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EADD Heroin thread v.XXV -- a quarter centuary of threads if not yet a full decade since the 'drought'...

This guy is brilliant But at the same, time I despair for our world...



And before anyone screams 'rascist', the white imbeciles are just as bad as the black ones.

I just love the face on the interviewer when he receives a wrong answer :ROFLMAO:
 
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Methadone is a Pure Horror Show.
I've made the biggest mistake getting a habit on this stuff, it's actually worse on my body than Heroin & when you begin to get Methadone Sick oh God above do I feel it.

The Methadone sickness seems to start in my guts first when Heroin begins in my legs, the sneezing off Meth is worse too, I sneezed 13 times in a row earlier today so hard it hurt my throat.
 
Methadone frequently causes severe, chronic constipation (Opioid-Induced Constipation, OIC) by slowing gut motility, often requiring proactive management because tolerance to this side effect rarely develops. Unlike other side effects, constipation does not typically go away as your body gets used to the medication. If you experience severe abdominal pain, nausea, vomiting, or stop passing gas/stools, you should contact a doctor, as severe constipation can lead to serious complications.

I swear to God the last 2-3 days it's 100% SURE in my Mind people need a LEGAL Heroin Script, Meth is Poison & that Espranor made me rattle like I've never known, I turned GREY in the face ffs coming off that stuff in less that 4 hours!!!!!.
 
Without question on that one.
Heroin has a grip on me worse than MDPV ever did.

I think I will be on some form of Opiate till I die sadly.

Honestly mate, if you think like that, you will be.

You need to change your mindset, but it's easy for me to say as I don't know your circumstances.

All I know is that I once thought like that, until I realised I had too much to lose.

It's fuckin hard, but you don't have to be a lifer.
 
Without question on that one.
Heroin has a grip on me worse than MDPV ever did.

I think I will be on some form of Opiate till I die sadly.
Well, it's not the end of the world now is it?

If you can figure out a way to manage it and live some sort of fulfilling life beyond drugs is it that big a deal?

Like @F.U.B.A.R. says, change your mindset or accept the situation and figure out the best way to manage it so you can live a fulfilling and happy life. But don't let drugs be your life.
 
I’m 63 and been on opiates since 19 with a few gaps. Back on a script now 60 mg forgot to take my dose yesterday but due to the ridiculous half life of methadone it made no difference except I now have a spare. I will chip prolly once or twice a week till I die… no problem with that I need to take a bp tablet daily so what’s the difference. Oh I don’t have the intestinal issues Zopi has.
 
I just met 'Tilly', who's a proper begging street junkie, but says she sticks to her script. But she missed her dose today because the pharmacy closes at 1pm, which it always has done.

I thought she was following me home, but she went back to her place. Said she'll be alright with pregabalin, but I bet she scores.
 
Aye? Do you think full time pregabalin would kill the opiate urge eventually? It's not my experience of it anyway. Although it's a decent wee gabapentinoid.
Killing the urge is about mindset more than taking a drug. If you want to get off it then it's time to strap in for a very uncomfortable ride.

I could diminish it and say sack up and power through it, it's not like alcohol withdrawal which you can actually die from.

But yes, I do believe it will make the urge less so. But your milage may very well vary.
 
I’ve never had to kick, but pregabalin is always raved about in the acute phase.

It’s been discussed plenty of times buts it’s the post phase that’s the issue.

I’m not 100% sure what the fastest way is, but forcing the brain to adapt to endogenous production is key.

I think going as cold as possible is better with comfort meds to force those adaptions.

The Endocannabanoid system is largest in the body and has downstream effects on opioid and dopamine.

In the PAWS, I’d say TL4? (Or TLR4 can’t remember which is the acronym) is linked with issues that cause cravings and relapse but plenty of agents that can alleviate TL4 malfunction like Agmatine.

Proper usage of Cannabinoids can modulate the endocannabanoid system (CBG, CBD, THC) and therefore I speculate will help adapt the system as a whole.

Low dose THC can up regulate receptors meaning it can strengthen endogenous function and lower tolerance to THC if done right. (I’ve smoked 0.25g of THC weed a day for a year and half and never need to increase the dose and always get high)

CBG has tolerance and TL4 mechanism (CBG is also a shit hot A2 Agonist, means you can mega dose THC, a big bonus for AWS when you feel like shit, as THC can worsen it if used on its own)

CBD makes THC more medical, smoothes out side effects and still contributes importantly.

Agmatine will increase the effectiveness of Cannabinoids, reverse TL4, lower tolerance and therefore dependence, Is a A2 agonist, relieving AWS, but due to NMDA activity, will lessen PAWS, due to intense antidepressant activity.

Exercise especially heavy hypertrophy training or high intensity cardio can cause insane adaptions and I think this has been proven to restore a brain to pre drug states.

I lift weights everyday, but also do my proper sessions at the gym 2x a week which are brutal fullbody sessions.

(As if I had no tolerance) The home sessions feel like a 60mg codeine, those brutal fullbodies is like 120mg codeine.

Every-time it works and I suspect it ensures my endogenous production of endorphins works as it should.

I have never been dependent on heroin, and never on opioids physically so I can’t speak for sure.

I’m just a guy that blasts few a few grams of codeine or DHC every so often.

When I wasn’t taking the Agmatine, things got really bad and I never struggled with cravings so bad. Never got sick but I’m sure I was in touching distance.

That time I was using 420mg of DHC 3-4 times a week.

The last time with lots of TL4 agents, I stopped far easier, and with 2weeks of Black seed on top, I was craving free, and was getting fuzzy from Paramol and a few more weeks, my tolerance is so low I’m puking from only 210mg codeine.

After a few weeks without again, a 50mg tramadol was enough to work decently and enjoy it.

I’m not saying I have the answers, but I know what it’s like to have a brain that craves opioids as a medicine. I have reliably rewired it to not see them so or crave them SO bad.

I’m still a fucker, I will crave them (not like a proper craving, just oh I fancy it) and still use them because Opioids piss all over other drugs.

They are awesome and physically benign apart form not shitting!

But I have my own opinion, that you can use them but have to accept they have stipulations and can only be used temporarily with other things to ensure your brain isn’t manipulated.
 
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