Here's the results of 3 initial tests with varying dosages of 25C-NBOMe
Subject: male, ~70 kg
All tests with self administered liquid Hydrochloric solution in dH2O
Trial 1
about 120 ug insufflated + 60 ug sublingual.
Took about 30 minutes to start manifesting anything. Some nausea, not too much, though, and some vasoconstriction. Extremities got numb, cold all over the body and some shivering. Real psychedelic mindspace, but not too intense. a comfortable ( if not for the physical symptoms) ++. At T+2.00 back to baseline, and at T+2.30 able to sleep. (I always sleep easily)
Trial 2 ( 1 week after)
~240 ug insufflated.
First signs at T+0.15 Again numbness of the extremities and cold all over. The same nausea but a bit stronger. Much more psychedelic than the initial trial but, unfortunately a difficult trip full of negative thoughts. Mild Mydriasis. This state lasted about 1:00. I can characterize it as a low +++. Some CEVs and OEVs, but due to the low psychic state nothing was pleasant. Able to sleep at T+4.00 after some late hour movie to get out of the bad effects
Trial 3 (2 weeks after last trial)
~420 ug insufflated
First signs at T+0.05. Finger tips insensitized. This caused some anxiety that dissipated gradually through the trip. As a music player, my finger tips are particularly sensitive, and it was disturbing to loose it. Much more cold all over the body than in previous experiences. At T+0.20 it was a full blown psychedelic experience. Strong CEVs with multiplying realities and dreamscapes, OEVs with disentangled and morphing objects. It was deep emotionally but my body felt pretty weak and in the first hour, continuously shivering. Also some persistent light nausea and intestinal discomfort. I was listening to chilling music and let myself be carried with it. I do not know if I could stand a more pop beat. It was very introspective, and music appreciation was considerably increased. For the next 2 hours I was entering successive realities resurfacing to "reality" every 15 minutes or so. A clear and solid +++. Anxiety level dropped during the trip, which was nice, but sensitivity in the finger tips was only regained at T+3.30. Got off the plateau at T+2.45, but was still tripping hard for at least 1.00. This was an overall positive experience, comparable to some of my best 4-AcO-DMT, although lighter on the mind. One is more sharp focused and reality is more easily switched on or off.
At T+ 4.30 could go to sleep, but was difficult, during to strong imagery still on the mind. In the morning, a slight headache, probably due to lack of sleep.
Overall a real positive substance that shows itself better at dosages >300ug. Differently than others I did not find it particularly euphoric. Quite the contrary. I don't imagine myself socializing or in a rave with it. YMMV of course.
Next trial will be 500 ugs, in a month or so.