I made this multi to answer Pegasus question since my temp ban ends on Jan 19 2011. The admin knows me so I'm sure he wouldn't mind. Happy new year bluelight! ^.^
Ok, cold water extraction. The thing is, If you use 150mL to do the extraction you'll get a lot more than 50% yield, in fact your yield will be close to 90%. The way it works is that we consider Tylenol powder as spherical particles of a certain size and each particle has to fully dissolve in water in order to maximize codeine output. The particles are porous so some of the codeine is able to exit the particle without the particle dissolving completely but as the channels start to get smaller, the water has more trouble penetrating the particle due to the hydrophobic Tylenol content.
If you use 150mL to extract 15x 500mg pills you don't have to worry about heating up because your dissolved Tylenol will be 0.75g/100mL times 1.5 100mL = 1.125g
And 1.125g / 15x 0.5g = 15%
If you're above 10% you're ok. However, if you're below 5%, even if you shake it for 4-5 minutes you will have a considerable codeine fraction that will remain trapped inside. This is only with small volumes of water and large masses of pills, such as using 15 pills in 20mL of water. The percentage in this case is 2% so the final disolved Tylenol will be 150mg, which is a very small amount to swallow. In this case, if you use 20mL of icy water with 15 pills I guarantee you that you'll get 50% yield.
However, there's an easy way to bypass that, by playing with temperature. We know that temperature is a kinetic factor and so, increasing the temperature of a saturated salt solution will increase the saturation point. Instead of having 0.75 mg/100mL, if we heat to 75 degrees Celsius, the solubility becomes around 5g/100mL so our new % is [5g x (20mL/100mL)] / 7.5g = 13%
The percentage is now in the safe region so we know our yield is above 85%. I have personally experimented with this and even made a table in my previous posts somewhere. This is the step where codeine is released. Once it is released, you no longer need the Tylenol to be dissolved so you can cool down to freezing point and extract the solution.
Rule of thumb: Small water volumes + large pill # = you have to heat. Similarly, large water volumes + small pill # = use icy water.
I hope this clarifies ^.^
laterz[/QUOTE]
Hi man.I made a cwe with 17 large pills(paracet.500 and codeine 30mg).I used a small amount of cold water(not from the fridge,but cold enough) and 2 wet coffee filters.I crushed the pills in an almost fine powder.I stir the solution and i filtered it.It didn't make a long time.Then i put some little water in to the grab to take the codeine that might had remaine.My final solution was very clear,i drunk it,but i didn't feel anything.You think that it was cause of my very big tolerance(I use 100mg pathces for 7 years and h),or i did something wrong in the cwe?Please answer if you like,cause i think that you know a lot for the cwe(sorry for my bad english,mate.)
