• Psychedelic Drugs Welcome Guest
    View threads about
    Posting RulesBluelight Rules
    PD's Best Threads Index
    Social ThreadSupport Bluelight
    Psychedelic Beginner's FAQ
  • PD Moderators: Esperighanto | JackARoe | Cheshire_Kat

Adverse reactions to Rue as an MAOI

naura

Bluelighter
Joined
Dec 22, 2009
Messages
54
Location
Home is where your friends are
I took a capsule of harmala extracted from syrian rue to potentiate (MAOI) a 25mg 4-AcO-DMT trip [4-AcO-ahuasca]. the resulting trip was fabulous, and I had a positive time overall.

HOWEVER, while coming down off the combo, I had a scary episode that I think was related to the harmala. An absurdly violent thought/impulse entered my mind and was gone just as soon. To be specific, my girlfriend patted me tenderly, and i felt a brief flash of "i want to fuck your face up so it is an unrecognizable bloody pulp", which then dissipated. obviously I didn't act on this thought, because it's not even really 'of me' - i recognized it as being similar to effects caused by certain MAOI anti-depressants. In these cases, people have sudden violent thoughts/ideations often leading to self-harm or harm to others.

I've never had this kind of a response to an MAOI, and I've used harmala from rue many times. I think a complicating factor may be the fact that I was also coming down off ketamine at the time. K and MAOIs+trypts are not contraindicated, but their comedown together produced a bizarre response in me.

Has anyone ever experienced effects similar to the side-effects of some anti-depressants, as I did, off harmala (or any other MAOI used to potentiate a tryp)?
 
yes. the few times i have used harmala to potentiate ps. cyanescens shrooms, have ended in incredibly vivid OOBE/bad trip loops including "evil thoughts" and some ridiculous self-realizations that seemed to make sense at the time but in retrospect were absolutely psychotic.

it is because of these experiences that i would strongly caution anyone who thinks this is a good idea to RECONSIDER. any kind of rue-huasca combination has the potential to not only shatter your ego, but insert some VERY DARK thoughts into your mind, thoughts that you will know are evil, yet somehow cannot make them go away.
 
I never had anything exactly like that but rue in combination with mushrooms have certainly given me the impression that I was left completely vulnerable to thoughts of my own and effects or the action of the mushroom alkaloids.

It pretty much agrees with the theory, MAO which is your safeguarding system is inhibited allowing rogue shit to enter and sustain in your brain, endogenous or exogenous. I would always be careful with MAOI, period. And especially combinations, with less known compounds / research chemicals in particular.
 
I had a HORRIBLE reaction to Syrian rue once. I was testing out ground Syrian rue seed before I used it as an MAOI to potentiate DPT/DMT. I took just 1000mg of ground seed, not an extract, and I ended up getting intense dysphoria and flu-like symptoms and passing out for 18 hours. The normal dose for potentiating tryptamines is like 3000mg or more of seeds. I don't think I'll go near it again. In the future I'll be using pure tetrahydroharmine.
 
That definitely sounds fucked up!
TTH seems to be the best of the major harmala alkaloid principles doesn't it? (tetrahydroharmine, harmine, harmaline, harmalol, ...)

I was working on an extract at my fathers place this last weekend but I stopped when my vacuum filtration apparel did not appear to function properly. Now it's left to settle some floating cloudiness in the fridge. It's not that much material but I want to see if I can get a nice looking product and even separate harmine and harmaline.

For actual use I might look into ordering some pure harmine or TTH...
Really sucks that ayahuasca / oral DMT involves these MAOIs and that moclobemide is not cheap. I'd rather not go near any MAOI whatsoever. OK maybe deprenyl once or twice...
 
Personally I would REALLY careful when mixing MAOIs with ANYTHING not traditionally used... they open pathways which I feel could be damaging to the brain or body.
 
In the future I'll be using pure tetrahydroharmine.

Seems like somebody told y'all THH was better a few weeks ago and y'all gave them shit for it....

Who was that?

O ya.... ME!
 
I don't think I know what you're talking about, unless when you say "y'all" you're referring to everyone but the person you quoted.
 
i know i wasn't the first to suggest it

but when i suggested it here y'all said i was crazy or didnt know what i was talking about or atleast somebody did... something along those lines.
 
Top