I have a friend who has been getting what seem like mild seizures the last few times she's taken 5htp to deal with comedown... not sure how common that is, but its like brain blacking out and before she seriously cut down she nearly fainted a few times... I don't know what brand it was, but no drugs other than E have been involved... I'll find out what brand it was and if there were any other active ingredients, but be careful with your dose, and if you have such problems cut back, that has helped decrease the seizure symptoms.