You have to admit it's getting better, it's getting better all the time...
I have personally met several people who claim that they had suffered schizophrenia, schizoaffective bipolar, 'classic' bipolar, autistic spectrum disorders, to an alarming degree, which was not controllable via any available 'medications,' which miraculously attenuated after the ingestion of a single dose of DMT (varying between the light buzzy ones and the ballbreaking fuckton doses).
I didn't know them beforehand though so I'm in no position to speculate how things have actually worked out for them - I just know that DMT has been a broad-spectrum positive factor in finding a better balance, WHATEVER that may be!
I once facilitated an oral DMT trip (acacia bark, ~10g. syrian rue 3g) for a good female friend of mine... she had been going through about a year of depression and mood swings (it 'comes and goes' with it coming more often than going), and she had been rather terribly abused sexually and emotionally when she was growing up, would depersonalize and start cutting herself, etc... needless to say I was scared shitless that she would flip out on the stuff, and worse yet I _could_ have said "nah, burden of care, can't in good conscience give you the stuff" (especially because I couldn't BE present at the time!!!

), but was utterly compelled to give her the doses anyways. What the hell, it had been doing so much good for me at the time and it didn't cost me jack shit, I was somewhat of a fledgling emissary of the stuff at the time, so...
Instead she experienced a lasting positive effect from that one dose alone (and even more lasting positive stuff from journeys later on) where she basically seemed to become 'totally OK with everything,' stopped thoughtlooping, starting eating properly again, becoming more socially active in a more constructive way, more self-assured, self-directed... went out and started tackling life like a 300kg quarterback. I'm PROUDA her...
Several of the people I have met who have claimed that it helped incredibly their various 'mental conditions' I met because they came up to me and went, "You wanna try some DMT I extracted?" Some of these dudes are incredible, extracting from three different types of DMT source and making up smoking mixes with like 16 different amazing herbal substrates in them like oldschool shamans recipies.. and we smoke it and it's amazing and all that

and then they go, "Yeah, if it weren't for this stuff I'd be in a fucking institution by now..." :D