I love the 'fallout' series games whilst tripping. They are RPG isometric perspective games, or the first few in the series were. Featuring skillset customization, bloody violence thats presented in a hilariously humorous way, along with funny as shit jokes in the text part galore.
Also the X-com series: UFO-enemy unknown, terror from the deep, apocalypse.
Doom 3 was classic on dissociatives. Really fucked up though, having demons jumping out at you from dark corners trying to rip off your face, always desparate for ammo, always ready to whip out that 12-gauge and cut loose in the face of a fireball-belching hell-imp blowing hellspawn brain matter over the walls, or unleashing a burst of superheated plasma bolts from your full-automatic plasma rifle into the face of (not that they HAVE much else than a face) tortured lost souls, coming at you screaming, to bite at you, whilst they burn in their own hell-fire and shriek. (and thats BEFORE you unleash your plasma rifle burst into their ugly mug. Or head-shotting a grossly, morbidly obese, tentacle-faced pair of mancubi with a rocket-launcher with a satisfying meaty SBPLORRRSHKHGH aARRRRGLHHHGHNKKH! sort of noise as their heads explode in a bloody mess of hellfire.) Doom 3 is fucked up sober. tripping its REALLY fucked up.