Short answer, no. Depends how long you have been using 250ml and at what rate. Still I would argue, that you would be pretty much safe...the Ibuprofen affects the kidneys more my man. Next time use less water...2-3ml per tablet.
I used to CWE wrong for a while....I used to squeeze 72 Ibuprofen + Codeine tablets in a tshirt, letting a SHITLOAD of Ibuprofen through. I have since been to multiple check ups after switching to APAP and pure opiates. Claimed I was a hardcore drinker and wanted Kidneys checked each time. Kidneys were fine. So was the liver.