6,7-Methylenedioxy-2-aminotetralin [MDAT]

[dread]

dmmda is active mostly as a 5ht2a agonist, conversion of the amphetamine side chain into a constrained indan would abolish all activity the same applies to almost all 5ht2a agonist phenthylamines.

Yes, but the inactivity wouldn't be due to polarity. And it might still have some monoamine reuptake inhibition properties...

 

[/navarone/]

Why? DMMDA is supposedly active... this would be less polar due to the alkyl groups on the amine.

Yah but 6,7-Methylenedioxy-8-Methoxy-2-dipropylamineindan-1-one would be a better anologue in my instincts.

 

[dread]

Yah but 6,7-Methylenedioxy-8-Methoxy-2-dipropylamineindan-1-one would be a better anologue in my instincts.

Why?

 

[/navarone/]

Why?

1) hydroxyl groups don't really get along with the BBB and like many other amphetamine analogues, the methoxy analogue is far more potent than the hydroxy analogue

2) It seems that the 8th indane conjugation is more psychologically effective than the 5th indane conjugation. In fact I think that bupropion would have higher stimulatoryb effects if the chlorine was placed at the ortho position.

3) The keto group at the beta indane position might give it higher adrenergic affects increasing its stimulating properties, although the chances of it being converted into a hydroxy might be just as likely as in Cathinone so maybe a methoxy group would be the best choice.

One way or another I would still propose my previous indanes as potential TRIs even if i have no SAR reference to support my ideas.

 

[/navarone/]

Also para-halo-7-methoxy-2-benzylpiperidine intrigues me somehow.

 

[fastandbulbous]

^ There's no 7 position in that molecule (piperidine is a 6 member heterocycle) and thw 2-para-halobenzyl indicates the naming is based on the piperidine ring...

Besides, 2-benzylpiperidine is just a reuptake inhibitor (not a very potent onr at that considering it's the basic structure of desoxy etc) with piss poor activity

Aromatic amine alert. Woluldn't let the stuff anywhere near me

 

[dread]

It seems that the 8th indane conjugation is more psychologically effective than the 5th indane conjugation.

They are one and the same, you know... indane is a symmetrical molecule.

 

[/navarone/]

^ There's no 7 position in that molecule (piperidine is a 6 member heterocycle) and thw 2-para-halobenzyl indicates the naming is based on the piperidine ring...

Besides, 2-benzylpiperidine is just a reuptake inhibitor (not a very potent onr at that considering it's the basic structure of desoxy etc) with piss poor activity

Aromatic amine alert. Woluldn't let the stuff anywhere near me

Woopsie, little mistake there, my bad.

@ Dread, yes they are symmetrical unless you conjugate them with something that neglects the symmetry, like the halogen I positioned on the phenyl.

What I would be interest about wold be a SAR report on the various amine variants (dimethylamine, dipropylamine, azetidine, and pyrrole) any suggestions?

 

[sefrutini]

Experience Report

Received some MDAT (Hex.Tc.1)
Bag is unlabelled but this is the only chem have recently bought, and the included disclaimer form says its from the expected site.

Looks exactly like this:
http://www.bluelight.ru/vb/showpost.php?p=8366358&postcount=208


80kg
Male
20 yrs
Good physical fitness from weight training ~3 times a week

I have taken 4MMC and MDAI before (that is all i have to compare it to).
With MDAI i noticed zero change from baseline at 500mg over 2-3 hours, although i did have a sample from the "dogshit brown" batch.

Took 30mg ephedrine and 200mg Modafinil at T -5h

T -2h
1 quite large granule on tongue (~5mg)
tongue goes a little numb, no other effects

T +0
20mg sublingually
held for 2 minutes before i'd had enough of the acidy salty plasticy taste and washed it down with water.
On and under my tongue is numb.
Nothing else to report

T +45
50mg dissolved in OJ. Only changed the taste a little.
Still Baseline.

T +1h
I evacuate a food baby

T +1h05
Still nothing, maybe a little shakey and alert, seems like anticipation though.

T +1h30
Its a very hot day today anyway, but i feel particularly toasty right now so i setup a large desk fan.
Other than that, negligible difference.

T +1h35
Catch up on the gossip from the 6-apdb and 5-iai threads

T +2h
25mg nasally
Burns to high heaven, most painful thing that has ever happened in my nose
150mg orally

T +2h30
I planned on (and tried) revising Quantum mechanics but was very easily distracted and subsequently joined my housemates who were having a nice cup of tea outside in the sun.
I feel a little uplifted, nose still hurts and is running.
A strange and subtle feeling as if there is "pressure" in my head, although it causes no discomfort.

T +3h
Still have the pleasant uplifted feeling, but its not very noticable. Its as if i have taken a mild antidepressant.

T +3h30
Not much change, I'm going back to my Quantum revision...
I would rate the effects as a 1.5 or 2 out of 10 in strength, and 6/10 for "niceness" lol.
If it were more potent then it would be a lovely chemical to relax with, but fair to say, i would have probably gotten this same feeling if simply someone were to deliver me some good news, or if i found a tenner on the floor....

T +5h
Again, not much change, effects might be dying away, but i'm not really sure.

All in all i'm glad i tried it, but definitely wont be dropping any more dolla just for a slightly elavated sense of wellbeing!!

[edit]
Just reread torturedrainbow's thoughts where he says 100mg hex.tc.1 was a good mdma sub.
I definitely disagree. Although i havn't tried mdma, one would hope its effects are 100x more pronounced than this was.
This has made me reconsider the validity of his other reports too.

@torturedrainbow, sorry dude its nothing personal.

 

[Madaboutmeph]

Thanks for the report.

How would you say it compared to MDAi? These seem to be the only two chems about at the moment apart from NRG and DMC and I can't be bothered with either of them again.

 

[sefrutini]

I found it better than MDAI, but then again, the MDAI i had did nothing for me even at a 500mg dose. Neither are worth it imo.

 

[Madaboutmeph]

ok thanks for the heads up.

 

[markyparky1971]

Hi. Newbie Here. Getting a delivery of this tomorrow am. will post a trip report within the next few days. Not holding out much expectation though from my reading research thus far, but we'll see. Kinda hope that I don't find it wonderful though, cos it seems to me from reading other threads that any newbie that gives a glowing report is automatically accused of being a vendor in disguise, and frankly, I have no defence against that. However, if it's shite in my opinion I'll say so. It does occur to me though that any reasonably intelligent vendor in disguise would post some shite reports on stuff like this to gain a reputation before givin a glowin report on something else they wish to peddle. Who to believe? At the end of the day my own experience ultimately. I'll share it and what others do with it or choose to believe is up to them.

 

[coffee23]

Hi. Newbie Here. Getting a delivery of this tomorrow am. will post a trip report within the next few days. Not holding out much expectation though from my reading research thus far, but we'll see. Kinda hope that I don't find it wonderful though, cos it seems to me from reading other threads that any newbie that gives a glowing report is automatically accused of being a vendor in disguise, and frankly, I have no defence against that. However, if it's shite in my opinion I'll say so. It does occur to me though that any reasonably intelligent vendor in disguise would post some shite reports on stuff like this to gain a reputation before givin a glowin report on something else they wish to peddle. Who to believe? At the end of the day my own experience ultimately. I'll share it and what others do with it or choose to believe is up to them.

Hi,

Looking forward to the report, thx.

 

[greenmeanies]

according to the nichols paper where he tested MDAI and MDAT compared to MDMA in trained rats, MDAT was much less potent than MDAI in substituting for MDMA.

no idea why vendors are trying to sell this one after the poor response that MDAI got.

 

[hx_]

according to the nichols paper where he tested MDAI and MDAT compared to MDMA in trained rats, MDAT was much less potent than MDAI in substituting for MDMA.

no idea why vendors are trying to sell this one after the poor response that MDAI got.

Probably as they can get nice shiny crystals of it rather than poo-brown powder!

 

[Flephedom]

when i bought MDAT recently I received brown sticky crystals, although when dissolved in water the brown colouring disappears and colourless crystals are left? i fear i have been victim of a scam..

 

[Torabora]

this is strange but maybe MDAT is not very good soluable in water but the brwon impurity is?
On the other hand its a Amine and propaply the HCl salt so it should dissolve in water....*head scratch* no idea what you got there ^^

 

[Flephedom]

ahhaa, the crystals did dissolve, they just took some stirring and some shaking.
didn't take longer than a minute and they were fairly big crystals.

i'ma go big on a dose saturday, i'll fill you in on the affects

 

[fastandbulbous]

according to the nichols paper where he tested MDAI and MDAT compared to MDMA in trained rats, MDAT was much less potent than MDAI in substituting for MDMA.

no idea why vendors are trying to sell this one after the poor response that MDAI got.

Stupidity & greed. I still have big doubts over the safety of MDAT