I’ve never had to kick, but pregabalin is always raved about in the acute phase.
It’s been discussed plenty of times buts it’s the post phase that’s the issue.
I’m not 100% sure what the fastest way is, but forcing the brain to adapt to endogenous production is key.
I think going as cold as possible is better with comfort meds to force those adaptions.
The Endocannabanoid system is largest in the body and has downstream effects on opioid and dopamine.
In the PAWS, I’d say TL4? (Or TLR4 can’t remember which is the acronym) is linked with issues that cause cravings and relapse but plenty of agents that can alleviate TL4 malfunction like Agmatine.
Proper usage of Cannabinoids can modulate the endocannabanoid system (CBG, CBD, THC) and therefore I speculate will help adapt the system as a whole.
Low dose THC can up regulate receptors meaning it can strengthen endogenous function and lower tolerance to THC if done right. (I’ve smoked 0.25g of THC weed a day for a year and half and never need to increase the dose and always get high)
CBG has tolerance and TL4 mechanism (CBG is also a shit hot A2 Agonist, means you can mega dose THC, a big bonus for AWS when you feel like shit, as THC can worsen it if used on its own)
CBD makes THC more medical, smoothes out side effects and still contributes importantly.
Agmatine will increase the effectiveness of Cannabinoids, reverse TL4, lower tolerance and therefore dependence, Is a A2 agonist, relieving AWS, but due to NMDA activity, will lessen PAWS, due to intense antidepressant activity.
Exercise especially heavy hypertrophy training or high intensity cardio can cause insane adaptions and I think this has been proven to restore a brain to pre drug states.
I lift weights everyday, but also do my proper sessions at the gym 2x a week which are brutal fullbody sessions.
(As if I had no tolerance) The home sessions feel like a 60mg codeine, those brutal fullbodies is like 120mg codeine.
Every-time it works and I suspect it ensures my endogenous production of endorphins works as it should.
I have never been dependent on heroin, and never on opioids physically so I can’t speak for sure.
I’m just a guy that blasts few a few grams of codeine or DHC every so often.
When I wasn’t taking the Agmatine, things got really bad and I never struggled with cravings so bad. Never got sick but I’m sure I was in touching distance.
That time I was using 420mg of DHC 3-4 times a week.
The last time with lots of TL4 agents, I stopped far easier, and with 2weeks of Black seed on top, I was craving free, and was getting fuzzy from Paramol and a few more weeks, my tolerance is so low I’m puking from only 210mg codeine.
After a few weeks without again, a 50mg tramadol was enough to work decently and enjoy it.
I’m not saying I have the answers, but I know what it’s like to have a brain that craves opioids as a medicine. I have reliably rewired it to not see them so or crave them SO bad.
I’m still a fucker, I will crave them (not like a proper craving, just oh I fancy it) and still use them because Opioids piss all over other drugs.
They are awesome and physically benign apart form not shitting!
But I have my own opinion, that you can use them but have to accept they have stipulations and can only be used temporarily with other things to ensure your brain isn’t manipulated.