1-benzylpiperazine 2hcl

[giantsquid]

whats the difference between this and 1-benzylpiperazine hcl

Is the 2hcl one ok to ingest?

 

[MattPsy]

Yes, you'll just need more of the drug to acheive the same effect. There is extra "weight" taken up by the extra hydrochloride.

 

[giantsquid]

how much more?

 

[MattPsy]

BZP Freebase = 176.26 g/mol-1
HCl=36.46 g/mol-1
BZP*HCl = 212.72 g/mol-1
BZP *2HCl = 249.18 g/mol-1

So, you'll need 1.1714 times more BZP dihydrochloride than monohydrochloride.

 

[BilZ0r]

^ Nice work. Yeah, what he said.

 

[giantsquid]

Thank you very much for helping me out guys

 

[djfriendly]

Why would someone produce BZP with two HCl groups attached instead of one?

 

[Coolio]

Does benzylpiperazine freebase form a 2HCl salt naturally? Is most benzylpiperazine HCl possibly 2HCl? Is equimolar HCl added to BZP freebase to form the 1HCl salt?

 

[BilZ0r]

It will just depend on the pH of the solution it is evaporated from...

 

[hugo24]

If the chemist adds 1 equivalent of HCl,you get the mono HCl salt.If he adds two,you'll get the di-HCl salt.More than two eq's still produces the dihydrochloride but if his skills are lousy and adds 1.2764eq HCl oh well you'll have a mixture.

So making the 2HCl salt is on the safe side for having a homogen and well defined product,though dihydrochlorides are often very hygroscopic and difficult to handle.

Plus,it happens that the monohydrochlorides are crystallising faster/easier and form more stable polymorphs,meaning they are targeted in the first place.

 

[giantsquid]

Yes it is very hydroscopic. but i find all bzp to be hydroscopi to a degree

 

[giantsquid]

ok well I subjected myself to it and it was good stuff so all is well