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Phenethylamines [2C-E Subthread] 2C-E Dosage and Methods of Administration

hippyflippy said:
my friend is getting some of this stuff soon... ive tried all the classic psychadelics, including cactus tea, but not really delved into the research chemicals... how is 2C-E and would it be safe to take a large dose if i find my self fairly comfortable with tripping, etc.?
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You should try a tiny dose (about 1-3mg) first, just to see if you have any bad reactions to the chemical.

If that turns out fine, then I'd recommend you go with a moderate to high/moderate dose for your first time, since you seem to know generally what to expect.

Also consider a sober (or at least "non-tripping") babysitter.
 
Has anyone tried a lower doses of 2c-e? I've taken it all the way up to 40mg, which I won't do again. However, about a month ago I took 8mg for an aesthetic enhancement kind of thing and the effect was more than I expected. I hadn't used any 2c-e in awhile and tolerance was not a factor. Strong stuff.
 
Depends on what you consider a 'large dose.' My first go with 2C-E was 16mg, and that trip was equal in every way to a good 250ug dose of LSD. It was far more than I would recommend to anyone new to the experience...but would probably be ok for someone experience.

Be aware that every 2mg can DOUBLE the intensity. My next trip with 2C-E was with 18mg, and it was twice as intense as 16mg. The next was with 20mg of 2C-E...and that dose went of the charts and blew away all but one previous LSD experiences.

Personally I think I was big-headed at the time....and 10-12mg is much more reasonable for a person's first go with the chem.

hippyflippy said:
my friend is getting some of this stuff soon... ive tried all the classic psychadelics, including cactus tea, but not really delved into the research chemicals... how is 2C-E and would it be safe to take a large dose if i find my self fairly comfortable with tripping, etc.?
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If you've never done it why start with a higher dose? You can always do it again in a week if you feel like you want more.

{Edited at some one's suggestion}. While no one here is suggesting that you start with 40 mg, I maintain my assertion that 40mg of 2C-E for most if not everyone is an absurdly high dose. If you want balls to the wall high dose psychedelic experiences do your body a favor and stick to a compound with a well established safety profile such as LSD.

Try no more than 8-12 mg at most for a starting dose. 2C-E has a definite physical load and it can be a little disorienting.
 
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whats the best way to mesure it out without a MG digital scale? just chop it into ecual piles? (assuming that what you get is mesured out right) or is the water idea better? i dont have the cash for a really nice digital :(
 
Never assume the weight you got is correct. You can buy scales that weigh to +/- 10 mg dirt cheap on ebay, and that is good enough if you use a dilution method.

Get a small brown bottle with a teflon lined cap, some distilled water, and a graduated pipette - all available at a drugstore (you can find a better assortment of small bottles and vials at the Container Store if you have those).

Weigh out say 100 +/- 10mg transfer it to the bottle, add say 20 mL of water using the pipette to measure it. This is not all that accurate but it gets you in the neighborhood. Make sure everything is dissolved, then you pipette out doses - 1 mL ~ 5mg. Once you are done, put the bottle on a level counter top let it stand for a minute and then use a fine Sharpie to mark the level of the liquid. Put a piece of Scotch tape over the mark so it can't rub off and put the bottle in the fridge. That way the next time you can look at the mark and know if a bunch of the water evaporated (it should not if you capped it tightly but best to mark it anyway).

This hardly quantitative chemistry, but then again, you are already at the mercy of batch to batch purity on all this stuff anyway. It's good enough for the job at hand, and a definitely lot better than assuming the package weight you got is accurate and cutting piles.
 
Need Answer About 2C-E

I'd like to first say to the moderators:

Would you please not close my post or redirect it to the 2C-E thread. I've read both of the threads, plus erowid, and nothing of them have answered my question. If you do decide to move this question, will you please wait until after I've had a solid answer?



With that being said, I just wanna know, will 5mg of 2C-E make me trip when taken orally? I know it won't be a really hard trip but I'm just trying to get the basic feel of the drug, because I hear it's quite intense and it's not a recreational drug, but I still want my visuals, just not anything overly intense..would this be recommended?
 
Probably a smart idea. Taking 1-2mg to make sure you don't have any adverse reaction of that your 2C-E is not contaminated with a DOx is also a good practice. You can read some interesting reports of low dose 2C-E in the book Thanatos to Eros by Myron Stolaroff which is online here:
 
yeah... so 5mg isn't going to make you 'trip' it will make you barely feel it. 2ce, while powerful at high doses, is a VERY recreational drug. your gonna need atleast 10 mgs to even see a slight movement of objects. id say 13-14mgs is about the equivalent to a 80mic acid trip. but its a very fun drug IMO.
 
You will probably be safe and more closer to the level you want to be if you take 10mg, but as others have already said, make sure you test the waters first with a lowish dose (1-2mg) to test against idiosyncratic reactions and to make sure you don't have a tenfold more potent substance (such as a DOx). You should do the test at least a couple of days before your main trip, don't expect any effects from the test run (other than treshold maybe). If you have no strange reactions, jump in at 10mg and slowly titrate up to the desired level from there (with at least one week between each trip, and 2mg increments - make sure to note that each 2mg increment is believed to double the response from 2C-E, so be careful with upping your dose). Best of luck, and please report back how it goes.
 
cornollio said:
yeah... so 5mg isn't going to make you 'trip' it will make you barely feel it. 2ce, while powerful at high doses, is a VERY recreational drug. your gonna need atleast 10 mgs to even see a slight movement of objects. id say 13-14mgs is about the equivalent to a 80mic acid trip. but its a very fun drug IMO.
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I've seen a friend have a fully fledged freak-out of really nasty proportions from just 10mg of 2C-E (& he's not a small bloke either), so go very carefully and titrate the dose for yourself. By all means take the dosage range suggested as a guide, but start really low and as oithers have mentioned, do a test run with 2-3mg to check for ideosyncratic reations to it first.

This is one drug that like LSD is not very forgiving psychologically if you jump straight in at the deep end without any precautions
 
Just a quick note to say that 2C-E does work very well rectally, however one must be very careful with dosage -- the already steep dose-response curve is made even steeper. I would not recommend doing any more than 15mg and you can expect effects close to 25-30mg oral. It also comes on very quickly (last time I was getting visual distortions within 2-3 minutes). I always give myself an enema before rectally administering drugs, so that might quicken the onset.

Also, if you are using it rectally as a way to reduce the nausea, this unfortunately does not work. 2C-E nausea is from the brain, not the GI tract. Fortunately I am not terribly prone to nausea from phens, but some people are.
 
I have to primarily agree with the above poster. However, I do find that rectal 2C-E (or any substance I've tried so far) does reduce the chance for nausea. Although 2C-E is not a big culprit of that anyway. I guess it depends on how strong your dose is though, and how strongly that affects you. With a high enough dose, things move around enough to make anyone nauseous.
 
I have tried 2C-E rectally before and am aware of the greatly reduced dosage and even steeper dose/response curve. I've tried it up to 11mg this way, which was on par with around 20mg oral I'd say, the nausea was greatly diminished (which is the main reason for preferring rectal to oral in case of 2C-E for me, and well any 2C-x actually). While I agree that nausea isn't too bad when taking 2C-E orally (when compared to, oh let's say 2C-T-7 for example), it is still strong enough to induce vomiting every time I take it, and I hate vomiting and jump at any chance I get to avoid it.
 
On the other hand, 16mg of 2C-E was (for me) equivalent in every way to 250ug of LSD. I've had some of the other 2Cs at 5mg (specifically 2C-D, 2C-I, and 2C-T-7) and all were active at that level. All are also SIGNIFICANTLY less potent than 2C-E...so I would suspect that 5mg of 2C-E will produce noticeable psychedelic effects.

As mentioned earlier, every 2mg of 2C-E can double the intensity...at least this is my experience. You are wise for starting out low. Shulgin mentioned that 10mg is sufficient for a +3 in many people...so there is no need to rush into this one.

My first 2C-E experience, I tried 16mg. Had I not been as experienced with psychedelics as I am, it may have been a very rough ride. Start out much lower than I did.

cornollio said:
yeah... so 5mg isn't going to make you 'trip' it will make you barely feel it. 2ce, while powerful at high doses, is a VERY recreational drug. your gonna need atleast 10 mgs to even see a slight movement of objects. id say 13-14mgs is about the equivalent to a 80mic acid trip. but its a very fun drug IMO.
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I've only taken it rectally thus far and I believe (IIRC) at 15 mgs. I've found it underwhelming. To be honest, none of the phens seems to have too strong an effect on me.

Is it possible that oral dosages will be more rewarding?
 
It is possible that what you have is very poor quality or your rectal administration technique is very poor-

I would imagine 15mg rectal for most people would be an overdose, psychologically and physiologically (manifesting in extreme nausea, puking, tremors, etc)-
 
2C-E, mucous membranes on the other end - I prefer insufflation. To me at least the burn is way overstated - bump it, don't rail it, and it's not that bad.

But I should do an oral dose for comparison sometime...

Insufflation sounds like it is maybe intermediate to oral and rectal. Threshold starts around maybe 10-15 minutes, real manifestations well underway at 30 minutes then after that I usually ignore time for the next four or so hours after which I find myself increasingly losing some of the shimmer of the peak and wishing the stuff would just go away within the next half hour sweetly and quietly like DET does.

My weight is around 195lb/88 kg, definitely soft in the middle, but at 6'1"/185cm I am closer to out of shape than obese...Never been really sure how much of a factor body weight is in psychedelic dosing, feel certain it is not a factor for LSD but for RCs I feel it is at least worth reporting...

I find 8-12 mg by insufflation is about as much as I ever want. Any more and the physical effects become too uncomfortable for me personally. As far as nausea goes, with all psychedelics I always try to eat a good balanced meal at least 5-6 hours or more ahead so the batteries are replenished but the stomach is reasonably clear. I also try to put myself in a position during come ups where puking is convenient and if not a private, at least not a disruptive activity, LOL.

So far with 2C-E I've felt some definite nausea every time, and while I am receptive to it, so far it has not been strong enough to actually happen. Usually what happens is I sit on the tub beside the toilet , waiting for my body to decide which direction it needs to go, and so far every time I have eventually discovered that my fascination with the wall paper is losing it's novelty, and sittng on the tub is not all that comfortable, maybe it;s time to move to another activity or at least a more comfortable chair.

I am, always, a firm believer that if your body really wants to puke, by all means, it should.


As far as phens go it is probably my favorite. The 2C-Xs sort of lack depth, DOXs, just not worth the endurance. My exploratory days were long ago, I just like to still tap in on the rare occasion.

Definitely not a toy. Start low and go slow ...
 
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I have two friends who I have given 2c-e to. The first time was with 12 mgs, and they got nothing. Then 16 mgs, nothing. The next time was with 18mgs in one and 20 in the other, a little but generally nothing. The next time was 22mgs and 20 mgs. still nothing. Now, I must note that this is a batch of 2ce I got about one year ago, and these events are over months and months leading to now with ample breaks between doses. I also must say that me and a friend have taken this batch and got a full +3 with 12-14 mgs.

Whats the deal with that?!?!
 
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