Codeine and CWE Megathread - The long awaited!

[Sustanon]

That is surprising. I find my usual dose of 360, or up to 540 if I have been taking it more than a few days in a row, gives me a really good buzz for between 4 and six hours. Benzos improve it but don't extend it. Thought this was normal.

With a low tolerance it will last ages, I used to nod like crazy from 600mg for 4-5 hours but now days doesnt come any where close to it.

 

[Mr Blonde]

^ Amen to that.

 

[tyrael]

.....
Take a look at source 21, it's a study where they attempted to use fluoxetine (Prozac) to inhibit CYP2D6 and thus reduce the use of codeine by those addicted to it.
......
I used codeine for a while alongside fluoxetine a few years back, and the effects were significantly reduced. The same thing happens if I take promethazine before codeine, as promethazine is an inhibitor of CYP2D6 as well. It can make three boxes feel like two or less.
.....
This is just my personal experience and isn't a scientific study,
......

Total agree M_B. I've personally read (could dig them up if required) many studies regarding the use of (particularly) the CYP2D6 enzyme - although not actually the inhibition of this (and certain other related) enzyme but more the fact that both fluoxetine's (and analogues, commonly in Australia - paroxetine) and codeine's catabolic pathways intersect here. And are competitive substrates.

Subjectively, I've experienced quite a diminished effect of codeine. At a guess, the fluoxetine/paroxetine have a higher affinity to the enzyme receptors!

I do CWE's quite reguarly from panadeine extra.....

Again, agree with both Sus and M_B. Additionally however, I personally would advice not to use panadeine (paracetamol) to do your CWE. For a few reasons (I've posted multiple times here. If i get time I'll try to link it. Otherwise it's further up a few pages).

With a low tolerance it will last ages, I used to nod like crazy from 600mg for 4-5 hours but now days doesnt come any where close to it.

Take me back to those days Sus!! PLEASE?!


As an aside, hows ya studies going M_B?

 

[clear_sky]

SO I've just read this whole thread... and having trouble working out the math.

I'm about to embark on my first CWE extraction. I have a bunch of Panadeine Forte tabs - 30mg codeine+500mg APAP.
I don't have much of an opiate tolerance. I don't think. I've been taking 100mg-200mg tramadol for the last week or so, not every day.

Question 1 - How much codeine should I aim for to get a nice buzz?

(Follow up) Question 2 - (and this is probably really stupid but there are so many formulas in this thread that I'm just plain confused). For the amount of codeine that I'm supposedly aiming for - how much water do I use? I gather: not less than 50ml and not more than 150ml.
I'm good at math but chemistry was never my strong point (now I regret not paying attention at school!). So how do I work out this ratio of water to the amount of APAP? Does it depend on how much codeine I want to end up with?

 

[Mr Blonde]

^ I find tramadol and codeine to be very different substances, I never got a good effect out of tramadol personally. Most charts you can find will state that codeine and tramadol are around the same potency I believe, perhaps with tramadol being a bit more potent. However for reasons I won't go into, tramadol works through some different mechanisms.

I'd probably go for around 240mg for your CWE, you could take it up to 300mg probably if you are concerned about tolerance. Do you have an antihistamine on hand? That will help reduce the nausea and histamine reaction which are your main concerns of dosing too high.

(Follow up) Question 2 - (and this is probably really stupid but there are so many formulas in this thread that I'm just plain confused). For the amount of codeine that I'm supposedly aiming for - how much water do I use? I gather: not less than 50ml and not more than 150ml.
I'm good at math but chemistry was never my strong point (now I regret not paying attention at school!). So how do I work out this ratio of water to the amount of APAP? Does it depend on how much codeine I want to end up with?

50mL should be fine, you could even go a bit less as due to the fact you have Panadeine Forte you will be using less tablets.

When I do a CWE I am not exact with my measurement of water, I would just use enough that the tablets are dissolved... probably no more then 200mL but I was using a lot more tablets then you are.

So how do I work out this ratio of water to the amount of APAP? Does it depend on how much codeine I want to end up with?

It's more to do with how many tablets you have. Some people suggest 1-2mL per tablet.

 

[clear_sky]

I think I'll try for 240mg and see how I go from there. That's 8 tablets... I'll just go with the 50ml, like you suggested :D
I'm taking alprazolam so I shouldn't go crazy with my first time dose, seeing as I'm not exactly straight to begin with

I don't have antihistamines around the place BUT I do have some Maxolon.
I'm told it works wonders for nausea - I've never had it, it's left over from when I had to take meds a couple of years ago.

Also - this debate about cotton t shirt vs satin vs coffee filters?
Coffee filters are not an option, since I don't have any.
I have plenty of tshirts. But I also have this fabric that's not unlike satin, but without the satiny sheen.
As I understand it, I want to be using fabric with the tightest weave, so as not to let the APAP through?

 

[tyrael]

+1 for M_B's entire post, listen to that fella, he knows his shit.

Regarding taking alpraze and codeine, I would advice to not take them concurrently! At least for the first couple of times of dosing codeine!

Secondly - antihistamines - I'd suggest Phenergen (promethazine being the drug name). But this is generally personal choice. When I was dosing I would use it since it has the added benefit of being a mild sedative (for some).

Thirdly, I'd doubt at those doses you'll feel nausea! At least nothing a little lie down for 5mins wouldn't fix. If you do want to cover all bases and have an antiemetic at the ready - don't even bother with metoclopramide (Maxalon)! It's absolutely useless, for any suggested indications! -_- lol

And finally, on the topic of filtering, you basically want to filter as much unwanted product (in this case, paracetamol) as much as you're physically possible!

But tbh to what degree is up to you! Some people just filter through a shirt - just enough to remove the larger particles. Some people like to do that, multiple times, then filter through a coffee filter (multiple times?) and if you really want to be sure almost all of the paracetamol is removed, you could filter the solution again through micro filters!

If you're after advice, you'd be pretty safe if you're filtering through a cloth (to remove the large particles) and then a coffee filter once or twice! The remain paracetamol would be equal to, or less then, what one would consume taking them as per the directions.

 

[bobbydarren]

I do CWE's quite reguarly from panadeine extra and was wondering if anyone knows how to make the affects last a bit longer?? Each time I do it it feels really good but for only about fifteen to twenty minutes. Is there a way I can increase the potency or make the euphoria last longer??
thanks

I find compounding codeine works better than just taking codeine all at once.

So i take dxm, 45mins later take codeine, then soon after take prometh and dxm and 45mins later take codeine again, but a smaller dose. maybe 1/3 or 1/2 original dose.

The effect I get from final codeine dose feels stronger than original. So in this manner you get the extension of effects. But you should know. it's often said codeine won't work for many hours after initial dose. And also people have tried what I just outlined, and said it doesn't work for them.

 

[clear_sky]

Regarding taking alpraze and codeine, I would advice to not take them concurrently! At least for the first couple of times of dosing codeine!

Secondly - antihistamines - I'd suggest Phenergen (promethazine being the drug name). But this is generally personal choice. When I was dosing I would use it since it has the added benefit of being a mild sedative (for some).

Thirdly, I'd doubt at those doses you'll feel nausea! At least nothing a little lie down for 5mins wouldn't fix. If you do want to cover all bases and have an antiemetic at the ready - don't even bother with metoclopramide (Maxalon)! It's absolutely useless, for any suggested indications! -_- lol

And finally, on the topic of filtering, you basically want to filter as much unwanted product (in this case, paracetamol) as much as you're physically possible!

But tbh to what degree is up to you! Some people just filter through a shirt - just enough to remove the larger particles. Some people like to do that, multiple times, then filter through a coffee filter (multiple times?) and if you really want to be sure almost all of the paracetamol is removed, you could filter the solution again through micro filters!

If you're after advice, you'd be pretty safe if you're filtering through a cloth (to remove the large particles) and then a coffee filter once or twice! The remain paracetamol would be equal to, or less then, what one would consume taking them as per the directions.

Thank you for your bits of advice, muchly appreciated!

I had been dosing up on alps throughout the day and thought I might as well give it a shot. I think I've developed a high enough tolerance for it. Anyway, I enjoyed my CWE codeine experience The dose I had was probably around 260mg - I used 9 Panadeine Forte tabs and I estimate that I lost some codeine during filtration. I think it's a low dose (compared to what some of the other posters in this thread are having) but did absolute wonders for my sciatic and chronic back pain!

The process was very easy, can't thank enough everyone who posted here and explained the whats and hows. Special thanks goes, of course, to Mr B :D

I filtered three times through fabric with quite a tight weave (satin but not satin). I think it worked well, I forgot to wet the fabric the first time, then did another filtration with wet fabric, and a third one with the two wet pieces of fabric laid over each other. I ended up with more white gunky stuff each time. Surprisingly, the solution wasn't overwhelmingly bitter, I had it like a shot and chased down with some water. Not too bad at all, but then again I don't mind sublingual alps either. I'll get some coffee filters when I can, but I'll also try to find out what this fabric is called because I think it filters much better than cotton shirts.

I felt a little bit of nausea at some point (around half an hour after ingesting,), as well as chest tightness. It wasn't overwhelming, I ate some food and had a pretty chilled out couple of hours without any pain.

One strange side effect though - now I'm extremely awake even though it's the middle of the night and I had a long active day.

 

[Mr Blonde]

^ Yeah opioids can cause insomnia... if I were to take a sedating antihistamine with it though then it's usually not a problem. Glad to hear you had a safe, enjoyable experience.

The effect I get from final codeine dose feels stronger than original. So in this manner you get the extension of effects. But you should know. it's often said codeine won't work for many hours after initial dose. And also people have tried what I just outlined, and said it doesn't work for them.

I've tried this, and also tried it with an equal re-dose and did not experience anything but a prolonging of mild effects unfortunately.

Also, I find taking promethazine before codeine can reduce the experience quite a lot, most likely due to CYP2D6 inhibition. When I've made the mistake of taking the promethazine before hand, I get extremely annoyed at myself over it.

 

[drug_mentor]

Been smashing codeine daily for the better part of a week after a few months abstinence from opiates, I really did forget how much I love this drug. Usually if I use opiates I like to nod my tits off but there is just something about codeine that despite the feeling being rather mild I still feel very content. I notice like half the chemists I have hit lately haven't had 40 packs, but 50% or so have been willing to sell me 2 20 packs in the one transaction.

I had the oppurtunity to buy 'Mydol' 40 tablets the other day, which are 15mg codeine/500mg paracetamol which works out to my usual dose (600mg) in a single packet, however I found the cost to be around 150% of what I would usually pay to acquire 600mg with standard 10mg chemists own tablets, and due to financial constraints I opted not to purchase them. I remember a while ago using panadeine extra for a CWE and feeling as though it did work slightly better for the same dose than a weaker formulation would, could anybody with experience comment whether it is worth forking out the extra few dollars for the stronger 'Mydol' forumulation or is it no more potent than 600mg of chemists own?

 

[Nozphexezora]

If two different brands contain the same drugs(in this case paracetamol and codeine), then they're both the same- regardless of the price. However, the filling might be different and the general packaging may be different as well. I'd just go with the cheaper brands, that's what I do.

 

[Sonny Jim]

I remember a while ago using panadeine extra for a CWE and feeling as though it did work slightly better for the same dose than a weaker formulation would, could anybody with experience comment whether it is worth forking out the extra few dollars for the stronger 'Mydol' forumulation or is it no more potent than 600mg of chemists own?

A more concentrated codeine solution will hit harder for the same dosage.

This is especially true for opiates (and benzos) because they are absorbed relatively quickly.

The concentration of the codeine solution is directly proportional to the "rush".

So I would say that if you notice a difference it is worth it. The initial rush is such an important part of the experience.

 

[Nozphexezora]

A more concentrated codeine solution will hit harder for the same dosage.

This is especially true for opiates (and benzos) because they are absorbed relatively quickly.

The concentration of the codeine solution is directly proportional to the "rush".

So I would say that if you notice a difference it is worth it. The initial rush is such an important part of the experience.

Wow. I didn't know that. What if I were to fan-dry the filtered solution until there was only a few ml left?

 

[c0nzor]

I would add putting it in the freezer for 15-20 mins to let crystals of paracetamol form after filtration to ensure optimal purity for Mr. Blondes Extraction method. Well worth the wait for a healthy liver =)

 

[Sonny Jim]

Wow. I didn't know that. What if I were to fan-dry the filtered solution until there was only a few ml left?

well, you have to keep in mind that if you get it down to only a few ml it is going to be difficult to work with and even more difficult to get the whole dose down to your stomach/duodenum.

With oral opiates, I just follow the general rule that the more concentrated the solution the better. If people are only using 80-100ml to do a CWE then it is going to be relatively concentrated any way. This is a very important rule for PST/PPT, if you want a rush from it.

 

[Mr Blonde]

^ Kinda off-topic, but you get a rush from PST? I've had intense experiences with it, but it never came on with a rush.

 

[Nozphexezora]

What are high doses of PST like in comparison to heavier opiates like Oxycodone or Heroin? I've only ever taken PST and codeine because I'm a tightarse, but some people say that neither are anything like Heroin or Oxies.

 

[Mr Blonde]

^ I haven't used H, I've used oxycodone, morphine, fentanyl and OH-Me-fentanyl before. They are all more similar to codeine then to PST in my opinion/subjective experience. PST has more side effects, comes on slower but lasts longer then many other opioids. I find PST and poppy pod tea to be fairly sedating as well, more so then codeine and oxycodone.

I might be biased, but I am a huge fan of codeine personally and although it is somewhat weaker and has limits on how it can be used, the euphoria and experience it gives is similar to morphine and oxycodone though they have their differences and the fact they (and heroin) can be injected/smoked to provide a very intense rush means that codeine is often underrated, but those are just my thoughts. You can get get a lot higher on morphine or oxycodone then with codeine, but I've had some very good experiences with codeine as well.

 

[Sonny Jim]

^ Kinda off-topic, but you get a rush from PST? I've had intense experiences with it, but it never came on with a rush.

yes, when I prepare a very concentrated batch of PST the rush is sublime! It comes on about 15 minutes after consumption on an empty stomach. I am a long term user of opiates and have used opium (raw), pods, straw, seeds, heroin, morphine fentanyl oxy etc and I actually enjoy a properly prepared PST dose is a close second to eating raw opium. My tolerance is at 2-3kg of reasonably potent seeds but it varies a lot. I try to keep it at about 2kg and have done a pretty good job of it over the years.

I love the multi faceted nature of the raw opium high and yes, it comes with a lovely rush on an empty stomach. Of course it is a different rush to IV H but it's still great.