. I am especially interested in people who have done multiple dissociatives comparing the effects.
Sure, thats a reasonable request

And seeing that there really isn't much info yet on i.m. administration I'll chime in. I have experimented with doses from 10-70 mg, always by i.m administration. After 15 years of often excessive use of various arylcyclohexylamines my NMDA receptors have been pummeled beyond recognition. Ketamine is a crap shoot the last few years, most times 200 mg will send me into a semi-amnesiacal state, and it is only oh so rarely that I can get the experience that wet my tongue all those years ago. PCP is still quite freaky for me, and works a charm, but I've always preferred the higher NMDA to DRI ratio when it comes to my disassociatives. But anyhow, that preamble was just to explain why I probably don't respond the same as most....
10 mg i.m. produces a notable effect within 2 minutes. Probably indistinguishable from 25-30 mg of racemic ketamine at first but it lasts a bit longer and seems less tangential and sedating. Peak effects over within an hour, residual effects lasts 2 hours or so. I've done doses like this quite a bit just for shits and giggles. I really benefit from the lasting antidepressant effect of NMDAR modulators, esp ones that are fun
30 mg i.m produces pronounced disassociation, fun! Listening to the Angels of Light and Michael Gira starts to sounds like a creepy hypersexual dad figure so I take it off and put on BEAK... much better. Comes on fast, but not nearly as immobilized as ketamine, or as dizzy. There is no way I could change the cd or make chai on an equivalent amount of ketamine (this feels similiar to 70ish mg) and already the differences are becoming a clearer. I don't really feel
any opioid effects at any level, but I never have from any of the usual NMDA antagonists (well, errr, besides the obvious ones like methadone, etc). My opioid receptors have been abused as well, but I really feel the mu-agonism is pretty minimal. Obviously a bit more than without the substitution, but nowhere near what a hydroxy group would do. I seem a lot more preoccupied with interpersonal relationships on this substance, rather than the usual hyperspatial hangups. This seems grounded in reality, and produces an emotional lens or window with which to view from. But that window is still located on the observation deck of a either a very high-altitude flying aircraft or a spaceship....back to the hangar in about 2 hours, with some great lasting cheer that persists until sleep.
70 mg starts to get a bit more interesting. I've done this dose a few times and I'm still trying to wrap my head around it compared to its brethren. I guess is feels exactly like it should...it retains that peculiarity that the 3-Methoxy substitution gives to its relatives. This substance does feel like the ketone version of 3-MeO PCE, as it should

, but also has a signature that seems a bit different, more than can be accounted for by the usual SAR musings. At 70 mg it comes on fast enough to not really give you a chance to do much but sit back. A
tad slower than ketamine but still within 2-3 minutes. It retains the window of transference at this level, and I've had some pretty emotionally productive trips. My forays with other arylcyclohexylamines get really preoccupied with this whole alien intelligence/glossolalia/viral-information- infection thing and methoxetamine does none of that. Recently me and my mate did a nighttime time shot (me at 70mg, she at 50) and had a wonderful evening in bed. It was pouring down rain, and our house was shaking in the wind. We started with a beautiful Mick Turner/Tren brothers CD and laid back....I got that smell, that tinny metallic sheen you smell with your ears, and released...I spent a few generations as a small colony of cells circling the stratosphere and rummaging through collective memories, all with the unbiased eye of the observer, but by no means emotionally detached. My hand found my mates under the covers and our collective cell cultures merged, and we went down a dizzying ride of evolutionary biology. I really was amazed with the advent of the central nervous system, the spinal cord in particular was especially gratifying. Our hands kept running over each other and with each curve would come a new phyllum, new orders streaming out...The music at this point had changed to Lift yr Skinny Fists like Antennas to Heaven, appropriately. The swells of the music were beautiful to behold, each crescendo giving birth to petri plates of new life forms....both of us were writhing about in the warm cocoon of our bed, and I had none of the cosmic loneliness I get on ketamine. I often reach a point on high doses of disassociatives where I can use the music to grab onto and pull myself out of the linear progression of a cd playing, and reassemble the notes to form a choose-yr-own adventure made of re-organized bits of reality. This is the point where space/time ceases to work in a linear fashion (bit of a stretch? yeah, i know. It has taken
years to hone this skill

) and for me it is
the special place, the penultimate prize, the be-all-end-all. An amazing intellectual toy....The Glass Bead Game. I can get there with other psychs but disassociatives are the easiest and most forgiving. I was able to
view this place per se but didn't cross over. No worries, I had evolution to attend to!:D When we reached the hominids my heart warmed, and I was suffused with an incredible loving glow. This really made methoxetamite distinct in my mind...it has an incredible empathetic warmth to it, and its not so far out in hyperspace or buried so deep in quantum mechanics as to be unreachable. It is right here, the invisible cord between the spinal cords, and when this conduit is opened and acknowledged it burns with the joy of being recognized. I settled into the joys of being a highland mountain gorilla (was reading Dian Fossey earlier in the day) and me and my mate slowly nuzzled and grunted in our cavern underneath the sheets. Our bed slowly came back down to earth with slower and slower revolutions, and I began to recognize my bedroom and my body again. I kept this powerful love of life on earth, and went to bed swearing to myself I would do "whatever it takes" to get over to Rwanda and lend a hand to my gorilla friends....:D
This experience lasted a little over two hours (plus a few billion years) and I was able to fall into a deep restful sleep three hours after administration. With ketamine (or any other relatives) I would have felt a very strong temptation to re-dose as soon as I was able but strangely I don't really get this from this drug. I felt a little woozier in the morning than I would have after ketamine but nothing near as intense as PCP and such. I kept a a nice after glow the whole following day, and still smile at the thought of this experience.:D
edit- I forgot to add that I have lot more residual stimulation than ketamine after the bulk of the main effects have resided. I had no problem in getting to sleep but even the next day have a pronounced stimulant after effect, possibly due to the increased DRI effects. No crash was noted when these effects finally subsided entirely, possibly 20-24 hrs after the initial dose. Mostly just felt like a nice energetic yet calm afterglow. I could see these effects getting a bit much after repeated redosing but like I said, the compulsion to redose was comparably quite small in me.
Cheers
