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Bupe Suboxone/Buprenorphine FAQ & Megathread v2; 2010

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jamesBrown said:
I highly doubt that they are actually getting rid of the tablet form of suboxone.....my doctor told me they WERE NOT getting rid of them....that other poster up there said his doc told him they were. WHo knows really?.....all I know is that I see NO evidence that this is going to happen. I have gone to MANY MANY websites trying to find any information at all telling about whether they are getting rid of the tablets or not, but I found NOTHING. NADA. Not one sentence that even hinted at that. I even looked ALL over the suboxone website itself and found no evidence whatsoever that they are going to get rid of the tablets. All it said was that you can have suboxone.com notify you by email when the new film strips are in the pharmacies so you can switch over if you want. It didnt say you were going to HAVE TO switch over. I, for one, do not believe they are going to discontinue the tablets. Atleast they wont discontinue them any time soon.....giving anyone who wishes to keep the tablets, plent of time to "stockpile" them. I allready stockpile them because im given 45 a month but only use about 2-3 a month. You do the math.
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if I'm not needing a little of my suboxone, I always have someone up my ass looking to cop some subs.
 
shanefrommaine said:
I don't get how people do less than even 1mg of soboxone. Seriously it's such a tiny chunk first off, and secondly I vote 1mg at least for a very freshly new starting user. I mean, I just don't think from my POV that's enough of the drug to consider a sesh haha

imo
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When I use less that 1 mg of suboxone it feels more euphoric to me than when I use 1 mg. and when I use 1 mg it feels more euphoric than when I use 2 mg's....and so on.....until you reach about 4mg's....at that point I dont feel ANY euphoria.

Basically, the smaller dose you take, the more euphoria you will yield. It all has to do with leaving more receptors open for bupes metabolite norbupernorphine, which is a full agonist, and can get you high, buzzed, etc....

Also....taking doses of less than 1 mg is very easy....I dont understand why people have such trouble measuring out these doses....

...for example, I take 0.5 mg doses....

....all I do is take one 8 mg pill, crush it up, and divide it into 16 equal piles. This makes each pile 0.5 mg's......very easy. You can also do this to make other sized piles, all you gotta do is change the number of piles you make...quite simple.
 
cballhp said:
As of now it is rumor, but my doctor also told me they where replacing the pill with the strip...I am not worried about it really as I just take mine normally and would like to go on the strip anyways as it dissolves a lot faster. The sample I tried dissolved in about 5 minutes. The pill takes 15-30 minutes for me.
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You know if you simply crush the pill and then put it under your tounge, it should dissolve in less than a minute....atleast thats how it worked for me when I tried it.

Allthough, I still think NO ONE should be taking doses over 4 mg's....meaning you shouldnt even have to worry about dissolving a whole pill under your tounge. I started at 2 mg's/day after IV $xx worth of black tar heroin for 4 years....and it made me feel great. And every time I lowered my dose from 2 mg's, it felt better and better, and now I enjoy my 0.5 mg doses, as they provide me with plenty of euphoria and happiness. I just wished everyone would give low dose suboxone a try.
 
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Ronald MacDonald said:
Captain:
Do you recommend the doxylamine succinate as a substitute for clonidine? I was given clonidine at an outpatient center and had great success with it. Unfortunately, I can't get my hands on them outside and it isn't worth the time (let alone have the time) to go back to the outpatient center.

I've been taking roughly slightly less than 1mg of sub (snorted) on and off for about two and a half-three weeks now. I keep going back and forth between H and sub. :(

I really want to stay away from the H for good, just having problems. I just went through the Ver 8.0 for some confidence.
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Clonidine and doxylamine have different effects, but in terms of as a withdrawal aid, doxylamine will still have some relief. It is not a BP medication, but does have mild sedating properties due to antihistamine and mACH activity.

I found when I first started Suboxone, I switched back and forth from H and Suboxone too, but after a while the Suboxone grew on me and I was happy with Suboxone by itself. It takes time, so don't feel bad if you switch back and forth, just do your best to take Suboxone as much as possible and try to get back to feeling all right about life without full agonist opiates. :)

shanefrommaine said:
I don't get how people do less than even 1mg of soboxone. Seriously it's such a tiny chunk first off, and secondly I vote 1mg at least for a very freshly new starting user. I mean, I just don't think from my POV that's enough of the drug to consider a sesh haha

imo
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Some people would have intense side effects from 1mg, not everyone responds positively to buprenorphine. For someone without any experience with buprenorphine, they should probably start with less than 1mg.

It's easy to water measure out smaller dosages of buprenorphine than it is to try to dissect a small portion of the pill.
 
Captain.......do you have any thoughts on whether or not they are going to replace the suboxone tablets with the film strips completely?

And if you think they are.....how much time do you think we have before the total switch over?
 
jamesBrown said:
Captain.......do you have any thoughts on whether or not they are going to replace the suboxone tablets with the film strips completely?

And if you think they are.....how much time do you think we have before the total switch over?
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They can replace it completely for brand name Suboxone, but I doubt that they are going to discontinue brand name Subutex.

And R&B has absolutely no authority over the generic manufacturers of Subutex, so I am sure that there will be pill formulations of buprenorphine for some time to come.

As for if they will ever fully switch over, who knows? I know that I will be able to go decades without having to worry about this at the rate I am using now, so I'm not stressed out about it personally.
 
Captain.Heroin said:
They can replace it completely for brand name Suboxone, but I doubt that they are going to discontinue brand name Subutex.

And R&B has absolutely no authority over the generic manufacturers of Subutex, so I am sure that there will be pill formulations of buprenorphine for some time to come.

As for if they will ever fully switch over, who knows? I know that I will be able to go decades without having to worry about this at the rate I am using now, so I'm not stressed out about it personally.
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I stockpile my pills like you as i only use 0.5 mg's a day(I know you use MUCH less but whatever) but the problem is I also provide a couple people with daily doses of suboxone so they can get/stay clean from there heroin/oxy addictions.....therfore, its a little harder for me to save my pills. I mean, I still have my own stash, but its not nearly as big as it would be if I didn't provide suboxone for my friends in need.
 
jamesBrown said:
I stockpile my pills like you as i only use 0.5 mg's a day(I know you use MUCH less but whatever) but the problem is I also provide a couple people with daily doses of suboxone so they can get/stay clean from there heroin/oxy addictions.....therfore, its a little harder for me to save my pills. I mean, I still have my own stash, but its not nearly as big as it would be if I didn't provide suboxone for my friends in need.
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I still probably use 0.15 to 0.2 mg per day.

I figure my stockpile of buprenorphine gives me enough time to either find a source for buprenorphine (generics, subutex, buprenex, temegesics, etc), find out how to synthesize it on my own, or move to another country where I can get the tablet formulations.
 
jamesBrown said:
You know if you simply crush the pill and then put it under your tounge, it should dissolve in less than a minute....atleast thats how it worked for me when I tried it.

Allthough, I still think NO ONE should be taking doses over 4 mg's....meaning you shouldnt even have to worry about dissolving a whole pill under your tounge. I started at 2 mg's/day after IV $xx worth of black tar heroin for 4 years....and it made me feel great. And every time I lowered my dose from 2 mg's, it felt better and better, and now I enjoy my 0.5 mg doses, as they provide me with plenty of euphoria and happiness. I just wished everyone would give low dose suboxone a try.
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Yes, I have tried it many times. But it seems to always quickly go down the gutter part and down my throat so it seems I lose a lot of my dose when I do it that way. I currently take 16mg daily and am thinking of going down. I have read on here a lot about the lower you go the more euphoria.

On that subject...has anyone simply just cut their dose significantly? Like from 16mg to 4mg and if you have was there withdrawals and how significant where they? I ask because I pay cash for mine and it is damn expensive so cutting my dose in half would save me $150+ a month.
 
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there is no way they will make the films as the only available prep of bupe. thats totally illegal. you need to have a generic available. its just an evergreening attempt on the pharm cos part. i dounbt the DEA is involved at all.

its a bit different than the OC to OP change. THAT would def have the DEA conspiring with the pharm co. whatever. they will have generic subutex and even generic suboxone. that is why the films are coming out; an attempt to keep charging brand name prices. that is it.
 
So I started on Suboxone last week, everything has been going great as far as cravings and withdrawals go, but my pain has flared back up since I've been on them really bad.

Nothing OTC touches the pain, Tramadol barely takes an edge off the pain at doses in the 150mg+ range.

I did start on the opiates years ago due to chronic pain, along with severe migraines, and I thought going off them would help the pain. While I haven't felt the need to go out and get any, when I'm in severe pain (such as a migraine that lasted 3 1/2 days this week), I was wishing I never got on suboxone, and could just pop a couple percs to relieve the incredibly bad migraine.

What should I tell my Suboxone doctor next time I go back to him regarding pain control while on Suboxone? I'm not asking how to score drugs, but what options are available to someone who really wants off the opiates, but really can't function without them?

Would a Suboxone doctor be open to prescribing low dose Methadone, as it's used for addiction, and pain?
 
methadone and subooxne wouldnt interact with each other well.You'd be going into precipitated w/d every day if you did that. How much sub are you taking a day? At higher doses (4mg-32mg) there's less pain helping properties. With low doses )below 2mg) there's a lot better pain relief with subs.
 
I'm at 4mg per day, though I take 2mg twice daily. Around 12 hours apart.

I wasn't thinking about being on Suboxone and Methadone together at all, but maybe the doctor would swap the Suboxone treatment to Methadone?

I mean, I don't see too much harm in low dose Methadone, the pain alone will have me relapsing if I don't get some relief.
 
True, but keep in mind "low dose methadone" doesnt last too long once tolerance rises with that as well.
 
Yeah, that's true as well.

I'm just not sure what to do, Suboxone keeps my cravings for other opiates down, and took all the withdrawals away, but it does nothing for the pain.

I'm just dissapointed that the Suboxone works so good, but I can't get adequate pain relief while on it.
 
If you try doses between 0.2 and 1 mg's you might get MUCH more analgesic(painkiller) properties out of the suboxone. High doses are NOT meant to kill pain.....they merely prevent withdrawal. It is the low doses of suboxone that actually do the painkilling.....this is why the only pain killing drug composed of bupernorphine was "Tamgesic"...and it came only in 0.2-0.4mg tablets......

"Buprenorphine works better at lower doses because of its metabolite norbuprenorphine, which is a full agonist like heroin or oxy.

norbuprenorphine has a lower binding affinity to your receptors than buprenorphine does just like most other opiates....this is what causes it to kick any other opiates off of your recpectors when you take it....im assuming you know about this allready.

...so, when you take higher doses of buprenorphine(around 4 mg's or more give or take)...this fills all your receptors up with buprenorphine and leaves no room for the metabolite norbuprenorphine to bind.

but when you take small doses of suboxone....all the buprenorphine fills all the receptors it can until there is no more bupe...but since you took a small dose, you still have open receptors with no bupe on them....this allows the norbuprenorphine(full agonist) to bind to those open receptors, causing some euphoria because its a full agonist as compared to bupenorphine which is only a partial agonist.

Everyone is different and everyone must find there "sweet spot", so to speak, concerning the amount of low dose suboxone to take....you want to take a small amount so that you can still have receptors available for the full agonist norbuprenorphine...but not too small so that your leaving receptors unfilled with neither bupe or norbupe.....understand?"

--me, a few weeks ago
 
I just took around .5mg a couple of hours ago, it doesn't feel any different from the usual 2mg at this point.

Does it take time for your body to adjust to the new dosage before you start feeling the effects of the lower dose? Or should I be feeling it already? My usual 2mg dose was about 6am this morning, while my first .5mg dose was about 6pm tonight.

It's also really hard to measure out, as I have 8mg pills, which I have to split into quarters, then split one of those quarters in half just to get 1mg, then split that 1mg peice even further, there doesn't look like there would be much there to absorb?
 
First of all, yes, it does take a little while for your body to adjust to a lower dose, after you come down from taking a higher dose of suboxone. Your body is used to taking in more bupernorphine and consequently you have more bupe built up in your system....so, the higher your dose, and the longer you were on it....the longer it will take for you to adjust to a lower dose of suboxone. I woul give it atleast 4-5 days to see if your body is adjusting well.

Also, I don't understand the problem with measuring out the correct amount of suboxone? If you want to take 0.5 mg doses than all you have to do is take one 8 mg suboxone tablet and crush it up. Then, divide that powder into 16 equal piles....this makes each pile 0.5 mg's.....its quite easy, I do it all the time. You can adjust the amount in each pile by changing the number of piles you divide it into.
 
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