• N&PD Moderators: Skorpio | someguyontheinternet

can impacted stool "hold" and contain vast stores of active amphetamine (Adderall)?

Since this thread is basically about speed and shit I thought I'd share.

After being prescribed Adderall for years, and being used to taking a shit right as it kicked in.

I found I had some sort of "reverse placebo" effect where if I felt like i had to take a shit, I'd also feel speedy, despite the fact I hadn't taken a thing.
 
MacTavish I find your case intriguing. There is intimate and instant connection with the digestive tract to psycho-physiological happenings, which the mainstream western science is pretty much unaware of.

I for one get very real adrenal surges triggered by disrupted bowel activity. Usually they are just tachycardia, uncomfortably quick BP rise accompanied by minor visual impairment and heart arrhythmia in the initial stages of taking a shit. Sometimes though - outside the loo - it may be full-on adrenergic storm with all the strobes and whistles and altered mental state lasting hours.

The more severe cases have occurred in the weeks after mild single consumption of research stimulants, along with constipation and bowel problems that sync with the symptoms. I have theorized that either there are residues of long-lasting active metabolites in my gut, or the gut has been damaged so that conglomerated toxins enter my system whenever highly toxin-concentrated stool arrives at the damaged site (in the correct angle, I should add :D).

I fail to see anything psychotic in your theory. It is highly appreciated as it brings supporting insight to another one confronted with rare medical symptoms unexplainable through usual methods. It's astounding how narrow-minded and prejudicial the elitist folks can be when evaluating stuff coming from an amphetamine abuser (which you doubtlessly are if one needs to categorize, however which should not automatically invalidate pioneering insights). Maybe use a bit more jargon to comply with the proud ADD inhabitants' manners no? Thanks for sharing anyhow.
 
^I'm very glad to hear this. You sound like you know exactly what I'm talking about with the bowel movement and angle of feces in relation to the intestinal wall and how this impacted amp could "rush" into my bloodstream. I know I've said it in here many times but I truly think that amps got (and still ocassionaly do) get stuck in my stool. One thing I don't think I mentioned earlier was that I was also concurrently taking 3 different antacids (Tums, Omaprazole, and Sodium Bicarbonate - mainly for potentiating) I wonder if these antacids reduced the acid levels so low that the actual capsules did not dissolve fully. Since I'm a chronic abuse case my gut is kind of a mess and during this time the only thing I was eating for any length of time was adderall XR capsules.

As far as the psychosis, I don't think at the time I was explaining it here I was fully psychotic either. My reported observations were indeed what I believed might be happening at the time.

So do you take antacids at close to the same level I do? I can't think of any other medications I was taking at the time. The only other thing I was taking religiously at the time was my Lexapro daily 30mg and possibly some propranolol.

Do you still take amps and when you do, do you ever get these strange sparkling pins-needles pains shooting down nerves or some other type of biological conduit? I think these may be vasospasms but I can't say for sure. It actually feels like there are crunchy tiny little sharp pieces of broken glass getting pumped down nerves or veins of something. It hasn't happened to the high level it did in this episode again but I still on occassion when my bowels move I feel effects clearly hitting. And As I've said here many times as well I can't find any info on this. I have my eye on this situation though I don't want to replicate it for verification. Like I said I'm pretty sure I got hit with around 300mg's all at once.
 
In this thread: a guy who is going to have serious problems with hemorrhoids.
 
for one get very real adrenal surges triggered by disrupted bowel activity. Usually they are just tachycardia, uncomfortably quick BP rise accompanied by minor visual impairment and heart arrhythmia in the initial stages of taking a shit. Sometimes though - outside the loo - it may be full-on adrenergic storm with all the strobes and whistles and altered mental state lasting hours.

There could be a very simple answer to this, it actually has nothing to do with medications at all. It actually could be due to vagus nerve stimulation. The vagus nerve supplies the neck area, chest and intestines. The vagus nerve can be stimulated many ways...fear, pain, and HAVING A BOWEL MOVEMENT, "BEARING DOWN", OR URINATING. When it is stimulated, it causes bradycardia ( a lowering of the heart rate), cardiac arrythmias (irregular/erratic heart rythym), cool, clammy skin and can even cause fainting. In some (fairly rare) instances, the resulting arrythmias can actually be lethal, hence the unfortunate stories you may hear of people in the medical field oten find deceased pts on the throne. It is very true, especially in those pt's with a history of heart abnormalities to begin with. In that setting, it is more common than you would think, which is why people with certain cardiac histories are placed on a strict regimen of stool softeners and laxatives.

Interestingly enough, if any of you reading ever suffer from palpitations, one remedy (it WORKS cuz I've tried it) is to bear down (aka, also called the "Valsalva maneuver") as though you are having a BM...do this a few times, taking breaks in between with some deep breaths, and sure enough..your palps will resolve. Again, this is thanks to the vahus verve stimulation.

Eliphaz, it really sounds as though you may have experienced a vagal nerve stimulation in the past....which would explain the rebound tachycardia (that happens after the initial bradycardia), visual disturbances (could have been the precursor for fainting and you just somehow managed to not get quite that far) and the like. Something to consider anyway.

A pretty good article that explains what I'm talking about is here:
http://www.healthguidance.org/entry/12051/1/Vagal-Nerve-Fainting.html

Soap, while your theory is certainly interesting and thought provoking, I find it very unlikely. It just isn't feasible that the pill(s) remained intact during the ENTIRE digestion process (which is quite long and involved) to make it to a piece of hard impacted stool. I say that taking into consideration your "messed up" GI tract (which, have you have actual GI problems diagnosed, or are you sort of making an educated guess based on your symptoms?). The whole scenario is just too unlikely, IMO. Impossible? Probably not, but very unlikely.

It genuinely sounds as though you are simply WAY overdoing it on the amps, and you body is paying the price, with involuntary tremors (common in overboard amp abuse), and the other symptoms you mention. For you to be having seizue activity, there would almost definitely be other very tell tale signs and symptoms.

The very best advice I can give to you is to REALLY try to cut back on your usage, as you are really and truly entering some danergous territory here...and also, if these things continue, see your doctor and ask for a Neuro referral. Thing is, fo you to be properly worked up, you would have to be 100% honest about your amp usage,otherwise you might as well not even waste your (or the doc's) time.

Hope you're able to ease up for your health!!
 
^thanks good info. I was strictly guessing about my messed up bowels. There is probably no true disease affecting them...besides the disease of addition. Yeah I know i gotta clean up this tired old act. I can feel death closing in this time. Without question I'm in a bad way. See, I'm too good at living like a freak, it just comes naturally to me. Hallucinations and delusion are my friends that come out and play at recess, they are no longer scary to me. I'm sure that I am certifiably losing it but addiction has got me down bro. I'm trying to reign things in. I have another self-imposed hell to deal with.
 
happygoluckygal said:
Eliphaz, it really sounds as though you may have experienced a vagal nerve stimulation in the past....which would explain the rebound tachycardia (that happens after the initial bradycardia), visual disturbances (could have been the precursor for fainting and you just somehow managed to not get quite that far) and the like. Something to consider anyway.

Thanks for the reminder, I had considered defects of the vagal nerve earlier but had somehow discarded it as invalid theory. It's possible that the vagal nerve is involved, but I suspect there is more than that to the picture in my case. See, I may be standing somewhere peacefully when the bowel-connected heart flutters, blood pressure fluctuation etc. occur, I usually wonder like "what the fuck is wrong again, what did I eat for this to occur" (as eating something stimulatory or unsuitable for my sensitized system causes similar effects) after which I notice the gut activity and can then foresee the soon to arrive need to have a shit. The trigger definitely is not posture, neither is it any immediate psychological factor, but if bowel movement by itself can cause vagal nerve stimulation then that may well be the route through which the adrenal surge occurs.

However, the vagus nerve is just a relatively insignificant intermediary in the attempt to find the ultimate reason, and thus remedy for the nasty symptoms.

So do you take antacids at close to the same level I do?

Not likely close to the level you do, but I do take lansoprazole daily at the present and while easing my esophagitis symptoms I have no doubt it exacerbates the constipation and bowel difficulties. The simplest explanation would certainly be that the (up to 99 percent) reduction in stomach HCl that antacids & PPI's cause, would cause toxic / active constituents of ingested stuff pass incompletely digested to latter parts of the GI tract and be released to the bloodstream from damaged gut at a site and rate that the system is not comfortable with.

I also take propranolol regularly, so there could a connection in the constipation side of things, but I cannot imagine that alone to be a significant factor.

Seeing ordinary food such as capsicum, seeds or corn pass through the entire digestion process relatively unchanged in a normal person, I have no difficulties to believe that synthetic XR capsules would easily do likewise even in a slightly compromised digestive system.

Do you still take amps and when you do, do you ever get these strange sparkling pins-needles pains shooting down nerves

When I take my small dose of a stimulant drug once or twice a year, I feel super healthy if I'm able to avoid / tolerate the excess sympathetic nervous system activation while coming up. But give 1 to 2 weeks after a single night's use, strange shit starts to pop up. Pins / needles yes, not painful but up to the level where I can wake up at night with either shallow or very strong pulse, not feeling my fingers or entire hand (WITHOUT LAYING ON IT) at all (can smash it to the wall with the help of the other hand without feeling a thing on order to make blood circulate again).

That, and other shit such as visual strobes, BP fluctuation near hyper- or hypotensive crisis, hypnagogic hallucinations etc. are clearly caused vasoconstriction, which I happily have found to respond to a small amount of diazepam for instance.

or some other type of biological conduit?

Biological conduit would be a perfect name for the eerie symptoms that accompany those caused by vasoconstriction. This includes heart "humming" like electric current would constantly pass through it, spasms in the chest muscles or twitching of the abdominal area, not only muscles but at times just minor visual abdominal vibration and instead a feeling like the intestines inside are trembling. I might also get red rash on the neck and whole upper chest.

Impaired peristaltis throughout the whole digestive channel is a reoccurring symptom, I can at times have great difficulties swallowing food and on the other hand :D passing stool. I do not know whether that specifically is caused by direct damage at the digestive tract or neurotransmitter imbalance, but the tendency that borderline social phobia, paranoid ideation (controllable, happily) and such psychic symptoms correlate with the extent of gut problems, would suggest the latter.

I still on occassion when my bowels move I feel effects clearly hitting

Yes, I can testify that bowel movement can cause visible and massive effects in the autonomic nervous system. Whether that is through the vagal nerve or at least partially due to psychoactive substance stored in stool is interesting, but the direct culprit would in my opinion be semi-chronically unhealthy condition of the GI tract. When considering the connection of neuromodulation to the GI functionality, it gets rather tricky. Thus the ways to track down and fix these problems will of course be highly individual and challenging.
 
Soap...if u took the XRs whole in capsules w/ antacids w/o eating they can float in your stomach (sometimes 8+ hours) without breaking down competely.

i have delayed stomach emptying on Addy's. 100mg IR chewed and swallowed over 5hrs with sodium bicarb doesn't work. When sleep is imminent I smoke bud, eat, lie down just to be SLAMMED awake by 100mgs when my body starts digesting the food i ate!

Calcium and Magnesium antacids give me the shooting pins and needles pains w/ adderall.

An electrolyte imbalance (esp Na or K) can cause muscle pains and fasticulations worsened by dehydration and low blood sugar can cause the muscles to painfully build up lactic acid.
 
^thanks good info. I was strictly guessing about my messed up bowels. There is probably no true disease affecting them...besides the disease of addition. Yeah I know i gotta clean up this tired old act. I can feel death closing in this time. Without question I'm in a bad way. See, I'm too good at living like a freak, it just comes naturally to me. Hallucinations and delusion are my friends that come out and play at recess, they are no longer scary to me. I'm sure that I am certifiably losing it but addiction has got me down bro. I'm trying to reign things in. I have another self-imposed hell to deal with.

i have had this situation many times- shooting pains in my intestines (i thought it was my liver), psychotic episodes, feeling of impending doom, halucinations. just cut out the amphetamines and go to the doctor and get diagnosed with depression, use the diagnosis as an excuse to take time off from any commitments (work/school) you have and give your body a rest. in time you will come back to normality:)

good luck
 
Well, laymans terms, I guess the adderall scared the shit out of you, huh?
 
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