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The Big & Dandy Methoxetamine(2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone) Thread

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abrad84 said:
What other drugs have you been using in the meantime? Are you on any medications?
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When it comes to strong drugs, just the 2 sessions with 4-MeO-PCP.

I normally take piracetam and centrophenoxine everyday, and modafinil 3-4 times a week, but usually skip that when it's time for dissociatives.


The only difference now is that i haven't used any of the above mentioned nootropics in 2 weeks, since i've been traveling and don't want to explain to customs why i have powders and pills in my luggage. =D But that can't be an explanation. A lot of people claim that piracetam diminishes the effect of ketamine, so i guess it should be the opposite.

It's so frustrating, been looking forward to this for weeks.. Holiday break from school and plenty of mxe at home, good friends coming to stay for some days for some serious exploration of our minds.. :! :X
 
incognition said:
In the beginning of october i enjoyed the fantastic effects of mxe the first time. Since then i've had 2 single dose sessions with 4-MeO-PCP, the last one a few weeks ago.

Two days ago i tried the new batch of mxe, i took 60 mg sublingually, swallowed after 25 minuts. Effects? Nil, null, noll, nothing, nada, klum. It was too late for redosing so i went to bed.

Yesterday i tried again, now i finished 250 mg's in 3 hrs, just to get some treshhold effects, i gave up and went to bed. Woke up this morning in a bad mood.

What the f**k is going on?
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I've had a similar experience with ketamine. I had been dosing 4-MeO-PCP a couple of weeks up to the day I used ketamine. I took huge amounts of ketamine only to experience threshold effects.

I though that I had been scammed and that it was shit ketamine. It's weird to know someone have had a similar experiece with a similar substance.
 
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Up to the day? I haven't touched it in 3 weeks. And that was one single dose..
Mr.Toad said:
I've had a similar experience with ketamine. I had been dosing 4-MeO-PCP a couple of weeks up to the day I used ketamine. I took huge amounts of ketamine only to experience threshold effects.

I though that I had been scammed and that it was shit ketamine. It's weird to know someone have had a similar experiece with a similar substance.
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Ah, ok. Did you do it frequently?

In the name of science i will take my centrophenoxine today, double dose, and try again with mxe tonight. It's something fishy about all this. Centro, piracetam and ketamine are all involved with the same receptors. Maybe i'm a victim of some strange downregulation of.. something.


Mr.Toad said:
No I think there was about a week between the usage of 4-MeO-PCP and Ketamine.

In that week I didn't do any other drugs except drinking some beers.

It's still odd though.
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knockando and JSPete, how often are you currently using methoxetamine? Have you found any evidence of tolerance or withdrawals yet?
Actually I guess this question is open to everyone.
 
Sessionz said:
knockando and JSPete, how often are you currently using methoxetamine? Have you found any evidence of tolerance or withdrawals yet?
Actually I guess this question is open to everyone.
Click to expand...

I received my MXE last wednesday, and have gotten through about 3/4 of a gram. I've had 2 days of not using, last sunday and yesterday up until 22:00

I didn't notice any signs of withdrawal during those two days, nor of tolerance building up. I haven't had any today and feel fine.

It might be too soon for a noticeable tolerance to develop, and I might need to abstain longer for W/D to rear its ugly head, but so far all is well.

I still have over a gram of MXE left as well, so I predict continual use until its all gone.

I would like to mention that during the latter part of yesterday I did develop slight cravings, and really looked forwards to my night time session.
 
Have you found that the opioid effect has diminished at all? I want to play with dosages to get the most of that part of the drug but wonder if continued use would diminish it.
 
forgot to add: how long after a pint should I wait until it's ok to dose MXE to avoid nausea?
 
Leave the pint out completely mate. Alcohol (in any amount) doesn't seem to mix well with MXE. Use on different days to be safe.

I have used quite alot of this compound in the past weeks and have not experienced any noticeable tolerance or withdrawal. I do feel it could be psychologically addictive but then again, so can anything really.

The opioid effect becomes most prominent on the comedown. It's like a nice soft cushion to land in ime.

I sometimes get a mild headache after the effects have worn off. Anyone else experience this?
 
have any of you experienced an increased need to urinate around the days of MXE use?

i find holding in a piss harder to do and some kind of bladder discomfort although mild, still worrying given ketamines ability to leave people with a rubbish bladder
 
Sessionz said:
knockando and JSPete, how often are you currently using methoxetamine? Have you found any evidence of tolerance or withdrawals yet?
Actually I guess this question is open to everyone.
Click to expand...

Once a week for about 12 weeks, then every two or three days for the last two weeks.

No sign of withdrawals. Tolerance - I've gone from 25-35mg doses to 60-70mg doses, I think there's some, but maybe I'm just more used to the lunacy of it. Most likely a combination of a little tolerance and familiarisation.

JSPete's dosing regimen has been a bit more intensive than mine. It took me 12 weeks to get through half a gram. But I was being thrifty as I knew it had to last.

I agree that there are cravings of a sort, but they seem psychological, and are fairly easily ignored.

I can't say I've noticed any major change in the experience over that time - so I assume the effect on opioid receptors is still there. I've not got that much experience with opiates, I smoked Heroin once and not very efficiently. But there is still definitely that wrapped-up warm and cosy feeling.

I haven't felt nausea with alcohol so much as a negative psychological tendency. It feels like the brain just doesn't like the combination, it feels damaging. I would give it two or three hours after a pint and drink some water to rehydrate - but as abrad84 says, best to keep them to different days.

I don't get a headache with this at all - except the next day if I've been stupid and had alcohol too. It seems to amplify the hangover.

No bladder/kidney/urination issues.
 
incognition said:
When it comes to strong drugs, just the 2 sessions with 4-MeO-PCP.

I normally take piracetam and centrophenoxine everyday, and modafinil 3-4 times a week, but usually skip that when it's time for dissociatives.


The only difference now is that i haven't used any of the above mentioned nootropics in 2 weeks, since i've been traveling and don't want to explain to customs why i have powders and pills in my luggage. =D But that can't be an explanation. A lot of people claim that piracetam diminishes the effect of ketamine, so i guess it should be the opposite.

It's so frustrating, been looking forward to this for weeks.. Holiday break from school and plenty of mxe at home, good friends coming to stay for some days for some serious exploration of our minds.. :! :X
Click to expand...

Piracetam works on both NMDA and AMPA, both of which Ket work on. No wonder why ket don't work on you.
 
Has anyone reported combining a low dose of MXE with 6-APB, and if so, what was the response?

If not, can anyone foresee problems mixing these two?
 
knockando said:
I don't think anyone needs to be reckless. You can gradually increase dosages and keep an eye on your self. If you push gently at the boundaries, when they start to give you can take a step back. So to speak; on the macro scale, like. You can't un-dose, obviously, but if 100mg is OK and 110mg is OK but there was that one time where things were uncomfortable, you can wind back and say 100mg seems to be a bit of a limit.
Click to expand...

you write like you know what you are writing about. this post of yours is very useful.
 
I've noticed headaches and a severe dry mouth when waking up from a night on mxe. The sedating effects of mxe seem to have now gone and sort of keep me up but I dont't mind im a night person anyway. Although I don't think of mxe as being 'addictive' it does sort of make me want to push it harder and harder when Im on it, and im not usually the fiendish type (but i can overindulge). Personally I think its the curious aspect of this substance that is doing it, but I don't know. I've given it a rest for two days now as well and have noticed no ill symptoms except from thinking about what daily life would be like on mxe xD
 
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