Yeah to put it blantly, APAP not only damages your liver but kills your intestinal flora as well, not good....on the other hand i can totally understand that you're goingt hru an experiment and don't prolly care,i always advocate for CWE but in your case I dunno if it's necessary if itäs just a one off thing.
Iäm on bupe and skipped my dose for a week first 3 days going CT and then using Kratom and still was feeling lousy totally like shit , anxious even though I was on a shitload of benzos and booze. Sweaty even though therev was a blizzard outside, all dueto taking some compounded hydro/APAPpills tonight and feel like I havenät in a good while, Iäm all itchy already and it's been 50 minutes since dosing.
With 400mg of cimetidine takenban hour before, I got the 10/325 generic norco pills as a gift, just 10 of them, and since I know it's an 'expriment' a 'revival',a once in a blue moon feelgood moment and then back to bupe I didn't mind taking 1625mgof APAP with half abottle of Chilean Malbec.
Very nice nice indeed, good for me liver? nope,chronic drinking is much worse.... taking doses below 3 grams of APAP with alcohol knowing your tolerance to the opioid it'äs combine with once in a bluemoon not so terrible. I know my tolerance and the damage and the despair and how doing a cwe sometimes is out of the question and you NEED your dose,well in that case even though this is a HRforum, Iäd sy that not going above the 3gramsin x24hours will be ok if it's not an usual pattern of usage.
Just to hold off wd's or taper down your dose for a little while and try and not take alcohol with it, if you do lower the opioid dose.
If you donät mind the risks and know the facts and don't care (even though after more than a decade of abuse of all sort of downers my live enzymes showed up like shit and i have a fatty livr, but I blame that on alcohol and benzos more than on opioids all that I was taking that had APAP was codeine and hydrocodone and I was addicted to H and Oxy (generally got 2 pharmaceutical jars of 30 40's and that lasted for a week the most) so i just took APAP to keep wd's at bay and there was no time nor motivation to do an extraction!
Never forthe first dose at least, so as long as thatfirst dose doesnät go above the 3grams per 24 hours and it's not common practice, wheter you have a low to mid tolrance and ar tingit to nod once in a while or if you re using it to keep wd's from harder opioids at bay I can totally understand not performing a CWE on your first dose, b ut itäd prolly be a good idea to perform one once youäe feeling like a million bucks for your next time, actually I will do now, bought some coffee filters specially for it (also drink coffee once a month usually, I hate uppers)....ahhhhhh to bad I only got one good dose left,wellI'm off to enjoy this one.
Chers withyour bittertasting fun ny looking CWEs!!!!)making ratom tea right is harderthanmaking a CWE!)
