Opioids heroin after methadone?

[jholdaw2]

Ok so I was on methadone for a year and noticed these so called "blocking effects" of methadone. When I took 80mg oxycontin, absolutely nothing would happen, when I would take a relatively large IV dose of heroin, I would feel a rush, but afterwards there was no lingering high whatsoever. I am sure this is because of the methadone...I stopped taking the 80mg methadone I had been on for a year cold turkey, and it still took ~4 days before I could start to feel other opiates again.

Now my question is, I had been off methadone for 2 months (though using other opiates during this time) but have restarted, taking 50mg for the past 4 days...I have some heroin im planning on IVing, but I don't want to waste it...Do methadone's blocking effects present themselves after a single dose of methadone, or do you have to be on daily methadone for a while before the blocking effects become noticeable? how long do you have to be on daily methadone? How long should I wait after my last methadone dose before getting favorable results from my heroin dose?

Thanks to anyone who can answer this!

 

[thelung]

You should wait until the methadone is out of your system before IVing the heroin you have. How long does it take for the methdone to get out of there? hard to say exactly, probably at least 4 days.

 

[HdoubleODeezy]

^ i agree.. 3-4 days.

edit: just realized you said at least 4 days.. well at least i agree on the 4 days part lol.. but as little as 3 is possible. depends on your metabolism. also depends on heroin dose.

 

[thelung]

^right, everybody is different in how slow/fast they metabolize medications

 

[Princess_Poppy]

yeah, i'm on 50 (although everyday) and it defiantly does a good job of blocking. ditto.

 

[splenda]

Methadone's blocking effects start as soon as you get on them, but at 50mg you might be able to get a 'slight' effect from a high dose of H although if I were you I wouldn't risk it (as it could easily lead to OD.) The more the methadone has built up in your blood stream (i.e. the longer you've taken the methadone), the more the 50mg will 'block' other opioids.

I'm on 150mg and I notice complete blockage... it'd be a complete waste of time for me to do any opioids. If anything, if I was REALLY desperate for a 'buzz', I'd take a couple cimetidine (CYP450 inhibitor that inhibits methadone metabolism, thereby increasing methadone plasma levels) before my dose.

The thing is though, on methadone you shouldn't have any cravings to use other opioids or to double-dose your dose, etc. If you get cravings it means you should raise your dose higher. My cravings to use/to double-dose/etc. didn't go away until I reached 130-140mg of methadone. Good luck!

BTW, you're in Hawaii too? Nice. Which clinic do you go to, DASH or CHAMP?

 

[myfriendemo]

wow, you have heroin and you haven't IV'd it yet? i'm impressed.

 

[leigh12]

if i smoked and snorted 200mg quickly wld it hit me? it on 120mg methadone , last meth dose was 70mg at 5 am this mornin