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Mental Health Coming off Invega (Paliperidone, Xeplion) injections v. 7.0

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Rulomaner said:
We dont know what happened. We dont actually know how this drugs can modifie the receptors and its proteins…
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There were many researches on how antagonists can modify protein receptors, it's shown that they over longer exposure (weeks), gradually deform the protein or break it, making it work less efficiently or not able to receive transmitter chemicals.
 
So I was able to get sad that a coworker was leaving my job yesterday and also I'm able to fake laugh in conversations. Thats all I contribute to convos tho Im otherwise a mute and cant really talk all that well.

I drink every now and then and feel no euphoria. I get a little more talkative though. It lasts only 30min or so. Last time I smoked I got high af but that happened straight off fresh shots so I think weeds the only thing that works even on invega. Imma stay away from it tho since I got my psychosis due to it. Was a heavy smoker since I was 16 or so. A decade of heavy chuffing.

Tbh all I want is my body back. I worked out everyday for 3 hours no cardio all weights cuz I was a hard gainer. I trained everyday for 7-8 years and was competeing in bodybuilding shows in hopes to get a naturals pro card. Now I dont workout cuz results were slowly turning negative( was getting fatter and fatter regardless of training and weaker regardless of weighing more). The only desire I have is to be skinny again. Now I weigh 90kgs or 200lbs and look like Juice wrld. Pre invega I was like 165lbs when absolutely peeled and shredded and like 172-180 during off seasons. Id like to be like 150 or so like my pre gyming days now that I Ive given up on training. My logic is since I had a lot of muscle which I slow bulked up to for 8 years I should be alright at 150 with less muscle. Ill pick up on gyming once I know I can continue making progress again.

This is the most important thing for me. It may sound pathetic but my looks were what allowed me to have confidence and have a good life. I was able to get into nice relationships communicate with strangers and friends. Make new friends and just be myself without shame. I used to think I was beautiful and felt like no one could belittle what I had accomplished. Now Im suffering from being over weight and my face has changed drastically. Where as before I could just strike conversations or have people approach me on the street now I feel no one wants to talk to me. I feel disgusting and have 0 confidence now. If my exes saw me theyd be ashamed lmao.

I love juice since he got me through hard times but I always was like damn this man has the worst genetics and looks jiggly af.

Last shot was a shot of trinza on june 6th so Im still waiting for the first half life to end. Everything else aside from looks is secondary to me. My emotions are somewhat present and have improved slighty since the shot
 
Euphoria is a very biased word. It can have different meaning to someone. Use specificity or plant seeds of uncertainty, you pick.
 
t_xeplionhell said:
There were many researches on how antagonists can modify protein receptors, it's shown that they over longer exposure (weeks), gradually deform the protein or break it, making it work less efficiently or not able to receive transmitter chemicals.
Click to expand...
Do you by any chance know what Invega Sustenna does to myelin?
 
I know it's physically hard for everyone's brains to feel optimism right now, I get it, but holy shit. I'm not going to be hanging around here. I've been looking at these threads for a while and I think it would just hurt me. I guess I'm lucky because I can still feel emotions to a degree and I have a good doctor.

You guys are probably going to be ok. I'm going to get on Viibryd instead of escitalopram because after doing more research on how these drugs work, I think invega fucked up my response to SSRIs and I need a partial serotonin agonist to avoid the anxiety gap I'm experiencing. It also doesn't cause sexual dysfunction, it's pretty much the only SSRI that doesn't.
Try to uplift each other. I know I'm recovering. You might hit a hard point when your adrenergic receptors turn back on, you will be filled with fear and anxiety without the brakes of serotonin. But that means it's getting out of your brain. Buspirone is helping me with this anxiety, I just got it last night.

I know everyone has been traumatized by big pharma or whatever, but there is stuff that can help you guys out there. Talk to your doctors.
I'm outta here, I'll come back with updates and for any replies I should attend to. Dwelling here can really hurt you, I think, especially if you're mentally ill. Look up coping mechanisms for disassociation, y'all are disassociating on top of having your good chemicals blocked, and that makes you feel even more numb. I know this drug causes disassociation. I've felt cut off from myself before, I have depersonalization/derealization disorder, and this drug has caused the worst disassociation episodes of my life.

I've been going for walks, taking showers, and swimming around in my little pool in the back yard. Talking to my friends also helps. Being around people is good for disassociation too, have someone engage you.

I rejected help at first too. Please, seek help everyone. It's out there, I promise. I know it's hard but you need to try. The thing that has helped me the most is seeing what I can do to help myself recover. Peace out.
 
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Dont make me laugh dude. It has been 6 months living with abilify injection inside my body and I can tell you that suicide is the most suitable word to describe the feeling. Not even in my bed I can feel pleasure. Its not only emotions. Its pleasure. Its satisfaction. Its calm. Its been at peace. And I am not able to be at any of those states since I got this piece of shit inside of me. I am not disassociating bro, I am suffering for my life.
 
Rulomaner said:
So how do you think a protein can be healed from that damage, taking into account it can…?
Click to expand...
Talk to your doctor bro seriously. Information on here is not reliable.

I’m almost five months off now and can enjoy my vacation just fine. It’s not like a rollercoaster but I can enjoy seafood, good wine, barbeques, sunshine and beach, liquour has some effect. What am I missing? Right now I feel amazing lying by the pool. I spend time with friends and enjoy their company. We go to bars and clubs with live music and such.

Fuck invega don’t let it mess up everything. Get out of the apartment nothing worse than sitting inside when the weather is good. Treat yourselves tou deserve it
 
InvegaAnon said:
I know it's physically hard for everyone's brains to feel optimism right now, I get it, but holy shit. I'm not going to be hanging around here. I've been looking at these threads for a while and I think it would just hurt me. I guess I'm lucky because I can still feel emotions to a degree and I have a good doctor.

You guys are probably going to be ok. I'm going to get on Viibryd instead of escitilopram because after doing more research on how these drugs work, I think invega fucked up my response to SSRIs and I need a partial serotonin agonist to avoid the anxiety gap I'm experiencing. It also doesn't cause sexual dysfunction, it's pretty much the only SSRI that doesn't.
Try to uplift each other. I know I'm recovering. You might hit a hard point when your adrenergic receptors turn back on, you will be filled with fear and anxiety without the brakes of serotonin. But that means it's getting out of your brain. Buspirone is helping me with this anxiety, I just got it last night.

I know everyone has been traumatized by big pharma or whatever, but there is stuff that can help you guys out there. Talk to your doctors.
I'm outta here, I'll come back with updates and for any replies I should attend to. Dwelling here can really hurt you, I think, especially if you're mentally ill. Look up coping mechanisms for disassociation, y'all are disassociating on top of having your good chemicals blocked, and that makes you feel even more numb.

I rejected help at first too. Please, seek help everyone. It's out there, I promise. Peace out.
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No one here is mentaly ill. How can you even have the audacity to accuse people suffering from AP damage of mental illness? No amount of pills is gonna repair this cause it's caused by brain damage. Also, dwelling here is harmless. We're here because we're miserable, not the other way around.
 
Baddream said:
Talk to your doctor bro seriously. Information on here is not reliable.

I’m almost five months off now and can enjoy my vacation just fine. It’s not like a rollercoaster but I can enjoy seafood, good wine, barbeques, sunshine and beach, liquour has some effect. What am I missing? Right now I feel amazing lying by the pool. I spend time with friends and enjoy their company. We go to bars and clubs with live music and such.

Fuck invega don’t let it mess up everything. Get out of the apartment nothing worse than sitting inside when the weather is good. Treat yourselves tou deserve it
Click to expand...
Man I am 23 years old trust me I have much better things to do than sitting on my fucking bed with no drive for life at all. I have tried sex. Ive tried weed. Ive tried walking. Ive tried socializing with friends. Ive tried eating. Ive tried just walking. Ive tried videogames. Ive tried cigarretes. Alcohol. Ive tried taking a nap. Ive tried everything in my hand to feel happy and none of them give me even the tinyest bit of pleasure to want to do them again. I am happy that you can, but for me its not the act of doing it, its the inner sense of feeling great when doing it, thats what is missing.
 
Well thats what you say amigo. Anyways i am not here to compare myself with yours, im here in order to feel understood and try to find a way out. If you search, you can find abilify antagonizes same receptors as invega, except for the “partial agonism” on DA which in fact is a fraud as it only makes you flat either you have too much or too little dopamine. They call it regulation and I call it torture. If you have too much, let it be too much, I am always flat, as you mate.
 
InvegaAnon said:
I know it's physically hard for everyone's brains to feel optimism right now, I get it, but holy shit. I'm not going to be hanging around here. I've been looking at these threads for a while and I think it would just hurt me. I guess I'm lucky because I can still feel emotions to a degree and I have a good doctor.

You guys are probably going to be ok. I'm going to get on Viibryd instead of escitalopram because after doing more research on how these drugs work, I think invega fucked up my response to SSRIs and I need a partial serotonin agonist to avoid the anxiety gap I'm experiencing. It also doesn't cause sexual dysfunction, it's pretty much the only SSRI that doesn't.
Try to uplift each other. I know I'm recovering. You might hit a hard point when your adrenergic receptors turn back on, you will be filled with fear and anxiety without the brakes of serotonin. But that means it's getting out of your brain. Buspirone is helping me with this anxiety, I just got it last night.

I know everyone has been traumatized by big pharma or whatever, but there is stuff that can help you guys out there. Talk to your doctors.
I'm outta here, I'll come back with updates and for any replies I should attend to. Dwelling here can really hurt you, I think, especially if you're mentally ill. Look up coping mechanisms for disassociation, y'all are disassociating on top of having your good chemicals blocked, and that makes you feel even more numb. I know this drug causes disassociation. I've felt cut off from myself before, I have depersonalization/derealization disorder, and this drug has caused the worst disassociation episodes of my life.

I've been going for walks, taking showers, and swimming around in my little pool in the back yard. Talking to my friends also helps. Being around people is good for disassociation too, have someone engage you.

I rejected help at first too. Please, seek help everyone. It's out there, I promise. I know it's hard but you need to try. The thing that has helped me the most is seeing what I can do to help myself recover. Peace out.
Click to expand...
Good luck to you thanks for the contributions and insights . Hope everything goes well for you
 
Rulomaner said:
So how do you think a protein can be healed from that damage, taking into account it can…?
Click to expand...
Microglia help replace broken synapses and receptors either themselves or by sending inflammatory messages to neurons, then neurons replace it themselves. But while invega is active in your system, microglias are also suppressed to some degree.
 
Baddream said:
Talk to your doctor
Click to expand...
High chance they won't know shit, they'll likely tell you to take more invega or antidepressants.

Many people here did ask and similar things happened.

Go talk with someone who works on producing organic/chemical compounds, who is good in neurochemistry or biochemistry.
 
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