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2C-E: One Dead and ten hospitalized.

Methamphetamine is in a different schedule (II) and in that schedule it does not include positional isomers.

Ah ok then, didn't realise that. My country's laws have that isomer clause for all the Schedules...

Does sound like it could be a genuine 2CE overdose though if he really was just laying down mephedrone-size lines from a 10g bag of 2CE without any idea how strong the stuff was :(

Also the symptoms of overdose do sound quite similar to that guy who died after snorting 35mg of 2CT7 at once, even if 2CE is 10x less toxic it seems plausible that a similar death could happen if someone snorted 350mg in one line...not impossible from the scenario described.

Probably as with 2CT7 there must be some degree of individual susceptibility involved, i.e. other people have had much more than 35mg of 2CT7 and survived, so just because people have taken 250mg of 2CE and been fine, doesn't mean everyone would be.
 
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JESUS CHRIST!?!? Even people I know that have sold 2C-E "on the street" have never had the need to keep that much 2C-E at once. And in your fucking pocket for fucks sake? I don't even disagree with that 3rd degree murder charge anymore that guy is a fucking retard.

I tend to agree, though I have to assume he was not trying to kill anyone... more likely possibility is he actually thought he was giving them mephedrone or something... but got his baggies mixed up. Still no excuse though.

But I recently accidentally swollowed 800mg of pure Yohimbine (normal STRONG dose 10mg)... intending on taking Sulbutamine (a nootropic)... so that shit does happen even to someone as experienced as me. (btw, after toying with idea of riding it out, when I started to tingle all over, started getting rapidly escalating visual disturbances, and my heart rate shot through the roof, I quickly drove myself to a nearby ER, gave them the bottle, told them what I accidentally did... sat in a wheelchair... and went unconscious... awoke 12 hours later naked in a bed skewered with IVs and heart monitor leads. After about 1hr of waking up felt perfect... except bizarre intense "Rotational Flow" in all visual field except very center that continued for about 24 hrs which was kinda cool actually.)
 
2c-e appears to already be illegal according to the Code of Federal Regulations Section 1308.11.



It is a positional isomer of DOM.

I guess no one really bothered to look hard at the laws we already have.

I'm not a chemist, but one told me that 2C-E would not be a 'positional' isomer or a geometric isomer of DOM. Neither is 2C-G.

A positional isomer of 2C-E would be 4-ethyl, 2,6-dimethoxy-PEA, etc.
 
positional isomer no, compositional isomer technically yes.

DOM and 2CE have the exact same number of C, H, O, and N atoms each.
 
Also, "The Bureau of Criminal Apprehension analyzed the gray powder found in Lamere's pocket and determined it was 8.9 grams of 2C-E. He was arrested on Friday." 8.9 grams were left. That's a lot of 2C-E... I wonder how much he had to start with? 20 grams? That would be about 1 gram snorted per person! I would think that after the first guy railed his line, he'd be in so much pain that no one would want to repeat his action.

Assuming that data is correct, they took a massive dose of 2c-e! 1gram each!!! & given that this chemical is active at 10mgs, 1000mgs is HUGE! I'm surprised they ain't ALL dead. Damned stupid & an unnecesary waste of life.
 
I don't know how you guys make such conclusions about doses. I doubt someone is able to snort 1 gram of 2C-E in a single dose, and I believe that snorting 100-200 mg will immediately result in inability to snort something for a good 5 hours.

Why 20 grams? 10 gram seems more likely.

Also, I don't understand why people can't believe that 2C-E is able to kill someone. Is it really so hard to believe? If 50 people successfully IVed/snorted 100-200 mg, why can't 51st person die from similar dose?
 
^ I concur. With pretty much everything you said.

Having said that, if some dealer really did buy 10g+ of 2C-E he must know how much it costs relative to meph, peevee and other stuff mentioned. It's cheap but not so cheap you'd go dishing out uberlines for the hell of it. The fact it's been described as "grey" so far also suggests this was either not 2C-E at all or was cut with something else.
 
thanks for the legality info there nuke. One interesting thing to see will be if they actually bring the U.S. Attorney's Office in to prosecute the guy. Best I can tell he hasn't broken any laws in MN, unless he knowingly gave them a near lethal dose of whatever it was they took.

Indeed. Analog law territory definitely. If this case isn't a litmus test for it I don't know what is.

3rd degree murder is kind of absurd, any lawyer worth their weight will plea bargain this down to manslaughter at worst. It doesn't sound like this kid had much knowledge about what he was doing.
 
I don't know how you guys make such conclusions about doses. I doubt someone is able to snort 1 gram of 2C-E in a single dose, and I believe that snorting 100-200 mg will immediately result in inability to snort something for a good 5 hours.

Why 20 grams? 10 gram seems more likely.

Also, I don't understand why people can't believe that 2C-E is able to kill someone. Is it really so hard to believe? If 50 people successfully IVed/snorted 100-200 mg, why can't 51st person die from similar dose?

Absolutely. Everyone's natural tolerance is different. One person's overdose is another's ideal dose (usually not this extreme of course).

And the pain would preclude snorting repeatedly. It sounds to me like the dealer skated the first line, probably wincing uncontrollably, holding is hand to his nose in excruciating pain. The birthday boy, drunk, said to himself "fuck it, it can't hurt that bad, I'll show him I'm not a pussy", and proceeded to snort a 200-300mg rail himself. Probably his first time ever using it, and has no idea how his body will react.

It's equally likely adulterated or impure product, or a bad drug combination reaction.
 
^ in one of the articles posted a friend of the decedent's said they had used 2c-e together before, and that it wasn't having the same effect on the night of the incident
 
Question is....





If 2c-E is illegal, will vendors still sell it?



I have seen 5-meo-dmt for sale....

No question. What it comes down to is the question: is the end user willing to take the risks associated with buying scheduled substances through the mail?

This isn't the end of 2C-E by any stretch, but it's about to become a lot more inconvenient and risky for those in the US to acquire it (and probably 2C-I and as many others as they can tack on in short order).

Although the senator's language indicates she's going after the precursors and the whole nine yards, that's just not realistic. Illegal for sale in the US? Most definitely.
 
Indeed. Analog law territory definitely. If this case isn't a litmus test for it I don't know what is.

3rd degree murder is kind of absurd, any lawyer worth their weight will plea bargain this down to manslaughter at worst. It doesn't sound like this kid had much knowledge about what he was doing.

He was obviously in violation of the analogue law, as were everyone who did it... it IS an analogue of schedule I substance(s)... and they all explicitly confirmed their "intent for human use" by using it or providing it for usage... so both arms of the analogue requirement are met. Thus in this case if it was 2c-e... then a schedule I violation DID occur, via the analoge act.

And yea, murder is not what happened, manslaughter at worst... I would pretty much bet he mixed up his stock and THOUGHT he was providing mephedrone or whatever.... why would he waste all the 2c-e that he could have sold in 15mg hits for way way more money... and why would he risk literally killing off his customers?
 
^ in one of the articles posted a friend of the decedent's said they had used 2c-e together before, and that it wasn't having the same effect on the night of the incident

Yes that would explain it. Maybe it was his first time snorting it? Who knows, I'm really speculating too much at this point. I just hope there is some reporting on the toxicology report once available. Whatever killed him needs to be documented. Though the fate of 2C-E is already sealed, we still need to know (at least I do).
 
He was obviously in violation of the analogue law, as were everyone who did it... it IS an analogue of schedule I substance(s)... and they all explicitly confirmed their "intent for human use" by using it or providing it for usage... so both arms of the analogue requirement are met. Thus in this case if it was 2c-e... then a schedule I violation DID occur, via the analoge act.

And yea, murder is not what happened, manslaughter at worst... I would pretty much bet he mixed up his stock and THOUGHT he was providing mephedrone or whatever.... why would he waste all the 2c-e that he could have sold in 15mg hits for way way more money... and why would he risk literally killing off his customers?

You bring up a good point. A mix up of stock seems to be a very likely scenario. From a business standpoint it makes no sense. One of the articles claims the BCA tested and identified it as 2C-E. The greyish description however points to a cathinone or impure product. Maybe in addition to snorting a large dose it was a bad (i.e. toxic) synth? Though I've been told 2C-E is among the easiest PEA's to synth, so a bad batch is unlikely.
 
I'm not a chemist, but one told me that 2C-E would not be a 'positional' isomer or a geometric isomer of DOM. Neither is 2C-G.

A positional isomer of 2C-E would be 4-ethyl, 2,6-dimethoxy-PEA, etc.

It is a positional isomer though. The alpha -methyl that is the difference between DOM and 2C-D? Well you move that methyl on to the para-methyl of 2C-D and wa-lah, that methyl becomes an ethyl: 2C-E
 
It is a positional isomer though. The alpha -methyl that is the difference between DOM and 2C-D? Well you move that methyl on to the para-methyl of 2C-D and wa-lah, that methyl becomes an ethyl: 2C-E

No, the distinguishing factor is that you are 'taking' a carbon from the amine tail, and moving it over to the benzene ring, a completely different part of the molecule. That is not a positional isomer. I don't know what you call it, but it is something else.

Will some of the nomenclature experts chime in on this one?
 
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