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Anti-anxiety drugs

as far as drugs or supplements. i really really like l-tryptophan. serotonin increasers really helped me with my anxiety, and l-tryptophan produces a calm relaxed feeling that is hard to beat even with drugs.

as far as drugs, moclobemide i really like for instilling confidence well being, and also eliminating anxiety. luckily it's cheap and available and isnt addictive, and has virtually no negative side effects. moclobemide is one of my favorite drugs. http://www.biopsychiatry.com/moclobsocphob.htm. moclobemide increases energy and confidence by raising norepinephrine, which gives the feeling of being able to handle the situation, and it increases serotonin which gives a sense of well being and calmness, as well as a small amount of dopamine (not enough to tweak, but enough to cause increased desire to do things or socialize)

if stimulants help, i'd recommend selegiline or daytrana (sustainable stimulants). increased dopamine has been shown to help a lot in social phobia (see biopsychiatry.com)

a combination of dopaminergics such as daytrana , and l-tryptophan (serotonin) has recently solved all of my mental problems (mostly stemming from anxiety) and has proven to be the best combination for my anxiety that i have ever tried. Benzos i will note did not work very well for me.

Buspar is another solution. Benzo users will shit all over it, but i found it to be fairly calming, and not as seriously debilitating (benzos make me too mentally slow).

also look at gabapentin. it's really really cheap and incredibly safe, has no side effects, and has known to be calming in a way that is somewhat related to benzos but without a major tendency for addiction or dependency.

If a combo of gabapentin and dopaminergics didnt help, i dont know what would.

Try some of these and get back to us (ask your doctor)
 
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id have to suggest several things
lyrica kills anxiety
neurontin can kill anxiety
benzos are gold standard
opiates work as well if not better than benzos
kava works AMAZINGLY better than you would imagine
suboxone really really helps my anxiety
kratom-of the bali variety try like a tablespoon. definatly
peace
 
actualy i am a benzo head and HAVE given buspar a fair chance
to me, its not like it does nothing. for me it makes anxiety WORSE. no joke this coming from someon who takes 6 mg kpin every day as well as suboxone and lyrica and neurontin and whatever else i can get my hands on
-oh wait i and everyoen else seem to have forgotten th VERY BEST oldd time solution for anxiety (this si the TRUE gold standard)-
-----some Nice Heady Indica cannabis. heavy indicas are REALLY good at alleviating enxiety.
now add in a couple fat tires or whatever your favorte brew is, and your set to go!
peace ")
 
as far as opiates go, if you're interested in somewhat extreme solutions,

tramadol is sustainable (because it's so easy to get a hold of), and at a constant dose (ie not abusive dose) acts like a mini ssri and an opiate at the same time.

Kappa antagonists have been shown to be unique in their antidepressive action. separate from standard opiates - kratom and suboxone, both kappa receptor antagonists, cause a more unique feeling of happiness and confidence than other opiates. If you've ever had a dysphoric reaction from salvia, these drugs cause the exact opposite effect.
 
Scorched Soul said:
Wow,

I have to say, i am slightly disheartened by these replies, it sounds like there isnt really anything out there that can help.

With regards to the mdma, i have to say, my anxiety is no worse than before i ever used the stuff, its exactly the same.

I just need something that lets me not be so self-conscious and feel so inhibited all the time, i feel so anxious and nervous around people, i just cant seem to relax.

what are all the herbs that are known to reduce anxiety? i know valerian root is one, what are some others?
Click to expand...

don't be too disheartened, just because some of us haven't been able to overcome social anxiety doesn't mean you won't be able to. how old are you? i know some people who went through very difficult periods of social anxiety and insecurity during their teen years but overcame it (without drugs) and now have normal social lives. in other words, your case may not be as bad as mine.

read this: http://en.wikipedia.org/wiki/Avoidant_personality_disorder and tell me if it sounds like you. i am a classic case of avoidant personality disorder. if you go down that list of symptoms, i have virtually every single one. for me it has been a life long thing and it's been so bad at times its hard to even talk about. for example, in high school i couldn't take the anxiety of sitting at a lunch table with other people so during lunch time (which was an excruciating 45 minutes) i used to sneak out to my car and just sit there so i could be alone. it's pathetic looking back on it. but i've done so many things just like that. hopefully you're not this bad.
 
...holy shit, you did that too?

*reads the wiki link*

interesting. ive been called anti-social before, and even been diagnosed with social anxiety, but ive never seen that list...
 
yeah. ive been called everything in the book
when all is said and done
clonazepam is the answer for round the clock anxiety and prevention of attacks
aprazolam is gold standard for killing an attack in its tracks.
and temazepam is a GREAT hypnotic, you can actualy feel it even though you are addicted to other benzos.
diazepam at high doses would be my other choice for hypnotic. the z drugs dont do fuck for me anymore. arranging the right schedule of benzos is essential in living an anxiety free life in those that TRULEY need meds to function
peace
 
buspar and tramadol is all you need ...,who ever said gabapentin is safe i disagree lots of side effects doctor told me he know's best..!
 
Benzo's

Alcohol

Sex

Legal/OTC/Herbal:
Kava (easily #1 in this category)
Valerian Root
Hops
Skullcap
Catnip
Chamomile

All in the above category are most potent in the form of tea. Combining any or all of them works even better.
 
re:

Hey guys,

Thanks for all the responses! I'll do some research on all the mentioned substances, and get back to you with thoughts/comments.
 
re:

Hey guys,

Well, I've done some research on the substances suggested, and I think that I've identified a few that I would be willing to take.

Kava and l-tryptophan, I think I will definitely look into, as they both seem relatively safe. Am I right in thinking that tryptophan is totally safe?

With regards to Kava, it seems that there is an issue with liver toxicity when the kava is taken from the leaves, and that only kava taken from the root of the plant is safe. Is it better to get kava root and make a tea, or are there pill or powder forms available of the safer root kava?

Moclobemide seems interesting, but I am a bit weary of the potential negative effects. Can someone give me some more information on this drug?

Daytrana seems interesting, but the information I have seen seems to suggest that it used to treat ADH (sp?), and that its effectiveness with regards to anxiety is limited....any comments?

Thanks again guys, look forward to your replies.

Think Im gonna order some valerian root, kava root and tryptophan. Any advice on which types to get? Not brand names or sources, but are there certain forms which are better than others? eg. capsules vs powder etc.

Thanks again.
 
re:

I have found a place which sells:

'an extract that has come from Vanuatuan Raga Kava root'

It says it is Kava Kava root, so this is the safe version right? They sell a bottle of 60 200mg caps. What is the normal dosage for this?


I have also found a place which sells l-trytophan, 90 500mg caps. They sell it plain, and also with Vit B6 and Niacin. Which one should I go for?


Can kava and tryptophan be combined? I am also going to buy valerian root. Can these all be taken at the same time? Should they be? If someone could advise on what dosing and combos would be effective, as well as safe, that would be great.

Thanks guys (and gals)
 
I would buy 5-HTP instead of L-Tryptophan. But that's only because I've used the former extensively and never the latter. 5-HTP doses are usually 50 or 100 mg at a time. I wouldn't buy a product that also contains B-6 and Niacin. I know that B-6 plays some role in the way that your body processes 5-HTP. I can't remember exactly what that role is, though. Nonetheless, I take 5-HTP (usually in doses of 50 mg x2 a day, but sometimes 100 mg) usually in conjunction with 500 mg of Vitamin C. That seems to be a pretty well-proven method.

I would NOT buy kava in the form of an extract. Look around. If you're using the internet, you can probably find really good stuff in a relatively short amount of time. Buy Kava root powder. Nothing else. It's the most effective. Fuck the capsules. I believe I remmeber peoplee saying that Hawaiin kava root powder is some of the better kava in the world.

Valerian root - buy the actual root. It looks like very small dark brown pellet shaped things. Almost like rabbit food. It smells bad, but it's very effective when you make valerian tea with the root substance that I'm talking about.

Another thing that you should definitely get that I forgot to mention is...

L-Theanine
It is an amino acid in green tea that produces relaxation and actually helps you to think more clearly at the same time (kind of like kava, only this provides better mental clarity). You can purchase L-Theanine on in its own in a capsulated form. It's the reason that the green tea doesn't make people jittery. The otherwise jittery-ness of caffeine in green tea is counteracted by the relaxing effects of the Theanine it contains.

I would buy all 4 of these suggestions if I were you.

- Kava root powder (look for a reputable source, Hawaiin kava is apparently some of the best)
- Valerian root (again, get the actual pieces of root and make tea with it. Don't buy it an encapsulated form)
- 5-HTP (just look for the best deal. I'd recommend buying a quantity of 50 mg capsules as opposed to 100 mg capsules, so you can better regulate your dosage)
- L-Theanine (usually sold by itself in powder-incapsulated form. usual dosage is 100 mg / pill)

Hope this helped!


Edit: I can give you tips and info on how and when to take these later. Combos, dosing, and what not... just not right now. But I will.
 
Nitrous,

Thanks for the advice. I have placed an order for the powder. With regards to the tryptophan, I am taking this because I have read that 5-htp leads to cardiac fibrosis, and that taking tryptophan avoids this. Can anyone else confirm this?
 
Scorched Soul said:
Nitrous,

Thanks for the advice. I have placed an order for the powder. With regards to the tryptophan, I am taking this because I have read that 5-htp leads to cardiac fibrosis, and that taking tryptophan avoids this. Can anyone else confirm this?
Click to expand...

yes. anything that increases peripheral serotonin is likely to lead to cardiac fibrosis. with regards to 5-htp, this can be related to a study on the green banana tribe, somewhere, where people were eating these bananas that contained a large amount of serotonin, and they had a really high incidence of cardiac fibrosis (findable on google).

all peripheral serotonin agonists cause cardiac fibrosis. it is a direct action of serotonin on the heart. (ergot alkaloids for example)

tryptophan is converted to serotonin only inside the brain, whereas 5-htp is converted to serotonin in the body itself

http://www.bluelight.ru/vb/showpost.php?p=5704433&postcount=7
 
forget KavaKava as powder. Only stuff that is gonna be beneficial is the fresh stuff, Fresh roots and leaves.

Or am i confusing that with Khat?
 
rave23 said:
forget KavaKava as powder. Only stuff that is gonna be beneficial is the fresh stuff, Fresh roots and leaves.

Or am i confusing that with Khat?
Click to expand...

there are varying opinions about this, but yeah the general consensus is that the kava at the grocery store sucks compared to the stuff you order online.
 
Newmoonrecord said:
yes. anything that increases peripheral serotonin is likely to lead to cardiac fibrosis. with regards to 5-htp, this can be related to a study on the green banana tribe, somewhere, where people were eating these bananas that contained a large amount of serotonin, and they had a really high incidence of cardiac fibrosis (findable on google).

all peripheral serotonin agonists cause cardiac fibrosis. it is a direct action of serotonin on the heart. (ergot alkaloids for example)

tryptophan is converted to serotonin only inside the brain, whereas 5-htp is converted to serotonin in the body itself

http://www.bluelight.ru/vb/showpost.php?p=5704433&postcount=7
Click to expand...

Shit. Thanks.
 
kava is best if its powder and fresh from a plant with very old roots.
liver damage reports mean nothing, they were VERY questionable studies, and they were all about an alcohol extraction of kava which iv read also extracts out certain kavalactones that PROTECT the liver.
natives have used kava daily in large doses for centuries and they have no reports of liver problems.
the best natural kava is kava king powder. very strong.
the best extract is a cold water extract, called Kaviar, and its soo strong that i cant take over one teaspoon of it (not joking) cause it fucks me up too much if i take more than that.
id also highly suggest cannabis of all kinds for the use of anxiety. for centuries, weed HAS been and i believe always will be, the GOLD STANDARD for anxiety. take a puff and chill homie
peace :)
 
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