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Bupe How does suboxone get along with others?

E

Explodey1

Greenlighter
Joined
Oct 7, 2020
Messages
3
When I first got on suboxone, I was transitioning off of methadone maintenance, and the transition was difficult. And the doctor said something that I always remember -- she said, "When you kicked oxycontin, it's too bad you didn't immediately get on suboxone, because it's a really easy transition from oxycodone to buprenorphine. But methadone and bupe just don't play well together." So I had to get pretty sick before I could start getting the benefits of the bupe.

Anyway, my point is -- I'm curious what other drugs do and don't go well with bupe. Does anyone have experience with this? Has anyone tried taking a "buprenorphine holiday" so they could get high? How long did you have to wait? How'd it go?
 
the longer the half life the worse the opioid is to switch to bupe from. That’s one reason methadone is the worst it has such a long half life. Fentanyl is one of the easiest to switch from.
 
I find that I can transition from tramadol to bupe & vice versa no problem.
In fact, taking tramadol on top of low doses of bupe is pretty nice.

I also have never noticed much switching from hydrocodone back to bupe either.


It was usually heroin that I'd get precipitated withdrawals from.

And although fentanyl is a short acting agonist, it does hang around in fats & what not in the body, meaning you might have PWD when switching from fentanyl to bupe.

I personally think the more potent an opioid is, the harder it'll be to transition to bupe from, rather than half-life. Although the half-life does matter to some degree too. But for example, tramadol has a longer half life than hydrocodone, but I can switch from trams to bupe just fine, because bupe is incredibly way more potent. But the effects of bupe are more boring in comparison to tramadol or tramadol/bupe combo.
 
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