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The Big and Dandy NBOMe-2C-C (25C-NBOMe) Thread

ingo_1978 said:
I don't have a milligram scale and was thinking of starting a 0.5mg and was going to dilute it and use a syringe to measure it out and it seemed easier to squirt it up my ass than to snort the fluid
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sounds painful. proportion to use minimal ethanol so say .2 ml is 500 mics. wait for it to evaporate on a baking dish under a heat pad. should recrystalize fine. scrape and snort. a shot of ethanol in the butthole sounds rude and harsh.
 
Addam said:
Yes, acidifying a solution would convert it to a salt that would be water soluble. I'm by no means an expert with NBOMe's, so someone else may have more helpful advice, but I feel this would be preferable to attempting with alcohol.

ADD: Someone else with more experience should elaborate on which liquid would be best for what you're looking for. If it were me, I'd salt it.
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freebase was insoluble in dH2O as expected. added the equivalent of diluted HCl and stirred for a long time. It dissolved. Bioassay with said solution with 120 ug of equivalent freebase intranasally + 60 ugs sublingually was proved active (and beautifully so, if I may unscientifically add)

A very promising compound.
 
hello,

.. i dissolved the freebase in 97% ethanol, works fine.

i first make a "allergic" test with about 80-100µg. a little trippy feeling.
can't say more for firsttime. (no bad feeling or some bad symptoms)
 
sorry for my bad english first :/

.. can someone explain again as I turne the freebase into hcl. get using simple technique.

can i take some little dest. water with a pH value of pH ~ 4-5 and try the
freebase to dissolve in this? then evaporate the water and I have 25C-NBOMe HCL? thank you
 
What method of administration are you planning on using? You might want to just leave it in solution for some methods. But perhaps only salt a portion of what you have, it may have a shorter shelflife as the dissolved cation.

If you evaporate the water it will become more acidic because the volume decreases and the concentration of the muriatic acid rises. If it is only a small volume of water to begin with the amount of acid may not be that significant. I've never tried evaporating everything and don't know if you end up with a little moisture because of the hydrated acid?
And if you start off with too much and concentrate it then snort or plug it may burn. Again: if you start with only a little this may be negligable.

It seems like a simple question and perhaps it is but it puzzles me a little :) I am interested in other peoples comments.
 
thank for first.

I would like to use it sublingual. yes please outher comments.

hmm.. it is not soo easy :\

::EDIT:
.. argg the probleme that you tell, the problem with the water evaporate. i know it from other tests with other substances. you have finaly a (little red) oily substance.
I have not come by myself on this.
 
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Solipsis said:
If you evaporate the water it will become more acidic because the volume decreases and the concentration of the muriatic acid rises. If it is only a small volume of water to begin with the amount of acid may not be that significant. I've never tried evaporating everything and don't know if you end up with a little moisture because of the hydrated acid?
And if you start off with too much and concentrate it then snort or plug it may burn. Again: if you start with only a little this may be negligable.
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HCl is volatile so it should evaporate with the water, probably faster. So the liquid will not become more acidic.

On any case there is no need to lower the pH that much. Use some basic chemistry math! Calculate the molarity of your compound in the water and use the equivalent amount of HCl. In my case I added 5 drops of 0.35 molar HCl for about 12 mg of 25C-NBOMe. The pH dropped to about 6 and was enough to dissolve it all. This pH has no discomfort whatsoever for intranasal or sublingual administration
 
Yes, HCl evaporates at the same rate as the water.
I have prepared hydrochloride salt in this manner, with the slight difference in that I mixed the freebase in sufficient volume of hot IPA for full dissolution, then added 1.5 molar equivalents of 7M HCl solution.
 
MattPsy said:
Yes, HCl evaporates at the same rate as the water.
I have prepared hydrochloride salt in this manner, with the slight difference in that I mixed the freebase in sufficient volume of hot IPA for full dissolution, then added 1.5 molar equivalents of 7M HCl solution.
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Oh yeah I forgot they are azeotropes. Sooo it will not become extremely acidic if you evaporate it, it should pull each other along at a certain point.
 
why dont you just buy blotters? (all those having problems measuring i mean)

i can buy 350mcg blotters so why is it on blotters if it cant be swallowed?

simply for measurement? you would think the place selling it would tell you that you cannot do the obvious thing with the blotter and swallow it?
 
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rainey said:
i can buy 350mcg blotters so why is it on blotters if it cant be swallowed?

simply for measurement?
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Yep... that's pretty much it.

You can re-dissolve the NBOMe out of the blot with a couple of water extractions and insufflate the water solution for full effect. Or you can sublingual the blot directly for reduced effect, or you can swallow it for next to no effect.

rainey said:
you would think the place selling it would tell you that you cannot do the obvious thing with the blotter and swallow it?
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They do. They clearly state "Not For Human Consumption" lol.

But, yeah, I understand what your asking, but that wouldn't be practical: If they told you to not consume it specifically by swallowing, then they would be be suggesting by implication that you can consume it via other ROAs.
 
reformer said:
Yep... that's pretty much it.

You can re-dissolve the NBOMe out of the blot with a couple of water extractions and insufflate the water solution for full effect. Or you can sublingual the blot directly for reduced effect, or you can swallow it for next to no effect.



They do. They clearly state "Not For Human Consumption" lol.

But, yeah, I understand what your asking, but that wouldn't be practical: If they told you to not consume it specifically by swallowing, then they would be be suggesting by implication that you can consume it via other ROAs.
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Thanks for the advice I appreciate it.


The place sending me these has said `yes, with these ones you do(swallow)`


????

Could they have manufactured these in a way that they do work by swallowing? Is that possible/likely.

Have no idea how to do water extraction what if I plugged the blotter would that work?

I`m certainly no novice to a wide variety of rc`s but I dont know anything about chemistry so these extraction techniques etc are beyond me.

Wondering now if i`ve wasted my money lol
 
rainey said:
I dont know anything about chemistry so these extraction techniques etc are beyond me.
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Well, they really shouldn't be beyond you, it would simply be a matter of soaking your blot in the smallest possible drop of water, and then getting all the water out by pressing (using tweezers at at steps). You'd want to "resoak" the blot a second time, which repeats the extraction into a second drop of water. Squeeze out the blot again and insufflate the water drops.

I wouldn't use tap water, but distilled/bottled water is better. Any additives the blot vendor added should only enhance extraction of the NBOMe from the blot into water solution, but this is assuming that your blot is populated with the salt form, not the base form. It's critical to check this point, as if your blot is populated with the base form, the water solution you use will have to be slightly acidic to extract the NBOMe. So, check the form on your blot.
 
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reformer said:
Well, they really shouldn't be beyond you, it would simply be a matter of soaking your blot in the smallest possible drop of water, and then getting all the water out by pressing (using tweezers at at steps). You'd want to "resoak" the blot a second time, which repeats the extraction into a second drop of water. Squeeze out the blot again and insufflate the water drops.
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water is probably not the wisest choice if the blotter has been prepared with the freebase 25C-NBOMe, which is insoluble in water. Ethanol or vodka might be better for extracting the active from the blotter. But then alcohol is not suitable for insuflation, so the usual process of converting it to a salt is in order (see above)
 
Hello guys,

so is it possible to solve freebase 25c-nbome in 96% ethanol and then simply drink it ? is there any material loss? let's say i dissolve 20mg (20.000ug) in 100 ml ethanol, then 1ml of solution = 200 ug ? and simply drink it or add to a drink ?
 
It's possible yeah, but it won't do anything - many people have said it doesn't work orally. You really need to convert it to a salt and insufflate, plug, inject or take it sublingually.
 
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