I haven't tried this in combomation. I am on baclofen. 25 mgs 4x daily. when I am off it, I notice no diffence. I would rather be on soma for muscles spasms, but the pain dr insists on baclofen. Also on 800mg Neurntin 4 x daily. And a few other opiates oc 10mg and Norco 10 mg both 4 times daily. Like I said I don't see any diff when I am off baclofen. I notice when I am off neurontin as I have diabetic neuropathy. And the narcotics I notice a diff as I am ruptured l3 l4 l4 s1 in my lower lumbar along with osteoarthritis and severe degenerative disk disease. On some days when its feeling so so I will go strictly wtih 800 mg Ibupro-phen and sometimes it really does help! I like those days
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