4DQSAR
Bluelighter
- Joined
- Feb 3, 2025
- Messages
- 6,258
What is the tremendously long half life that you say it is?
Well, it seems to vary hugely. While 24-49 days is cited in a few places, J&J state that discontinuation can take up to 126 days. But some NHS foundations suggest upto 18 months.
That's why I asked if people needed to be prescribed the depot formulation or could at least some of them simply take an IR formulation. Or if that's not available, would the parent drug rispiridone (which is quickly metabolized into paliperidone) be an alternative?
