I have been prescribed Concerta (27mg), which is a time-released form of methylphenidate (aka Ritalin). It basically provides approx. 6mg of MPH throughout a 12-hour period.
Around the 10-12 hour mark, I obviously get tired. This, I presume, is the result of neurotransmitter levels (principally dopamine and norepinephrine) going down.
Does anyone know how long after the comedown I should expect neurotransmitter levels to return to normal (more or less)?
Or rather, when should I expect MPH to stop inhibiting reuptake of (i.e., increasing) these neurotransmitters?
These are simple enough questions. If anyone wants to know why I'm asking, it's because I intend to take a substance that decreases norepinephrine levels (which is somethign MPH increases by reuptake inhibition). So I just want to get an idea if there would be an interaction where there might be long-term implications to consider.
Around the 10-12 hour mark, I obviously get tired. This, I presume, is the result of neurotransmitter levels (principally dopamine and norepinephrine) going down.
Does anyone know how long after the comedown I should expect neurotransmitter levels to return to normal (more or less)?
Or rather, when should I expect MPH to stop inhibiting reuptake of (i.e., increasing) these neurotransmitters?
These are simple enough questions. If anyone wants to know why I'm asking, it's because I intend to take a substance that decreases norepinephrine levels (which is somethign MPH increases by reuptake inhibition). So I just want to get an idea if there would be an interaction where there might be long-term implications to consider.
