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Phenethylamines [2C-E Subthread] 2C-E Dosage and Methods of Administration

morninggloryseed said:
In PIHKAL, as well as other places, it is well noted that for many, 10mg of 2C-E is plenty for a full trip (+3 experience.)
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User-response seems to vary quite a bit on this substance. I require 15 + mgs for a strong trip, and for many that is too much.
 
I dosed 2mg, and I found out that this one seems like it isn't very forgiving. Interesting buzz. Really hard to explain. Sorta has the amphetamine high feeling but yet totaly different. Feels like I have a halo around my head haha.

This chemical seems to be very beautiful, there is just something about it, even noticeable at threshold levels
 
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first time eh? once with 2-ce i kept re-dosing an entire party because they were not feeling the effects.(not usual - bad aura!?) all orally ingested. and then finally at the +2hr mark everyone broke through and had crazy experiences.

i used to prefer snorting just a whiff of my 2-ce vial to get a nice mild psychedelic buzz... but i think i might try plugging this one with all the hype around it.
 
how much experience do you have with each chemical on its own? The dose-effect curve is exponential with this combo.
I would start with 5mg of each in a pile.
Once you get the feel for the combo, you can increase the dose of each slowly, as 1 extra mg can make the difference between a moderate +2 and a visually stunning +3.
I would also advise you only do this oraly. I was dumb enough to IV 2c-e and it was one of the worst days of my life.
 
Most people recommend if you are after a profound experience to stick with eating it.

My experience with rectal, even, is that it diminishes the profundity of the experience and makes it more recreational. I have reason to believe from sniffing 2CB that 2CE will be even less special snorted than rectal (and way less useful/profound than oral).

I've tried 2CB orally, rectally, and insufflated. Oral was definitely the best.

I will personally stick to oral ingestion for the most profound experience in the future.
 
samadhi, I can assure you that your beliefs about insufflated 2C-E being less special than rectal are incorrect, at least in my experience last night.

Approximately 5mg insufflated was about as potent as 18mg orally and had a much more pronounced euphoria and mind trip than the oral route even. The only downer was that the visuals weren't as pronounced but with how good my body felt, I can't really complain.

I've not had a chemical fuck with my head that hard in a long time. Not since my last time dosing 5 hits of strong LSD. That's definitely something.

We'll see what oral has in store.

But I didn't like 2C-E rectally. It definitely lost a lot of its magic that way.
 
Anyone care to speculate on how the ingestion method has such a profound effect on the nature of the experience?

I haven't tried anything rectally besides lsd, and the only insufflated phen doses I have done are 2c-b on top of oral 2c-b. Did exactly what I expected in that it intensified the trip immensely for a shorter time than the oral dose. Other than a much quicker come up, I can't remember any differences.

Not trying to discount those with more experience, just wondering if anyone has any theories as to why there is so much difference between oral/snorting/rectal ect...

Why does dpt *hurt* (not the nose) when insufflated, but tolerable when IMed?

As far as 2c-e is concerned, my questions are a mute point. I can't imagine it being any better through any route besides oral=D Plus, given the dosage curve, and the relative ferocity of the substance, I not sure if a *bump* is in order.8(
 
Changing the absorption rates can have a profound effect on the subjective feel of the drug. With routes like insufflation and rectal (and of course IV and IM) the peak plasma levels of the drug are much higher (for a shorter amount of time) - ie there is more drug in your blood and subsequently hitting your brain at once than with oral. This effects the comeup and the feel of the peak. For some drugs (like 2CB), this almost entirely chops off the comeup, it is a rocket ride that lasts about 5-10 mins rather than 20-40 mins.

I'm fully convinced that oral is superior for a few drugs that I previously thought rectal was superior for. The 2Cs are one group that this applies to. It is better if one has a chance to resituate oneself during the come-up and transition smoothly into the plateau (to get the most benefit out of the experience).

As far as harm reduction goes, it is much safer to take these chemicals orally rather than insufflate or rectal, since they often contain at least 2-3 percent impurity (from the synthesis) and sometimes contain much greater amounts of impurities (from vendors cutting them). There have been cases of toxic impurities being present in some chemicals where taking them orally would not be a problem (MAO enzymatic processes handle the toxins), while insufflation, rectal, or vaporizing would introduce toxins directly to one's bloodstream (w/o the benefits of first pass metabolism).

I think I will still experiment wth rectal, but for drugs such as AMT, DOC, and DOM, which have VERY long plateaus (and long come-ups).
 
I don't think that rectal AMT will do much for the duration. I could be wrong (my one time trying to do rectal AMT was a mess, I won't go into it but it didn't have a chance to enter my system) but I've found AMT to feel like a completely different substance with alternate routes of entry. AMT HCl snorted lasted longer than oral and so did smoked.

I should note though that the extending of the duration was just the duration of the speedy component.

Insufflation produced a shorter trip but another 6 hours of stimulation than usual.

Smoking freebase felt like like smoking meth but without my heart racing. Very odd feeling.

EDIT: I guess fb has other ideas on rectal AMT. If he's done it, I trust it. Maybe I'll try that next time I do AMT...
 
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I've done 2C-E probably 8 times.

All I can say is: at constant dosage, the effects ranged from non-existant to very pleasant and very obvious.
 
In a week i'm getting 20mg of 2c-e.

This will be the 2nd psychedelic i have ever done, the other one being HBWR seeds.

Is 10mg a good dose to start with? for something not too intense?
 
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alpha-methyl said:
In a week i'm getting 20mg of 2c-e for $10.

This will be the 2nd psychedelic i have ever done, the other one being HBWR seeds.

Is 10mg a good dose to start with? for something not too intense?
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I just tried it for the first time at 10mg. I have to say, I was not disappointed at all. I wasn't tripping exceptionally hard, yet I still had a very deep trip, with insights that can only be rivaled by those of LSD. Just be careful when you take it the next time, do not just jump up from 10 to 20mg, I hear that is quite a leap.
 
alpha-methyl said:
In a week i'm getting 20mg of 2c-e for $10.

This will be the 2nd psychedelic i have ever done, the other one being HBWR seeds.

Is 10mg a good dose to start with? for something not too intense?
Click to expand...
I think that doing a 5mg dose to start off with would be great to see how it affects you at a low dose and then hop straight into a 15 mg about a week later.
A good step up that uses all of the 20 you have/had.

It's how I did it and am waiting to get more to see how a 20 will affect me.
 
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