Energizing/embodiment strain

[Allylbenzene]

In Britain we have online vendors with CBG isolate and high CBG hemp strains/extracts. From a quick search I see you have vendors selling lab tested 20% CBG strains.

 

[Allylbenzene]

I don't really know what CBG stands for specifically, but when it's present over 2.5% in my product then I'm pretty much gonna grab it regardless of the other numbers. CBG been doin' me RIGHT and it's a damn shame I don't know exactly what it is.

CBG is the plants precursor for THC and CBD. It's pretty unique because it's main effect is to block adrenaline and increase natural opioids. It does this by activating a receptor called "alpha-2 adrenergic". It only slightly activates the cannabinoid-1 receptor iirc.

 

[Jibult]

CBG is the plants precursor for THC and CBD. It's pretty unique because it's main effect is to block adrenaline and increase natural opioids. It does this by activating a receptor called "alpha-2 adrenergic". It only slightly activates the cannabinoid-1 receptor iirc.

It blocks adrenaline?!

That's it. That's how it calms me down.

I'm often barraged with fight-or-flight responses to things that just don't warrant it. I've never been diagnosed but a few doctors have noticed that I seem to have adrenaline dumps in their offices. It normally comes to light when they're trying to get a read on my blood pressure.

 

[Allylbenzene]

It blocks adrenaline?!

That's it. That's how it calms me down.

I'm often barraged with fight-or-flight responses to things that just don't warrant it. I've never been diagnosed but a few doctors have noticed that I seem to have adrenaline dumps in their offices. It normally comes to light when they're trying to get a read on my blood pressure.

Ah, look into an "overactive stress response". Theres some dietary factors that can contribute to this (eg phytoestrogens, polyunsaturated fats).

The stress-related hormones (cortisol & estrogen) work partly via adrenaline which is excitatory (stimulating).
The body has it's own anti-excitatory calming things like agmatine, progesterone, GABA & endocannabinoids. These calming things balance out the effects of adrenaline, cortisol, estrogen, glutamate and histamine (think how anti-histamine drugs can be sedating).

Terpene wise the best anti-adrenaline ones are linalool, myrcene, bisabolol/bisabolene, caryophyllene, humulene and nerolidol.
Also limonene but it can have an energising/uplifting/euphoric effect...

If you're open to supplements there's an extract from green tea called theanine that stops the stress response.
There's another one called agmatine which is directly anti-adrenaline and anti-glutamate.

You can also encourage your body to make more progesterone by supporting your metabolism.

 

[scabbard]

I bought a high CBG strain, this stuff:

CBG White Hemp Flower

Aroma: Light and earthy with hints of lemon. This genetic marvel was built on the CBG Stem Cell foundation. CBG White's development includes a better resin content and a higher terpene profile. Bud Structure: The fairest of all with a super light green color and covered in white frosty...

horncreekhemp.com

By the way, props to this company, I spoke with a guy there named Paul and he was extremely helpful in answering all of my questions, fast shipping, they even threw in some CBD gummies to try. I was very pleased with our interaction.

Anyway, this stuff has 20% CBGa by weight. When burned (or smoked), the CBGa gets converted to CBG which is what produces the effects. Most of the guides I've found online for dosing recommendations specify the amount of pure CBG to take. Does anyone know the chemical reaction when you burn CBGa, and how much CBG you'll end up as a result of the combustion?

 

[Allylbenzene]

It's probably similar to the rate for THCa to THC (which has probably been worked out somewhere).
btw for joints much of it will be vapourised and not actually burnt. For bongs if you leave a small gap between the flame and the flower you can vapourise it which is way more efficient.

 

[scabbard]

Why would much of it be vaporized for joints? I would think direct contact with a flame would burn it.

 

[Allylbenzene]

Yes, maybe when you are relighting the joint; but otherwise the "ember" mostly vapourises material before burning it.

 

[emkee_reinvented]

Sure. Now that you have an idea what effects those terpenes have, it could help to choose suitable strains.



What I wrote about stimulating & relaxing terpenes was literal. Well...many terpenes have both stimulating & relaxing qualities but I was writing about the dominant effect.

Terpinolene strains would be a good fit for your needs. Along with citral it's the only terpene I know that interacts with 5-HT2A which is the receptor associated with psychedelics (LSD, magic mushrooms, DMT etc).

You could try terpene isolates sure, it's a good way to see what they're like. You could also use essential oils ("pre-mixed terpenes") that are described as having the effect you're after. In the sense that people know the effects of a strain, people know the effects of essential oils.

It sounds like you're looking for uplifting, mental calm + focus with subtle body relaxation effects. I'd go for a mix of lemon (uplifting, focus), lavander (calm, body relaxation), sandalwood ("zen"), optional: lemon myrtle (introspective)

Lemon oil for the limonene & smaller % of pinene. Lavander oil for the linalool. Sandalwood oil is a unique one you won't find any dispensary strains for. Lemon myrtle oil is mostly citral.

Diluted in some coconut/olive oil and applied to inner wrists/arms I found works well.

Keeping it simple, the best oil for somatic release is Sandalwood so combined with cannabis = excellent.

Cat s get high,by just smelling Catnip, a 15 minute Opioid/ Hallucinating high.
Conforming it impossible as my cat does understand me better the i did her.

Wonder which Terpene, best guess, in catnip is responsible.
https://en.wikipedia.org/wiki/Nepetalactone , no Terpene a Nepalactone

Lavender oil, does have direct effect on human rest, through the nose.

https://flowerpursuits.com/why-does-lavender-relax-you/#google_vignette

 

[Skorpio]

Cat s get high,by just smelling Catnip, a 15 minute Opioid/ Hallucinating high.
Conforming it impossible as my cat does understand me better the i did her.

Wonder which Terpene, best guess, in catnip is responsible.
https://en.wikipedia.org/wiki/Nepetalactone , no Terpene a Nepalactone

Lavender oil, does have direct effect on human rest, through the nose.

https://flowerpursuits.com/why-does-lavender-relax-you/#google_vignette

Cats, unlike humans have working vomeronasal organs (which respond to pheromones). Ours have lost their neural connections and are vestigial, so humans are unlikely to have as powerful of a response to a smell.

I did talk about this, all 3 charts are technically right.


Overall linalool is sedating & mentally relaxing via it's actions at GABA + adenosine (which are both inhibitory aka calming) and reducing the effects of glutamate.
The pinenes (theres 2 different versions) have a combination of uplifting/stimulating effects (via D1 + 5-HT1A receptors, increased dopamine, increased acetylcholine, BDNF) and calming effects (via GABA, opioid).


I don't recommend trying this in such high doses but here's an example of what theraputic-grade lemon oil can do.
Lemon oil contains ~60% limonene, ~20% beta-pinene.

Nature's Herb Forum-Lemon Oil is Definitely Psychedelic!

So far I've done 3 high dose experiments with lemon essential oil, and I've experienced psychedelic effects all 3 times. 1st experiment (30 drops lemo

www.tapatalk.com

So it's all about the dose really. 5 drops of lemon oil might be calm + uplfting but 20+ drops things get more energising and euphoric.
In a sense, THC will tend to amplify the terpene effects in it's own unique way.

Also if something reduces cortisol (stress) then that will have an uplifting effect and greatly facilitate any healing practices.
Since you're looking to support somatic release and nervous system work, I'd prioritise anti-stress, good mood (uplifting), focus and calm. From experience i'd say Sandalwood does this quite well, but terpene wise - lemon (limonene, pinene), lavander (linalool) + cannabinoids works too. Or both cannabis + Sandalwood for synergy.

That alpha-pinene paper uses doses of 20-100 mg/kg to see effects in mice. That has almost no relationship to the concentrations which humans are exposed to in cannabis or aromatherapy. Even scaling for metabolism, that still works out to basically drinking a shot of pure terpene to get the effects they got.

 

[Allylbenzene]

That alpha-pinene paper uses doses of 20-100 mg/kg to see effects in mice. That has almost no relationship to the concentrations which humans are exposed to in cannabis or aromatherapy.

Regardless, from an actual practical perspective 1 drop pure alpha-pinene is sufficient. It works well stand-alone but is best combined with others like ocimene, phellandrene, valencene and limonene. Dermal absorption is far more efficient than ingestion but possibly comparable to vaping/smoking.

That alpha-pinene paper uses doses of 20-100 mg/kg to see effects in mice.

I think relying on those kinds of studies for navigating dosages and deducing potency will always blind the reader to anything practical.