Dexamphetamine is a straight street drug

[HiLiKuS]

Yeah I figured as much however just entertaining a thought. It might also be best that these therapy sessions are conducted in a dark room save for a few lasers and loud music.

 

[drug_mentor]

Puckboy I am pretty sure crankinit is right in saying most European 'speed' is racemic amphetamine. There probably is pure dextro amphetamine about but I am fairly certain the common synthesis routes end up with racemic end product.

Pharmaceuticals are definately under rated, and that includes pharmaceutical stimulants. That said, when it comes to stimulants none of the pharms can really substitute smoking high purity stimulants IMHO. As hyroller already pointed out though, there is quite a difference in the cost between the two.

 

[Azron]

well you get what you pay for...

 

[localized]

Yeah I figured as much however just entertaining a thought. It might also be best that these therapy sessions are conducted in a dark room save for a few lasers and loud music.

lol. that would get most Aussies jumping up and down to join the army

 

[omegapoint]

Can someone who knows about Dexamphet, 5ht, cardio, etc. Please PM. Thanks.

 

[Mr Blonde]

^ You can't respond to PM's as you are a greenlighter. Why don't you just post your question in this thread?

 

[omegapoint]

Anyone know interaction of acetyl-saliylic on urinary ph AND efects of using aspirin for cardio purposes whilst in d-amp (chronic/"get high") state...

querying Cyclooxygenase, Thromboxane, and other specific enzymatic reactions with d-amp and other substances...

also want to know what minerals (Ca, Mg, etc) best to recover gycologenesis...

At point where have pretty tight left side - under armpit twitching, sore left eye (close at bright light but ok otherwise/little twitchy)... etc...

Yes - I should STOP but having to do so SLOWLY...

Started with 100mg dAMP. Now on about 50mg-100mg a day. No psych symptoms but NO SLEEP.

Major issues:

Cardio hard pumping but only 96 normal HR for me...

MOST MAJOR ISSUE:

Got into opiate-like-WITHDRAWL (sweats, twitches, unable to keep still) from attempting to sleep with NO d-AMP... ie: after 6/8 hrs of NOTHING I go into Withdrawl (physiologically apparent to me)...

Considering attempting sleep on small dose as have read in places the paradoxical consumption of more d-AMP may keep body in homestatus-quo (loaded) and enable possible sleep if but for mind (which CAN prob control)...

main q is what can I do to stop cardio/twitches OTHER THAN STOP d-amp ?

3 weeks now been UP.

 

[Mr Blonde]

^ Aspirin will only help if you take it daily. You can get 'Cardix' or whatever it is called from the pharmacy, ask for a generic... you will get 100mg tablets in a 112 tablet box for about $3-4.

I haven't seen the 82mg ones in pharmacies in the Brisbane CBD, but they would be around and perfect for that use.

You know about COX and thromboxanes, and that's all good... but aspirin is not going to help a lot with cardiovascular issues brought about from chronic dexamphetamine use.

The blood pressure problems and the heart issues are brought about by the vasoconstriction the drug causes. The thromboxanes act as stimulants of platelet creation and platelet aggregation. By inhibiting these lipids, you will bring down your risk of clotting somewhat.

But it can take a little while for aspirin to start having this effect, and at the same time you are continuing to push your cardiovascular system too hard. That vasoconstriction is still going to be there which will put you at a larger risk for a clot related event, and it already sounds as though you are doing yourself serious harm or on the verge of it.

also want to know what minerals (Ca, Mg, etc) best to recover gycologenesis...

Do you mean glycogenesis or gluconeogenesis? The former is the synthesis of glycogen from glucose, and the latter is the production of glucose from non-carb sources. Or do you just want your body to produce more energy from your food? If that's what you want, I'd recommend some low GI foods so that you don't burn through it all too quickly.

Are you eating healthy already?

Also, magnesium can help with muscle tension. Magnesium supplements are good for this purpose, I've seen BL'ers recommend them for MDMA 'gurning' before.

 

[lagger]

I went through 12 bottles in about 2-3 weeks once.
I managed to rack myself up huge credit debts i cannot pay off due to buying shit online!
Very obsessive shit. I also lost about 20KG lol. and in the second week the only trhing that would put me to sleep were about 20+ dexxies.

DO NOT TRY THOSE DOSES WITHOUT TOLERANCE.. or at all really....

 

[TangerinO]

Interesting topic of discussion. I actually have ADHD and a mild case of Autism. I actually find that the methylphenidates work much more effectively for me, and have definitely had a positive effect on my life as a whole. As for Dex abuse, I admit to taking large doses of it to get amped up at parties or also just a cheap way to stay up at a concert or whatever. That being said I don't really do this anymore as I find it just tweaks me out so hard it makes the experience more inclined to be unenjoyable.

 

[Mr. Squiggle!]

*sighs*

 

[omegapoint]

I went through 12 bottles in about 2-3 weeks once.
I managed to rack myself up huge credit debts i cannot pay off due to buying shit online!
Very obsessive shit. I also lost about 20KG lol. and in the second week the only trhing that would put me to sleep were about 20+ dexxies.

DO NOT TRY THOSE DOSES WITHOUT TOLERANCE.. or at all really....

No weight loss... Am eating... probably low/normal DIET... but I FEEL IT IS NOT ENOUGH FOR ME: burning too much... Hyperthermic too...

Wondering with gluco/glyco (Mr.Blonde) about BOTH +affects of D-AMP on ATP=???

So what is recommended to stop???

Started 3 weeks ago. Heart RATE seems ok. Possibly BP Hypertens but here is the deal:

WHEN ONLY I ***STOP*** do I GET HYPER!

ie: Does d-amp metabolise to p-Hydroxynorephedrine? or p-Hydroxynoramp???

if so then FAKE NEUROTRANSMITTER in that PHN uptaked as NE substitute:

doesnt have same affinity perhaps ???

Adrenergic terminals agonized thus HIGHER than normal response by NORMAL NE levels returnin as I COME DOWN ???

Just wondering if this is possible: PARADOXICAL EFFECTS.

Took 24 Dex last night and SLEPT.

 

[omegapoint]

^ Aspirin will only help if you take it daily. You can get 'Cardix' or whatever it is called from the pharmacy, ask for a generic... you will get 100mg tablets in a 112 tablet box for about $3-4.

I haven't seen the 82mg ones in pharmacies in the Brisbane CBD, but they would be around and perfect for that use.

You know about COX and thromboxanes, and that's all good... but aspirin is not going to help a lot with cardiovascular issues brought about from chronic dexamphetamine use.

The blood pressure problems and the heart issues are brought about by the vasoconstriction the drug causes. The thromboxanes act as stimulants of platelet creation and platelet aggregation. By inhibiting these lipids, you will bring down your risk of clotting somewhat.

But it can take a little while for aspirin to start having this effect, and at the same time you are continuing to push your cardiovascular system too hard. That vasoconstriction is still going to be there which will put you at a larger risk for a clot related event, and it already sounds as though you are doing yourself serious harm or on the verge of it.



Do you mean glycogenesis or gluconeogenesis? The former is the synthesis of glycogen from glucose, and the latter is the production of glucose from non-carb sources. Or do you just want your body to produce more energy from your food? If that's what you want, I'd recommend some low GI foods so that you don't burn through it all too quickly.

Are you eating healthy already?

Also, magnesium can help with muscle tension. Magnesium supplements are good for this purpose, I've seen BL'ers recommend them for MDMA 'gurning' before.

Yes. Eating. But need MORE energy.

 

[Mr. Squiggle!]

^^
Omega point, you're setting yourself up for one shitty situation.

Get some rest, the main guy from Spun above me.

Don't you stupid fucks know the risk involved when one ingests large amounts of D-Amphetamine?

Heart Failure, Stroke, Aneurysms, as well as the mental POV, psychosis, temporary and permanent, depression, neurosis conditions.

 

[omegapoint]

I had a mate eat his whole bottle once.

I'll tell you this, If you have ever questioned the purity of your drugs based on subjective effects - 500mg of pure d-amp will do the trick to making you feel like you're having a heart attack for 3 days.

If 500mg of the meth you're getting isn't doing the same - I think we have a problem

I am an IDIOT doin what I am doin but 500m d-amp is F' up and should never ever be attempted. omg...

Thanks lagger and Mr.Blonde...

Any info on d-amp and kinetics with relavence to mitochond and ATP???

 

[omegapoint]

^^
Omega point, you're setting yourself up for one shitty situation.

Get some rest, the main guy from Spun above me.

Don't you stupid fucks know the risk involved when one ingests large amounts of D-Amphetamine?

Heart Failure, Stroke, Aneurysms, as well as the mental POV, psychosis, temporary and permanent, depression, neurosis conditions.

MY PROBLEM IS:

1) Allergic to Benzodiaz ET.AL. No alpraz, clonaz, diaz....

2) Can not drink

3) NEEDING D-AMP TO SLEEP AT THE MOMENT DUE TO PARADOXICAL REDUCTION IN BP AND OTHER EFFECTS: ie my prob is if and when I have/do stopped I get BAD cardio etc THEN...

Need to REDUCE but whilst doin so: what can I use/take to help: cardio, twitches, electric-static-skin etc ???

Psych=FINE/OK (maybe bit 'slower' only as physical sympts predominant consciousness.)

Thanks.

Any ideas now???

Mr.Blonde: what about PH effects of Acetylsalicylic on d-amp, stomach, urinary, metab ???

ie: not COX/Th but other blood and metabolic effects???

Could Aspirin CAUSE more problems than its worth???

Maybe propanalol... Clonidine...

Want to try SEREQUEL which HAVE HERE but it causes ARRHYTHMIA no??? use as D1/D2 antag.... and Alpha/Beta ??? It also does 5ht/NE yes???
Anyone know why under LEFT ARMPIT? Feels like pulsing/harder etc like "bubbling" in vein/art. ??? Had for years. Just HARDER on d-ampx.

 

[omegapoint]

Figured it out.

Completely straight now - and def no psychotomimetic sympts at ANY stage!

Main culprits: ME, INSOMNIA, and----------> Nature's Own "covert" CAFFEINE.

CAFFEINE on D-AMP no good ! (No shit, LOL.)

It was Caff contained in, of all things, Nature's Own MULTIVITAMINS (registerered TGA product sayin MULTIVITAMINS on back ONLY) but which contained CAFFEINE etc (and other "herbs" with such - gingko, ginseng, etc etc etc. but this info NOT ADVERTISED ON FRONT OF PACKET). These were NOT mine and thus I had not read the back. Asked for packaging from friend and soon as clicked to CAFFEINE etc I stopped these and was able to that night sleep. After that still had bit of d-amp/para-metabols in system so used Methadone and fine now. But yes - the one thing other than Caff was:

I could not sleep because of BRAIN ZAPS (ie: SSRI Withdrawl Symptomology) and was caught between being "awake" exhausted unable to look at ANYTHING (eyes sore) and between falling asleep only to get to 30 seconds eyes closed then ZAPPPP!. Anyone know how to get rid of/prevent such zaps?
Is it 5HT depletion? Will Tryptophan/5htp/etc work? B6? Maybe an SSRI post-dex-use to recover such? Wanted to try Tramadol but couldnt convince myself as NE-stim wouldve maybe pushed me over the edge.

THANKS.

PS: anyone ever tried AMPs with supplemental ATP ???

 

[Christ!]

omegapoint - Sorry I can't help you out more directly dude. Just wanted to mention to be careful with supplements while using meds like Dex (you probably already know this )

Any caffeine with d-amp is bad news in my experiences! Was a big coffee drinker and when I first started on dex I had fair few negative effects...stopped the caffeine and most went away. Nicotine also made me more jittery on dex while before it just calmed me down, relaxed me. On breaks from dex I always go back to the coffee and cigarettes

Tyrosine I find helpful when the dex is wearing off or on days off. If I take it before or during I'll get bad over-stimulation effects though.

dexamphetamine + effexor + caffeine was the worst...massive NE-stimulation. There's a slight risk of serotonin toxicity with any SSRI + stimulant like amphetamine, that risk gets increased if you start going for recreational doses.

http://www.bluelight.ru/vb/showthread.php?t=554189 - here's a thread on reducing SSRI withdrawal symptoms, you might have missed it.

Hope you feel better soon man

Made this post in the other thread but probably more suited here.


Yeah they're definitely tempting if you have an interest in rec. drugs! Recently messed up for the first time and started abusing them...so not worth it. Didn't even enjoy the high. Almost blazed through a script in 3 weeks.

Made me feel sick that I abused them...decided I'm going to tell my psychiatrist since I feel so guilty. He knows about ADD and drugs/addiction so he's pretty understanding. Normally I wouldn't care but he's such a bloody good doctor and really trusts me, despite knowing my addiction history.

To make sure it doesn't happen again I bought a $40 electronic safe from bunnings, it's pretty damn sturdy and could keep pretty much anyone out. My house mate doesn't use drugs and she'll be dispensing them for me daily.

I'm on a pretty low dose of 2 in the morning and 2 after lunch. Tried slightly higher doses but it starts to increase my 'hyperfocus' and end up concentrating on just one thing, often something not that important. I don't take them on weekends and every three months I'll have a break for a week, twice a year I have a break for a month.

For anyone on a 'dex holiday' or dealing with any kind of withdrawal, give tyrosine a try. Makes any withdrawal for me disappear.

 

[omegapoint]

omegapoint - Sorry I can't help you out more directly dude. Just wanted to mention to be careful with supplements while using meds like Dex (you probably already know this )

Any caffeine with d-amp is bad news in my experiences! Was a big coffee drinker and when I first started on dex I had fair few negative effects...stopped the caffeine and most went away. Nicotine also made me more jittery on dex while before it just calmed me down, relaxed me. On breaks from dex I always go back to the coffee and cigarettes

Tyrosine I find helpful when the dex is wearing off or on days off. If I take it before or during I'll get bad over-stimulation effects though.

dexamphetamine + effexor + caffeine was the worst...massive NE-stimulation. There's a slight risk of serotonin toxicity with any SSRI + stimulant like amphetamine, that risk gets increased if you start going for recreational doses.

http://www.bluelight.ru/vb/showthread.php?t=554189 - here's a thread on reducing SSRI withdrawal symptoms, you might have missed it.

Hope you feel better soon man

Made this post in the other thread but probably more suited here.


Yeah they're definitely tempting if you have an interest in rec. drugs! Recently messed up for the first time and started abusing them...so not worth it. Didn't even enjoy the high. Almost blazed through a script in 3 weeks.

Made me feel sick that I abused them...decided I'm going to tell my psychiatrist since I feel so guilty. He knows about ADD and drugs/addiction so he's pretty understanding. Normally I wouldn't care but he's such a bloody good doctor and really trusts me, despite knowing my addiction history.

To make sure it doesn't happen again I bought a $40 electronic safe from bunnings, it's pretty damn sturdy and could keep pretty much anyone out. My house mate doesn't use drugs and she'll be dispensing them for me daily.

I'm on a pretty low dose of 2 in the morning and 2 after lunch. Tried slightly higher doses but it starts to increase my 'hyperfocus' and end up concentrating on just one thing, often something not that important. I don't take them on weekends and every three months I'll have a break for a week, twice a year I have a break for a month.

For anyone on a 'dex holiday' or dealing with any kind of withdrawal, give tyrosine a try. Makes any withdrawal for me disappear.

What is minimum HOLIDAY to get Tachyphylaxis effect and Tolerance down/reset ?

Sure. Will DEF try Tyrosine... Cheers.

IT is hard to stop to nothing but fact is do not get a high now - except physical symptoms - and bit more phys ability as actual energy (not high) pretty much NOTHING.

Dont really understand TOLERANCE/TACHYPHYLAXIS happening *NOW* as have done WAY worse/longer binges: why would I become tolerant/tachypyl to d-amp now and over this period (3 weeks) and not 3 months usage of other phenethylamines etc? Particular pharmaco-chemistry of dextro? Particular usage/dosage? Even with food and sleep being reasonable... Just wondering...
I know what you mean about HyperFocus and other things not important: ie HKLM in reg LOL.

No jellyfish in that sewer though bro - well, have not looked yet, but I DONT BELIEVE IT HA :D.

[snip]

Thanks.

I went through 12 bottles in about 2-3 weeks once.
I managed to rack myself up huge credit debts i cannot pay off due to buying shit online!
Very obsessive shit. I also lost about 20KG lol. and in the second week the only trhing that would put me to sleep were about 20+ dexxies.

DO NOT TRY THOSE DOSES WITHOUT TOLERANCE.. or at all really....

Dex effects on 5-ht and ParaHydroxy-metabolites: threshold both approx 3 weeks I believe...

(I know it is generally NOT 5-ht aganosit but I have crossed that line now I think... ? Is there a specific one-off dose that would cause 5-ht agan. or is it only over period of time ? Any known "mean" mg dose for 5-ht response or Direct Release DA/NE ?)

Hi. .

Just wanted to ask:

1) Anyway to combat Tachyphylaxis of d-AMP ?

ie: when getting physical sympatho but no psychological effects non-dose-dependant...

Tyrosine? Phenylalanine? .... I am sleeping but using daily d-amp in divided doses. not doing enough mentally but full on physical symptoms... strange... I AM sleeping.

Difference between Tolerance and Tachyphylaxis I think...

Any thoughts?

2) Are BRAIN ZAPS 5-ht withdrawl/depletion? ie: Dex gone so 5-ht down (see above.) ?

3) What ARE Glucogen and Glycogen and ATP effects of taking Dex?

 

[Mr Blonde]

2) Are BRAIN ZAPS 5-ht withdrawl/depletion? ie: Dex gone so 5-ht down (see above.) ?

3) What ARE Glucogen and Glycogen and ATP effects of taking Dex?

2: I think so. In SSRI WD I believe it is due to the brain decreasing serotonin production in response to an increase of extracellular levels of serotonin, as well as the down-regulation of serotonin receptors.

3: Amphetamine decreases glycogen levels, I can't find data on effects on glucagon (which is what you mean instead of glucogen) and according to a few abstracts I just looked at, amphetamine increases levels of nitric oxide which apparently depletes levels of ATP.

1) Anyway to combat Tachyphylaxis of d-AMP ?

Tachyphylaxis? As in, decreased response to the drug due to long term exposure?

There has been some research into NMDA antagonists possibly helping with tolerance, and there have been some posts on websites about using magnesium for this purpose though I am unsure as to whether the action magnesium is having is actually tolerance reduction as opposed to increasing bioavailability.