Mental Health Coming Off Invega Sustenna (Paliperidone) v4

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"What can pass through blood brain barrier?
The blood-brain barrier restricts the passage of pathogens, the diffusion of solutes in the blood, and large or hydrophilic molecules into the cerebrospinal fluid, while allowing the diffusion of hydrophobic molecules (O2, CO2, hormones) and small polar molecules."

Can this be because we can't get affected by substances? blood-brain barrier is blocked or something like that?
 
"Pharmacological blocking agents are an important treatment approach for the current epidemic of drug abuse. This approach is multidisciplinary, ranging from molecular neuroscience for developing these blocking agents to behavioral therapies for establishing treatment delivery systems. This paper outlines the biological, behavioral, and clinical components of the pharmacological blocking agent approach. Clinical results using two blocking agents, naltrexone for opioid abuse and disulfiram for alcohol abuse, are reviewed as a source of leads in developing potential agents for treating sedative and stimulant abuse. While specific pharmacological antagonists have been developed for benzodiazepines, such agents are not yet available for stimulants. Furthermore, the clinical utility of stimulant antagonists may depend on the development of multisite agents that partially block several neurotransmitter systems rather than target a single-system brain receptor. "

So our neurotransmitters are blocked by invega.
 
I’m at 10 months off of one invega shot (234mg). it just feels like my brain has been reconstructed but not in a good way. It feels like parts of my brain are missing. I’m not social at all, feel really dumbed down, struggle to access memories I once had Etc.
If i was you, i would go for nutritious dense foods and long fasts.
 
Check Ekbr its a profile on doctissimo website its a beautiful story of recovery she was injected 7 years ago and recovered in 3 years its the only one i trust
 
she start smoking weed at month 7 when she came back to school she said the first year was horrible and she wanted to kill herself, she couldnt take a shower...
 
She told me weed helped to recovery thoughts and to feel the tension in her body. But it mostly all the efforts she made to have a notmal life that helped her ( meeting people...)
 
Ekbr:
Hi Guys, I often get messages from people among you who have been affected, for one "reason" or another, by the plague called neuroleptic, and you ask me if I got through it, and how, etc. ...
So I come to the news :)
To begin with, I will give you a bit of my take on this whole impasse.
Already a few words on my case: the disaster, the annihilation of my life, were signed by Mr Xéplion, available as an injection 150 + 100mg to put according to your affinities in the shoulder or in the buttocks, for a business, in your buttocks therefore, around € 500 per injection.
Well. I weighed 50kg, in the space of a week I was put directly into the muscle the equivalent of a month's dose of 8mg / day of Risperdal, as much to tell you that very quickly, simply remind me of my first name has become difficult.
So I lost all my friends, all my passions, I stopped everything, in fact I went back to my parents to stay in bed for an average of 22 hours a day for endless months.
So what happened is that at first I took it quite a bit because these wonderful doctors told me that it was a necessary step for my recovery and that everything was going to fall back into place.
However, I was really lethargic and did everything to stop this poison as quickly as possible. And I thought all of my energy was going to come back instantly as soon as the poison was cleared from my body.
I was told it was a month or two for the body to get rid of this. Well, I quit in March 2014 and nothing really changed for a very long time.
So what can I say? The brain is not just like a bladder that you fill or empty. Even if the bladder has all its complexity, the brain tissue is really of a different nature compared to all the organs: it is an embryonic tissue that changes every moment, that continues to evolve, potentially life-changing dramatically.
I think a poison like the neuroleptic infertilizes that poor brain for a while. A bit like if you were spraying round up in your compost ... It will be pretty pooh. And the reality is that even if you stop vaporizing, it will take a while for this soil to become ideal for seeing your small organic tomatoes grow!
Keep this in mind: you have within you, a capacity that you do not suspect, an energy that can allow you to overcome it all, to become stronger than this shit that they are trying to kill you with nicely.
But know that it is a force that very few people are brought in their life to find - quite simply because they never reach this level of difficulty in life.
You will start to be shocked to see people who have not received this poison complain that they are tired, happy, or anxious.
You will be shocked by the fatigue of others because you will rethink the difference in energy between before and after the poisoning and will not conceive that a person who has not been infected knows what they are talking about when speaking about fatigue.
The happiness of others will make you barjo because you yourself will feel absolutely nothing and will pass for an autistic.
Finally, you will come to envy the anxieties or panic attacks of others by saying to yourself, "Heaven, his guts are talking to him, where are mine"?
So, let's get to the point, what is this magic formula to find this fabulous force that will allow your brain to come back to life again?
1 / you are going to stop being anxious to be "like before" again because it generates frustration in you, but the kind of toxic frustration where you spend your time feeling sorry for yourself and disgusting yourself - even.
In fact, if you want me to expand a bit, consider that coming back to yourself will be your bohemian kid who never-never knew a law. The reality is that by the time you feel fully yourself, it will be a long time since you stopped asking yourself this question.
2 / you will stop being ashamed of your history room because no, you are neither stupid nor damned.
3 / you will leave the role of victim, preferably before it stinks your whole life and if not, too bad, you will have to rebuild yourself.
=> a key idea in all this: this unfathomable tissue of your brain is sensitive to the nature of the image you have in yourself, of yourself, of life.
Hope I enlightened people, please feel free to send me your questions, I will be back!
Peace
 
why i trust her ? Simply because she uptated all her recovery and describe the feeling so well
 
Hello, Bluelight! Just created an account to participate in the Invega Sustenna discussion.

I've recently gotten on the shot and yes it really blows! Not as bad as some of the heavy complaints (but everyone's experience is different and I do NOT discredit that) - but still, it's damning enough to be warranted as a "last resort" treatment rather than the first measure.

I have many more shots to complete before the doctors will let me go.
I have been trying to switch to Abilify, as it has a much better effect profile, right?

I will be getting Saint John's Wort and using it everyday.
Hopefully it will let me get a bit of effect of caffeine, etc!
Maybe someone can weigh in, if I am even going to do so?

Anyways, I won't bother much more room here - just waiting to get off of the shot as I was misdiagnosed.
Had a ragequit in the psychward six years ago and they just reopened my file without giving a second evaluation.
Call me bipolar when I have the calmest demeanor I have ever seen, and schizophrenic when I understand esoteric ideals.

I'm stunned that my amphetamine-like compounds have NOT A SINGLE EFFECT and I can take SLABS of caffiene pills with NO EFFECT.
Jesus Christ! Not like I want to escape reality, I just want to IMPROVE MY PERFORMANCE. I really hope the 'Wort can help with some of it!

I do know, however, that I can get a smidgen out of propylhexedrine, but I have to double the dose.
Speaking of double-doses, I have had fire MDMA (and it WORKED) but I had to dose like 0.5g+ <3

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EDIT // I may likely make a new account once I decide a name that isn't so whack lmao (can't change it).
This is coming from a year of research and not personal experience, but abilify is no better. It seems like its makeup would allow it to block less but it still has significant dopamine blockage, with an increased rate of akathisia and perhaps less sexual side effects. I too didnt think invega was so bad until about two weeks in, when my brain fell out of and rejected lifelong memory and comfort patterns due to lack of reward. Dont play the round and round the medication carousel game. It's the only game the psychs know how to play, and they are not honest. They will never get you off of it. They will just move the goalposts a year in. In their eyes, you are a damaged danger to society for life, and they are keeping everyone safe. The medication ensures that you will remain damaged.

My psych told me I would kill my kids if I got off invega, because the second episode is so much worse. This was a lie and a manipulative scare tactic.
Thank you so much. I wish i could think of something else besides how bad this is!!!! Can you cry? And if so, did you cry a lot when able?
I also couldn't think of much else. I was on this forum every day. I had to stop talking about it, because my family got really tired of me saying how much It was affecting me. No one can understand it or believe it unless they've gone through it.
 
Did the feeing when you woke up diseapered ? brain zap that almost paralyzed u?
Yes, I would get that feeling before I went to sleep and I could not sleep when on invega. I could at least sleep a little after a couple months and returned to a regular sleep within a few months. At 2 years I can enjoy taking naps again.
 
Yes, I would get that feeling before I went to sleep and I could not sleep when on invega. I could at least sleep a little after a couple months and returned to a regular sleep within a few months. At 2 years I can enjoy taking naps again.
How’s your social life now that you’ve recovered?
 
How’s your social life now that you’ve recovered?
It's alright. I have a lot of social damage from the psychosis itself and some self-worth issues in that regard. I've had some people I thought I was very close to throw me in the trash. There's no one lower on the social totem pole than the "mentally ill" or those perceived as such. But the few close relationships that are still open have been regenerated, and things are great with my husband and the new people that I've met. I've formed new and close relationships. I can stay up all night talking and laughing on occasion, and I have a desire to spend time with people and to share my ideas. Invega no longer has any effect, it's more of just dealing with the aftermath of a life blown up by two psychotic episodes.
 
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