Done safely I think GHB or GBL are one of the safest drugs. I'd say taking G properly, and in its pure form, and not redosing too soon, and knowing your G limits is safer than taking a pill you have read is good on PillReports.com. And if anyone disagrees I'd like to see some good discussion on it. Not just the normal anti-G BS.
But with 1,4b I'd lean towards signs of organ damage, especially when abused. G is addictive, GBL is more addictive than the others but provides the quickest, strongest rushes and come-up. GBL can cause more stomach upsets, so dilute it properly, with 1,4B you can dose in a syringe and just squirt it into a mouth full of water/softdrink/fruit juice and swallow then have a chaser. 1,4B tastes sweet to me, but in a weird plastic, fake way. More like Cough syrup than bitter.
1,4B has a dual action of being a potent alcohol solvent and converts to GHB using the same liver enzymes.
To know if its pure put it in a fridge for about 15-20 minutes and It should look all frozen, crystally and cool! Leave it in there for longer and it should remain totally solid. If there's excess liquid going around it then it's been watered down.
To be honest if 1,4B was the only thing available to me during my G addiction. I wouldnt care about it. Personally i think its not very good and GBL is where its at, good luck trying to find that.