Mental Health Coming Off Invega Sustenna (Paliperidone) v4

[level_select]

Hopton09 - you'd be better off adopting a more positive mindset. The placebo effect applies to the brain too:

"Strong placebo responses have also been linked to increases in dopamine and opioid receptor activity. Both of these chemicals are involved in reward and motivation pathways in the brain. Conversely, nocebos have been found to reduce dopamine and opioid receptor activity."

Placebos: The power of the placebo effect

The placebo effect is a phenomenon in which the body starts to heal even if it only thinks it is receiving treatment. The effect is mysterious, pervasive, and clinically important. Here we discuss what it is and theories as to how the placebo effect works, as well as the possible clinical uses...

www.medicalnewstoday.com

 

[t_xeplionhell]

Hopton09 - you'd be better off adopting a more positive mindset. The placebo effect applies to the brain too:

"Strong placebo responses have also been linked to increases in dopamine and opioid receptor activity. Both of these chemicals are involved in reward and motivation pathways in the brain. Conversely, nocebos have been found to reduce dopamine and opioid receptor activity."

Placebos: The power of the placebo effect

The placebo effect is a phenomenon in which the body starts to heal even if it only thinks it is receiving treatment. The effect is mysterious, pervasive, and clinically important. Here we discuss what it is and theories as to how the placebo effect works, as well as the possible clinical uses...

www.medicalnewstoday.com

I somehow feel better every 10 days.

 

[Hopton09]

Hopton09 - you'd be better off adopting a more positive mindset. The placebo effect applies to the brain too:

"Strong placebo responses have also been linked to increases in dopamine and opioid receptor activity. Both of these chemicals are involved in reward and motivation pathways in the brain. Conversely, nocebos have been found to reduce dopamine and opioid receptor activity."

Placebos: The power of the placebo effect

The placebo effect is a phenomenon in which the body starts to heal even if it only thinks it is receiving treatment. The effect is mysterious, pervasive, and clinically important. Here we discuss what it is and theories as to how the placebo effect works, as well as the possible clinical uses...

www.medicalnewstoday.com

I absolutely do not believe that. There is no placebo in the world that reverses actual physical brain damage

 

[Hopton09]

I just read you're four months off? I would say you have to give it more time. At four months, the drug is still in your system (albeit at a much lower dose).

The people that actually recover feel better by 4 months. Things are getting worse. My ability to get high literally is only getting worse. I used to be able to feel kratom after the shot. Now it doesn’t work at all

 

[level_select]

I'm sorry to hear that you're feeling so bad. I don't do any drugs on a regular basis, so I don't know what it's like to miss getting high that much.
I tried ecstasy once when I was younger though and I did crave it afterwards actually, but I stopped craving it after about six months because I didn't do it again.

My advice to you is still twofold - give it more time and try to adopt a positive mindset. If you can't, just give it more time. There's no reason for you to believe you won't recover.

 

[level_select]

absolutely do not believe that. There is no placebo in the world that reverses actual physical brain damage

I don't know if Invega directly causes any brain damage, I think it might cause a very small amount over time, but I'm not sure. I don't think it damages the dopamine receptors though. If anything, I think it's more likely to cause a very small amount of atrophy because of a lack of stimulation, but I'm not sure where or how much. And I think that this is 100% reversible, because the brain knows how to regrow and repair itself. It's very good at this. You should google neurogenesis. I strongly believe that your mental outlook has a very real physical effect on your cognitive functioning too.

 

[Hopton09]

I'm sorry to hear that you're feeling so bad. I don't do any drugs on a regular basis, so I don't know what it's like to miss getting high that much.
I tried ecstasy once when I was younger though and I did crave it afterwards actually, but I stopped craving it after about six months because I didn't do it again.

My advice to you is still twofold - give it more time and try to adopt a positive mindset. If you can't, just give it more time. There's no reason for you to believe you won't recover.

There is all of the reason in the world to believe that I won’t recover

 

[level_select]

Well, that hasn't been my experience.
I just hope that you can get through the next few months, because I believe that you will feel a lot better.

 

[Hopton09]

Well, that hasn't been my experience.
I just hope that you can get through the next few months, because I believe that you will feel a lot better.

I do not expect it. I’m not getting my hopes up and having them crushed when I’ve seen enough evidence to know better. I’ll simply suffer until I can’t take it, and then I will find a gun and I’ll put a bullet in my head. I don’t belong on this planet

 

[Bigsmoke420]

Why don’t you message the guy who created this thread and see if you still don’t believe it causes brain damage. Come on man that’s being so blind to the facts. Look at all the freakin people who never recover or never get high again. It isn’t just the drug being active. It’s way way after it’s out of the system. It absolutely damages the brain……severely.

Stop Spreading lies.

 

[Bigsmoke420]

I do not expect it. I’m not getting my hopes up and having them crushed when I’ve seen enough evidence to know better. I’ll simply suffer until I can’t take it, and then I will find a gun and I’ll put a bullet in my head. I don’t belong on this planet

You have your opinion and that's fine, but dont going saying these things are facts. People do recover, I'm sorry that your not one of the ones who didnt. Not everyone recovers.

 

[n3ophy7e]

I had a psychotic episode because of something bad that happened to me and my girlfriend at the time. I was using weed, Kratom, and Coca back then. The doctors are fags and labeled me a drug induced schizophrenic, disregarding the horrible situation I was in that led to me losing it.

My plan is to also use a whole mixture of drugs in a few months when I’m off this garbage to reset my brain function.

Just a couple of things: Please refrain from using the word "fag" as a derogatory term. Also, it's not a good idea to use a bunch of drugs to try and reset your brain. That's not how the brain works. You're much better off letting your brain recover THEN trying some drugs.

100mg each time. I am recovering. My concentration is better and my mind is much more active. I'm thinking of writing a blog about my experiences. I've kept diaries and I think it would make a good story. Some of my delusions were pretty funny (and embarassing). I laugh a lot more these days. I laugh when I remember things. I laugh when I tell my friends - I've only recently told them some of the most embarassing things that I thought and did.
I was a very good writer before the shots, but I found that I couldn't write well when I was on the injection. My short term memory wasn't as good and I didn't have the imagination for it either. My writing is better now, but I wouldn't say I'm fully recovered yet. I'm still not as creative. Yesterday, I wrote 4000 words.
Although I had the concentration for reading when I was on the shots, I didn't have the motivation for it, but now I'm reading novels when I go for walks again (I read as I walk with my kindle in my hand). Also, when I was on the shots, I would sometimes just play snake on my phone all day (depressing days!!!), but I'm reading more and thinking about things more now. It's easier to clean my house and I listen to music every day. I'm also feeling much more motivated to get my life together and I've joined dating apps too. I wasn't at all motivated to do this when I was on the shots.
I've struggled a lot with insomnia over the past month, which I know is withdrawals, but I slept for 7 and a half hours last night, which was good. I still don't have the motivation for running, but I'm going to try to force myself tomorrow. I want to lose the 15 pounds that I gained on Invega (I actually gained 20, but the first 5 have already gone).
I think I will recover my imagination and motivation in full, but it may take a few more months.
I think your ability to feel dopamine and seretonin returns in full when the drug is out of your system, but I also think that the drug can damage your brain in other ways. However, I also know that the brain is self healing. I focus on the recovery stories. I suggest you do too.
I consider myself lucky to be off the injection now. I feel so sad for the people who are still on it and will be put on it again in the future, especially now they have the 6 monthly injections. It's nightmarish. I hope my writing will help to raise awareness of mental illness, psychosis, the realities of antipsychotics and alternatives to medication.

That is so awesome, thank you so much for sharing your experience with us A lot of people in this thread rely on stories such as yours to give them hope about their own recovery.

So in other words you still can’t get high. That doesn’t sound like being able to get high to me. It would be exactly as it was before the shot and no doubt about it

I have already warned you in this thread about being disrespectful to other people's experiences. I am going to start deleting your posts that are directly disrespectful to what people have to say.

 

[Truthvega3456]

Has anybody thought about taking Wellbutrin to help with dopamine and prolactin. My doctor brought it up. I think i wanna try it but I also want to wait till I turn 21 and smoke some cigarettes

 

[n3ophy7e]

Has anybody thought about taking Wellbutrin to help with dopamine and prolactin. My doctor brought it up. I think i wanna try it but I also want to wait till I turn 21 and smoke some cigarettes

Interesting. Why do you wanna wait until you smoke cigarettes?
Oh and yeah in theory it could definitely help.

 

[plumbus-nine]

Fuck it's sad that the coming off antipsychotics thread(s) are among these with most postings around this platform and I guess we'll continue seeing stuff like this for the meantime. While science did a solid job in catching up during the latest decades, they continue to apply theories which more or less prove wrong, like the dopamine = bad shit.

@Truthvega3456 Wellbutrin, when orally taken as recommended, is almost entirely a noradrenergic with some weird sides like that it seems to mess with glutamate a bit but it's only dopaminergic when insufflated (tried it; can't recommend because besides the fillers in pills you'll get 45mins up and 8+ hours down as these metabolites, which make up the intended therapeutic effect but feel dysphoric when one has developed dopaminergic tachyphylaxis before, last an awfully long time).

I'd rather recommend to give memantine a try, it was even trialed in people with diagnosed schizophrenia (in combination with antipsychs to counter their side effects but still) and is a very safe substance at least for the category it fits into, as a D2 dopaminergic agonist and NMDA antagonistic dissociative. In lower doses you primarily get the nACh antagonistic effects (transient; some get mild brain fog, others not) and dopamine agonistic ones.
Wellbutrin also only blocks nicotine during its own half life, after it's out you'll "feel" cigs again. Drug effects tend to be non-permanent.

For prolactin the medication of choice are dopamine agonists, just good luck getting a doc to prescribe them, maybe pretending RLS would be the best chance - I get more and more comfortable recommending these two as I couldn't find any real prove for that dopamine was the culprit among psychotic disorders but a bunch of opposite evidences as my personal trial of a few agents when I had some so-called positive symptoms before - this applies solely to people with drug induced or affined problems, endogenous psychosis might be a different game.

 

[t_xeplionhell]

The people that actually recover feel better by 4 months. Things are getting worse. My ability to get high literally is only getting worse. I used to be able to feel kratom after the shot. Now it doesn’t work at all

You might developed tolerance.

 

[t_xeplionhell]

I do not expect it. I’m not getting my hopes up and having them crushed when I’ve seen enough evidence to know better. I’ll simply suffer until I can’t take it, and then I will find a gun and I’ll put a bullet in my head. I don’t belong on this planet

I thought the same until I saw progress and no more 0 dopamine and serotonin (still bad amount but noticable improvement). I thought that I cant endure more after just 1.2 month and here I am 2.6 month after doing much better than at 1.2 month off. Days passes by much faster. I suggest you try my method it scientificaly proven that it helps body to remove invega from receptors.

 

[apsucks]

I do not expect it. I’m not getting my hopes up and having them crushed when I’ve seen enough evidence to know better. I’ll simply suffer until I can’t take it, and then I will find a gun and I’ll put a bullet in my head. I don’t belong on this planet

At least you had one injection i still have to get a few.....another couple of months wasted before recovery

 

[t_xeplionhell]

At least you had one injection i still have to get a few.....another couple of months wasted before recovery

I think he had 2.

 

[apsucks]

I did recover, albeit with prolactin issues which I know affected me in all ways bad.
But I was able to get high on H, and k2, slightly on Hash, and meth would wake me up and give me energy.

On the shot weed is pretty dysphoric and rather confusing