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The Most Safe Psychedelic

That should be enough evidence that mescaline has its down effects. Mostly the amount needed too feel the desired effects is so high. Aslo it takes a long time to kick in so you may redose thinking your good when really your not. Also, when eating peyote and san pedro, you don't know the exact mg of mescaline you are ingesting. Accidental overdoses happen this way.
 
MagickalKat777 said:
like telling my best friend she didn't meet the system requirements when she tried to offer me water
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Ouch, hope you don't turn into a BSOD the next time you roll.

Physiologically speaking, most of the classical type psychedelics (5-HT2a agonists, such as shrooms, LSD, mescaline, DMT, 4-AcO-DMT, etc.) are very safe, if that's what you're asking.
 
what about ketamine? considering it is a psychedelic as well as a dissociative. just from personal experience at low doses it seems pretty safe compared to RCs
 
Lucid Dream said:
But Mescaline has and can cause death.
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From Ask Erowid: "There have been no verified human deaths from mescaline ever, although K. Trout states that there is one unconfirmed (and unconfirmable) report of a person who died during military experiments with the drug, after receiving a 15 gram dose intravenously (or about 150-200mg/kg)."

Halpern JH, Sherwood AR, Hudson JI, Yurgelun-Todd D, Pope HG Jr. Psychological and cognitive effects of long-term peyote use among Native Americans. Biol Psychiatry 2005, 58:624-31.

"Compared to Navajos with minimal substance use, the peyote group showed no significant deficits on the RMHI or any neuropsychological measures, whereas the former alcoholic group showed significant deficits (p < .05) on every scale of the RMHI and on two neuropsychological measures. Within the peyote group, total lifetime peyote use was not significantly associated with neuropsychological performance."

The classic psychedelics (DMT, psilocybin, mescaline, LSD) have a very good track record in terms of short-term safety and preserving cognition. Changes in visual perception seem to be more common, but rarely lead to significant impairment.
 
From the link provided by Lucid Dream: "We report a case of fatal mescaline intoxication associated with Mallory-Weiss esophageal lacerations. A 32-year-old Native American man with a history of alcoholism ingested peyote tea."

This death is due to vomiting in a chronic alcoholic, and is not directly attributable to Peyote. A stomach virus could have cause the same outcome. Chronic alcoholics can develop esophageal varices (varicose veins in the esophagus) due to liver disease, and these can rupture with prolonged, intense retching. Alcoholics can easily bleed to death or choke and suffocate on blood from a ruptured varix. Also, if it was a Mallory-Weiss tear (also caused by retching, and more common in alcoholics), these are very rarely fatal unless there is a problem with clotting. Unfortunately, alcoholism also leads to deficiencies in clotting factors...

JD42890 said:
what about ketamine? considering it is a psychedelic as well as a dissociative. just from personal experience at low doses it seems pretty safe compared to RCs
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The jury is still out on ketamine neurotoxicity. It seems that prolonged use may lead to lasting deficits.
 
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I just want to bring my concerns to the table, I may be helping someone from making a stupid decision. The amount of mescaline in each botton can range widely, so unless you are working with a pure chemical you don't know how much you ingested. The chemical itself if taken with a scale and measured to your desired dose, you can then use Mescaline responsibly. The question asked was what is the safest psycedelic you can use, and I was just bringing up some concerns about the safety of knowing your dose before consumption.

The way I see it, if you tell someone to ALWAYS use a scale when working with chemicals to eat peyote goes against this. I think thats my main problem with mescaline.
 
Yeah there has never been a single death reported with mescaline that it was confirmed mescaline was the only cause.

ALSO, I haven't heard of someone tripping mescaline and then thinking they could fly and jumping from a building, you don't really "crash" from mescaline, and besides the nausea and vomiting it is easier on the body than any of the others in my opinion.

Its also a lot easier on the mind than shrooms or LSD.

And whoever said 4-AcO-DMT is an idiot. There haven't been enough long term usage studies to find out the safety profile of 4-AcO-DMT. It is not known whether the drug is active on its own or if it has to be turned into 4-HO-DMT to become active, nor is it known whether there are any other metabolites which may be toxic/carcinogenic from its consumption.

And I've seen people (and personally have done this myself) vomit violently from shrooms, go into shudders, and just feel utterly poisoned. As for the LSD suggestion - you never even know if its LSD or not unless you get it right from the chemist.

EDIT: Peyote itself is pretty consistent in alkaloid content. Its fucking with San Pedro that you have no idea. T. Bridgesii is usually much more in the 2% range like peyote though.

And you can do an extraction to get a crude extract of alkaloids if you're so worried about it.

EDIT: Also, 33% of Erowid's LSD trip reports are categorized as bad trips and difficult experiences, 30.9% of Erowid's shroom reports are categorized the same, 22.5% for DMT, while ~10% of mescaline/peyote/cacti fell in those categories...

I stick to my guns - mescaline/cacti.
 
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maybe its the prolonged use thing i know wont happen. at least for me because it is impossible to get around here other than an event. K that is. LSD i can get on a daily basis. its fucked
 
How about this- pretty much every psychedelic has risks. Be informed about the potential risks with whatever substance you choose. It's the best you can do, there's no magic "safe drug".
 
What would you guys say would be the "safest bet" with psychedelic or mind-expanding RC's? Are there are any that have been studied and found to show evidence of relative harmlessness?

Thanks for all the help btw guys!
 
Read through the thread. Its a whopping two pages. There are dissenting opinions. Some feel the psychological profile of the drug can be just as dangerous as the lethality of the drug itself.
 
MagickalKat777 said:
Read through the thread. Its a whopping two pages. There are dissenting opinions. Some feel the psychological profile of the drug can be just as dangerous as the lethality of the drug itself.
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Well yes, i know that. Obviously any Psychedelic has the potential to induce a bad trip and/or frightening psychosis. I'm trying to find out which would be the least dangerous besides that factor.
 
MagickalKat777 said:
If you can get REAL LSD, then technically speaking, LSD has the highest safety of any of them.
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Ah, if only i could 8)

On three out of three occasions LSD has proven to be 100% bunk in my area.

EDIT: As I've heard from experienced comrades, I guess I'm one of those who must wait for Lucy to find me.
 
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