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How toxic is Mephedrone?

jac1999 said:
I never take much (500 mg max over 10 hours) but always seem to get a very sore throat and a shit load of really annoying mouth ulcers. Anyone have the same and tips as to how to avoid this???
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Hey jac , I've been in emergency medicine for nineteen yrs now and used to get those mouth ulcers quite frequently until I found a quick fix for them about ten yrs ago. I'm not going to go into any patho about them, I'll just tell you how to get instant relief of pain from most of them and increase resolution of ulcers by 2/3 time. You will need to get a Rx for a potent topical steroid called lidex- its available in several different strengths and preparations- i use the 0.05% solution. Saturate a q tip with the lidex and hold it on every ulcer in your mouth, it will burn sometimes, but it is well worth the pain relief. Initially I apply
It 2-3 times on the first application. Then I apply to affected areas 3-4 times per day as needed afterwards. You will be amazed at the results. Very little risk involved unless you are a diabetic or use it long term daily. Well good luck. Hope it works for you. Quincy
 
Is Methylone considered significantly safer and less toxic?

Compared to Mephedrone, on average for most users, is it any less likely to produce anxiety?
 
Sentience said:
Is Methylone considered significantly safer and less toxic?

Compared to Mephedrone, on average for most users, is it any less likely to produce anxiety?
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Afaik, there have been less reports of severe vasoconstriction and feeling like you have an "exploding heart" etc, but nobody really knows anything solid about either chemicals, all the evidence is anecdotal and based on speculation. It'd be nice if some studies on the long term effects were done, so we'd at least have some idea of the kind of damage we're doing.
 
Wow, reading some things here it seems 500mg is a high dose at times ha...

My area is pretty bad, every second person I know sells it (so they can supply themselves). Each person probably goes through at least 2-3g a night (one of my friends snorted an ounce in 3 nights (upto you if you believe me or not, but thats nearly 10g a night)). Nobody takes any other drugs, it'd take me 5x as long to even get hash/grass. No pills/MDMA, or Charlie hah!
People would do it throughout the week, even if they were working the next day they would stay up snorting and go to work, still awake.

I probably took the least out of everyone, but still at least 500mg a night, I've tended to describe it like ecstacy-lite, and loved it (not as much as pills but, I loved not having a comedown :D).

I've now decided to stop taking it (well, lets see how I manage this weekend...) because after 1-2g I uncontrollably shake, 2 days since I last touched it (quite a bit) and I'm still twitching and feel a bit spaced. Also it feels as though I'm starting to hurt inside (my kidneys mostly).

Do I think I'm addicted to it? In a way probably, in the terms that I would keep taking it even though I'm pretty much flying about the room with the shakes... But no withdrawal symptoms etc. (except for the fiending feeling... but I dont get it that bad :D)

IMO its a great drug, like everything in moderation is great, taking it a lot its still great (but not if you take lots in a single session, the tolerance rockets, no magic in it at all eventually.)
I just worry about how much I've fucked myself up taking so much.

As with all drugs your better off never touching it, but if you do, make sure you can control it... It can very easily get out of hand!
 
i cant find any decent mephedrone anymore. the stuff around here has hit an all time low. did some stuff on saturday night that had zero effect on me. first time ive done any for about 3 months, had a big break from meph and feel much better for it, heart palps, red knuckles, cold hands and paranoia has gone
 
ColtDan said:
if you carry on doing meph theres a good chance you'll get a come down. the come down is fucking horrendous
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I've actually heard the comedown is really bad several times, but even after 3 day binges on it I've always been fine :) maybe I should do more and see ;) kidding! haha.

A friend of mine (pretty much on it every single day, now stopping) said the comedown has been so bad hes thought of self harm/suicide. Lucky hes not the type of person who would actually do it. He knows it would go away...

Dont want to experience it...
 
Is Methylone considered significantly safer and less toxic?
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By far, as the alpha-hydroxylated metabolite is not nearly as potently adrenergic, and people tend to be less likely to binge on m1.

ebola
 
Is Methylone considered significantly safer and less toxic?
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By far, as the beta-hydroxylated metabolite is not nearly as potently adrenergic, and people tend to be less likely to binge on m1.

edit: appending to correct silly error.

ebola
 
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Cambo said:
I've actually heard the comedown is really bad several times, but even after 3 day binges on it I've always been fine :) maybe I should do more and see ;) kidding! haha.

A friend of mine (pretty much on it every single day, now stopping) said the comedown has been so bad hes thought of self harm/suicide. Lucky hes not the type of person who would actually do it. He knows it would go away...

Dont want to experience it...
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after a few months of that useage i reckon you'll experience it. although ive only had the horrible come downs from decent meph, no idea how good your stuff is. Pre-ban was fucking amazing, but havnt tried anything half as good for a long time. yeah the come downs make you suicidal. i lost motivation, had depression, anxiety, paranoid, suicidal for a few days. all that was on my mind was "whats the point in this shit, i cant be assed anymore" and almost quit my job there and then. battled through it, recovered.... then did more meph. got a come down, recovered.... then did more meph. lol. dunno if combining it with alcohol made the come down worse or not. the high was god like though
 
Wow. I would not even consider coming down without some sort of serotonin booster on hand. Even with Prozac it was godawful--2 weeks of extreme fatigue and feeling "blah" emotionally. ...which is why I only indulge every other month now :)
 
In these cases it is best to assume that it is acutely toxic, than to fool oneself into justifying its consumption through anecdotal responses like, "Uh.....I don't feel any brain damage yet"..............

There are qualitatively many superior drugs that least have been "better researched" as to their toxicity. Again, if it is an unknown, expect the worse.

Not sure if i'd rather smoke crack.......maybe IV cocaine of a known purity.....
 
mephedrone is some next shit
i cant believe it blew up as big as it did

it's a pleasure-whore kind of drug
my friend said her dealer's spoon (which was regularly used to spoon out the powder) was all eroded and rusty

so go figure....
 
ColtDan said:
after a few months of that useage i reckon you'll experience it. although ive only had the horrible come downs from decent meph, no idea how good your stuff is. Pre-ban was fucking amazing, but havnt tried anything half as good for a long time. yeah the come downs make you suicidal. i lost motivation, had depression, anxiety, paranoid, suicidal for a few days. all that was on my mind was "whats the point in this shit, i cant be assed anymore" and almost quit my job there and then. battled through it, recovered.... then did more meph. got a come down, recovered.... then did more meph. lol. dunno if combining it with alcohol made the come down worse or not. the high was god like though
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Well I've took it like every weekend since October... Except now.
I never had the chance to try it before it was illegal... Wish I did :( but the stuff I get has been getting better every week (which is the main reason people who are 'off it' usualy get on it to try how good it is haha) apparently its close to pre-ban, but the storys of legal stuff doesn't sound anything like this, never got much of a buzz after three 5-10cm lines...? (When other people outside our group see these lines they almost shit themselves hehe) Although I went outside into the rain which always kills my buzz!

Meph is fucking addictive haha. Fuck that though, I've had friends who have seriously thought about suicide sober in the past, (not anymore, he hates that kinda conversation now) but he's pretty much never off it... Hes got to be a bit of a risk :|
Drinking seems to make everything worse... I still do it regardless haha.
 
Lady Codone said:
Wow. I would not even consider coming down without some sort of serotonin booster on hand. Even with Prozac it was godawful--2 weeks of extreme fatigue and feeling "blah" emotionally. ...which is why I only indulge every other month now :)
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Prozac is an SSRI. SSRIs are well known for taking a while to have an effect (months) and would not be effective for soothing a comedown.
 
They do take a while to work, but not months. Not for me anyway. 2 weeks is about the average it takes me to start feeling it again after quitting for awhile. Maybe I should've said they help re-balance my serotonin levels after the acute comedown or smtg. I forget this is ADD :)
 
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