nichtwahrMD420
Greenlighter
I have been on amphetamines' for ADHD for 9 years, and recently separated my shoulder about 3 weeks ago. I was recommended by an Arzt (physician) friend of mine to just take some oxy that was going to give me. I did so, but I've never had any relief, and or pleasure from oxy (doses of up to 120 mg IR). So I told him I wanted tapentadol, a new medication for various types of pain.
A little background on tapentadol-It is somewhat related to tramadol; but has a MUCH Greater pronounced Mu Opioid receptor binding and activating effect, which greatly increases it's analgesic effect, and it's euphoria. It is also coupled with a secondary mechanism of of norepinephrine reuptake inhibition.
With 100 mg of Nucynta combined with just 40 mg of IR Adderall, taken orally, for me was comparable, if not superior to the complete body orgasm and intense euphoria you receive from the first 250 mg of 90-95% Pure "white lady" that you insulfate as one line!!!!!
After taking my Adderall & Nucynta, I was getting ready for a day of reading and working on a reasearch project for my "Un-named Pharmaceutical Company Employer"; when after about 30 minutes, I had to stop the reading, and lay down on the couch because of the INTENSE ORGASMIC EUPHORIA that I was unsuspectedly suddenly experiencing!!! I had researched tapentadol rigorously before being prescribed it, and there was no studies or info on interactions, co-commitant use with stimulants, etc, except for the usual risk of serotonin syndrome combined with SSRI's or SNRI's, and risk of seizures.
I had assumed that it would feel somewhat like tramadol, and feel somewhat the same when combined with amphetamines, which is a nice "light euphoria" but nothing great. Nucynta and the amphetamines, however, was a VERY NICE SURPRISE!!!! To explain the experience in my head, it felt like I was flying through space at warp speed, that there wasn't ANYTHING in the world that could be painful emotionally or that there ever was any other feeling than this MASSIVE EUPHORIA I was experiencing!!!!
The "Non-Central Nervous System" effects were just as equally AMAZING!!!! My arms and legs were weightless, and touching them, and touching any object increased the euphoria!! It felt mentally, and physically as if I was in the middle of the best orgasm in my life, yet it felt in a sense 100 times as strong as that sexual pleasure
These effects, for me, lasted for about 4 to 6 hours, and the come down was nice and easy, as compared to the usual amphetamine crash, and opioid wear-off crap feeling. I repeated the same dose that evening to see if I would achieve the same effects, or was it going to be just like the cocaine tachyphylaxis, that you barely feel any euphoria & only reduce the major depression after the crash. NOPE, I achieved the same EUPHORIA as I did with the first dose of the combo!!! Simply AMAZING!!!!
I know some may cite risks of serotonin syndrome with this combo, or seizures; which may be true in certain individuals. But I felt no jitters, tremors, nausea, hyperthermia, etc, that are some of the sx/sx of serotonin syndrome.
The risk is fairly low with the dosage that was consumed, and as well, tapentadol, just as tramadol, isn't a very effective reuptake inhibitor of 5-HT (serotonin), and the mechanism is significantly specific to the presynaptic norepinephrine neuron; therefore if the dose isn't too excessive of either drug, in my opinion the risk is remote-if almost non-existant, regarless of the dopamine, norepinephrine, serotonin releasing mechanism from presynaptic neurons caused by amphetamines, as well as the reuptake inhibition.
Just as a trip report, I have to say I was SIMPLY BLOWN AWAY with the ORGASMIC EUPHORIA that I experienced. If anyone else has experienced what I have experienced with this combo, or if it was a bad experience, I would love to hear about it!!
Hope everyone has a safe and "responsible weekend"
-nichtwahrMD420
A little background on tapentadol-It is somewhat related to tramadol; but has a MUCH Greater pronounced Mu Opioid receptor binding and activating effect, which greatly increases it's analgesic effect, and it's euphoria. It is also coupled with a secondary mechanism of of norepinephrine reuptake inhibition.
With 100 mg of Nucynta combined with just 40 mg of IR Adderall, taken orally, for me was comparable, if not superior to the complete body orgasm and intense euphoria you receive from the first 250 mg of 90-95% Pure "white lady" that you insulfate as one line!!!!!
After taking my Adderall & Nucynta, I was getting ready for a day of reading and working on a reasearch project for my "Un-named Pharmaceutical Company Employer"; when after about 30 minutes, I had to stop the reading, and lay down on the couch because of the INTENSE ORGASMIC EUPHORIA that I was unsuspectedly suddenly experiencing!!! I had researched tapentadol rigorously before being prescribed it, and there was no studies or info on interactions, co-commitant use with stimulants, etc, except for the usual risk of serotonin syndrome combined with SSRI's or SNRI's, and risk of seizures.
I had assumed that it would feel somewhat like tramadol, and feel somewhat the same when combined with amphetamines, which is a nice "light euphoria" but nothing great. Nucynta and the amphetamines, however, was a VERY NICE SURPRISE!!!! To explain the experience in my head, it felt like I was flying through space at warp speed, that there wasn't ANYTHING in the world that could be painful emotionally or that there ever was any other feeling than this MASSIVE EUPHORIA I was experiencing!!!!
The "Non-Central Nervous System" effects were just as equally AMAZING!!!! My arms and legs were weightless, and touching them, and touching any object increased the euphoria!! It felt mentally, and physically as if I was in the middle of the best orgasm in my life, yet it felt in a sense 100 times as strong as that sexual pleasure
These effects, for me, lasted for about 4 to 6 hours, and the come down was nice and easy, as compared to the usual amphetamine crash, and opioid wear-off crap feeling. I repeated the same dose that evening to see if I would achieve the same effects, or was it going to be just like the cocaine tachyphylaxis, that you barely feel any euphoria & only reduce the major depression after the crash. NOPE, I achieved the same EUPHORIA as I did with the first dose of the combo!!! Simply AMAZING!!!!
I know some may cite risks of serotonin syndrome with this combo, or seizures; which may be true in certain individuals. But I felt no jitters, tremors, nausea, hyperthermia, etc, that are some of the sx/sx of serotonin syndrome.
The risk is fairly low with the dosage that was consumed, and as well, tapentadol, just as tramadol, isn't a very effective reuptake inhibitor of 5-HT (serotonin), and the mechanism is significantly specific to the presynaptic norepinephrine neuron; therefore if the dose isn't too excessive of either drug, in my opinion the risk is remote-if almost non-existant, regarless of the dopamine, norepinephrine, serotonin releasing mechanism from presynaptic neurons caused by amphetamines, as well as the reuptake inhibition.
Just as a trip report, I have to say I was SIMPLY BLOWN AWAY with the ORGASMIC EUPHORIA that I experienced. If anyone else has experienced what I have experienced with this combo, or if it was a bad experience, I would love to hear about it!!
Hope everyone has a safe and "responsible weekend"
-nichtwahrMD420
