Yes. No it will not reduce dopaminergic effects at that dosage, but keep in mind that as part of its pharmacological profile, clonidine does reduce dopamine release indirectly. That is not a lot and should just take care of side effects or you might not even feel it at all and need to take more. Just stay safe. I would start with .1 or even .05 depending on your stimulant dose and clonidine tolerance.
which stimulant are you taking and what dosage? I would not recommend taking a beta blocker with either as it will tend to make blood pressure and tachycardia worse.
I thought they disproved that in a newer study and it was just a hypothesis before about unopposed^alpha agonists. It doesn't block; it activates. The alpha blockers work on the postsynaptic alpha 1 adrenergic receptors.
Clonidine and tizanidine work on the presynaptic alpha 2 receptors. Since they are autoreceptors, blocking them would actually release norepinephrine (think of it as a feedback loop - the autoreceptors exists to control norepinphrine release from the presynaptic neuron, so when they are activated, they shut down norepinphrine release, so in a sense, they are inhibitory). So alpha blockers (antagonists) at this site are stimulatory, ie they release norepinphrine, such as yohimbine and mirtazpine.
That’s great because im on a very hard stimulant binge….daynavel…ugh…o hate abusing stims let alone long acting as in 14 hours acting stims. Feels like im almost losing my mind at times.Absolutely. I always found Clonidine (Catapres) to be that little push over the edge if I'm feeling a little too wired/rattled and it's great for this purpose. You're not dealing with any seriously dangerous drugs here so you can experiment a little bit. I'd say, try taking 0.1mg Clonazepam with your stimulant to see if that makes the difference you're after. If not, I would first try 1.5 tablets before actually trying 2 tablets. This is a pharmaco;logical combination that is actually used just for this purpose, so nothing crazy here.
i took .5mg maybe I need to take more but guess idk why I didn’t. So 1mg should be safe? Wait the pills are .2mgnever done stimulants or taken clonidine, so I can’t speak from personal experience. However, as others have already said, clonidine is probably much safer than other Downers especially GABA drugs, like benzodiazepines or alcohol.
Actually, let me rephrase that. Clonidine is probably safer in that it doesn’t carry its own risk of psychological dependence, however, I’m sure it’s pretty potent and has strong cardiovascular effects. it also has some rather unpleasant side-effects like muscle weakness, Global pressure, fainting and paradoxical insomnia.
On the other hand, if I remember correctly, it has been used in the management of hypertension related to stimulant like recreational drugs.
Probably going inside the hospital tomorrow. Probably should ho tonight to so I can get checked out but I always feel out when I’m stimming for no reason.
Then again 28 pills of 14 hour long acting race mix amp idk….im used to d amp. And it’s nothing like this. D amp much better this shit is I’ll uncomfortable
WTH is fencamfamin? Well I just took .1 mg before I read your post go figure lol. But it’s not dangerous just not as effective right?Clonidine only acts at alpha2 adrenergic receptors so there's still the effect of beta receptors in the periphery that isn't being addressed. Propanolol may be a better drug to use but talk to a physician before implementing anything like that
Or just use fencamfamin and forget about cardiac side effects of the amphetamines
No. Not likely but it depends on the person. I’m just fucked up.I honestly don’t know much about clonidine dosing, but maybe you could take another two pills and wait an hour? I would definitely avoid using any more amphetamine, it will only make your situation worse. If you need to crash, just distract yourself with the fun activity or try to sleep. you’ll need to crash in the end, but the more you try to fight it the harder you will eventually come down.
I’ve never done psychostimulants myself which means I’m missing out on some potentially amazing drugs. However, it also means I’ve never experienced a stimulant binge and the associated crash so the things I’m saying, are what I’ve heard from other people.
I’ve always told myself that if I ever have the chance to try, amphetamine type stimulants, I would only ever take them orally and I will never re-dose on the same day. as you seem to be an experienced stimulant user, if I stick to my plan, is it easy to avoid getting into binge cycles. I know psychological dependence with any doses is possible, but let’s assume I only ever took between 10 and 20 mg of amphetamine in a given day orally. is it likely I will start having urges to take more or to start taking it via different routes?
Sorry for all the questions, I’m just extremely curious
I really want to drink a c4 energy drink but likely not a great idea. Sto it has l tyrosine and it will wake me the fuck up. I’m guessing it’s too risky tho co Sri g the amount I’m onI got a serious fucking problem with these stims. Good thing only one left.
But not so sure it’s safe to take more so why the hell did I…I guess with probability it’s probably safe but idk l amp I do t mess with normally. And this is racemic amp.
Idk it’s like it almost takes you there but them stops just before so it makes me want to dose more but that doesn’t work because it’s a slow released formulation. Idk my mind clouded