analog laws which make it's legality sort of a gray area. Possesion of small quantities ordered from overseas is unlikely (but not impossible) to result in prosecution. But selling it a different story. People have been busted for selling RC's on the net (google web tryp) in a headshop it would get you arrested in short order. But there are plenty of vendors who will ship it here. Ordering RC's isn't that dangerous, I've never even gotten a love letter.
 
Yeah, its pretty clearly, according to the Controlled Substance Analogue act, an analogue of methcathinone, which is specifically controlled. Basically I think it's lack of popularity has kept it off the radar
 
Count me in as another casualty. I did a few grams over the weekend and my forearms are blue, yellow, purple. a scary rainbow. It's been 5 days, and I've been trying to follow advice.
Warm baths for my arms. Light exercise, massage of the area, Viagra a few times a day, avalide twice a day. Lots of water, no alcohol. Truth is, I'm scared, nothing is changing, not better, not worse, but what about gangrene, will I feel that coming on? will it become darker, even black? Please help if you don't mind. I apologize for being redundant. But as I hate to admit,I really am scared. I have a BAD relationship with the doctors here, so that's my last resort. Thanks
 
what about gangrene, will I feel that coming on?
I'm pretty sure that gangrene is both visually obvious and excruciatingly painful, I don't think you can have gangrene and not know about it.
 
I can only say that I ate over 20g in six months.

I heard somewhere that 3 tons were consumed in the United Kingdom in less than 2 years.

And I don't think there were many if any deaths directly attribtable to this.
 
without having to read the whole 34 pages of this thread, are blackouts very common when mixing with alcohol? this happened over the weekend (i lost 4 hours or so)
 
without having to read the whole 34 pages of this thread, are blackouts very common when mixing with alcohol? this happened over the weekend (i lost 4 hours or so)

In my personal experience mixing alcohol with significant doses of either mdma or mephdrone will eventually result in blackout, not to say you might not still be up and running around. Not a beer or two mind, but you will feel like you can drink a lot and maybe not quite so much as it seems, and then you don't know how much you drank.
 
In my personal experience mixing alcohol with significant doses of either mdma or mephdrone will eventually result in blackout, not to say you might not still be up and running around. Not a beer or two mind, but you will feel like you can drink a lot and maybe not quite so much as it seems, and then you don't know how much you drank.

I drank around 15 cans of stella with a gram of meph. usually 8 cans will fuck me up. i didnt even have a hangover, was a strange one.
 
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