Once a week for me. Ive only been on the shit for about 4 months and im going hard with no less and no more than once a week. My tolerance is building im having to take 2-4 each night now. The reason im still going this hard is because im still feeling 100 percent, ive only had one bad come down(found out later the pill had acid in it), and im just having to much fun with mates at the moment. As soon as my tolerance is too high to afford to take it and my comedowns outwiegh the come up and peak i will be giving it a rest for a bit. untill then im gonna eat them up like crazy.