Nice thread.
On ayahuasca, I recall being completely perplexed by my hands. So strange looking at them. That trip was several years ago, so my remembrance of the exact feelings I had is a little foggy. I think I remember the sensation of seeing a 'hole' within them. My perspective of them was radically changed because of the space-time warps caused by high dose psychedelics.
On DOC, the effects were much more dramatic. Looking at my hands was like looking at a holy object. I remember falling into a trance, and my environment proliferating in complex, symbolic, colorful ways. It was kind of like entering an utterly different, timeless, ancient landscape.
I think the hand is a fascinating symbol. I was hiking in a canyon in Colorado last weekend and saw some beautiful petroglyphs of hands; a reoccurring theme in many different cultures, to be sure.