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Bupe Suboxone/Buprenorphine FAQ & Megathread v2; 2010

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interesting, well maybe ill do a little personal experiment tomorrow and try doing 30 mg of Opana er instead of the usual 20 to see how well this blocker really works!8o
 
shanefrommaine said:
I just went to my Suboxone doctor today. It's official. The United States is going to 100% switch from the pills to the strips. He said they are just waiting for the pharmacies to sell out of the subs (much like the oc to op switch) then the strips will be the only thing you get. My doctor also said that each strip will be individually wrapped in a serial numbered package that can be traced back to the patient whom's prescription it is... to try and stop the illegal sale of Suboxone. Finally, my doctor said that every Suboxone prescribing doctor will require each patient to bring in to their appointments, every single serial numbered package... again to try and stop the flow of Suboxone.
Click to expand...

I was told a completely different story from my sub doc a couple days ago....he said that the representative who came to his practice to hand out samples of the new strips said that BOTH the pill and the strips were going to be available. Something to do with the fact that some people may not respond well to/or simply not like the new strip formulation. Im not sure, but I find it hard to believe they will completely stop the production of suboxone in the pill form. It just doesnt make sense to me.

Anyway, if you could show a source stating that they truly are getting rid of suboxone pills, please post it...otherwise im gonna hold onto my hope that my precious pills wont be taken away from me.
 
adder said:
No matter if this works or not, it's a good reason for the elimination time to get shorter. Norbuprenorphine normally shouldn't play any major role in buprenorphine's efficacy as 2/3 of taken drug is eliminated unchanged with faeces. Anyway, if you induce some enzyme to produce more of a certain metabolite, you must also know that both buprenorphine and norbuprenorphine undergo 3-O-glucuronidation. I'd really try a full agonist at mu & delta and a partial agonist at kappa. And I'm actually quite mad at myself because by simple N-dealkylation I could get norbuprenorphine and I would know how different it is because the guy there is wrong about how norbuprenorphine weakly passes through BBB (source).

Doing it this way, I doubt that you would even get enough norbuprenorphine so it "gets through" as its effects are blocked by buprenorphine (another great proof that buprenorphine really is a drug for maintenance). Norbuprenorphine given alone would probably produce different effects (and strong as such oripavine analogs with one more ring and side-chain at C7 have a very interesing SAR). Anyway drugs with secondary amine interact with receptors worse than those with tertiary amine (like morphine vs. normorphine), so binding affinity of buprenorphine must be higher than norbuprenorphine's.
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very interesting adder thanks for sharing that
 
kelvanE said:
Quote:
Originally Posted by shanefrommaine
I just went to my Suboxone doctor today. It's official. The United States is going to 100% switch from the pills to the strips. He said they are just waiting for the pharmacies to sell out of the subs (much like the oc to op switch) then the strips will be the only thing you get. My doctor also said that each strip will be individually wrapped in a serial numbered package that can be traced back to the patient whom's prescription it is... to try and stop the illegal sale of Suboxone. Finally, my doctor said that every Suboxone prescribing doctor will require each patient to bring in to their appointments, every single serial numbered package... again to try and stop the flow of Suboxone.
Click to expand...

Ill believe it when I see it that doesnt even sound all that possible. I cant find any announcement on the net that says this doctors are idiots dont believe everything they say.
 
hay-o everyone... in case anyone was wondering i didn't get those hellish withdrawals..i felt a little cold sweat and anxiety at first but then i had some wine and half a klonopin and i ended up being fine.
speaking of which, i IV the subs and sometimes snort them. i have some klonopin, i know, not the greatest benzo but what the hell. i have put together that mixing them in moderation should be okay so now all i am wondering is:
preferred methods? will i get high?
if i IV it how much should i mix, or should i do them together IV... i don't know much about the benzo stuff as i am mostly just an opiate addict.
 
crimsonjunk said:
Ill believe it when I see it that doesnt even sound all that possible. I cant find any announcement on the net that says this doctors are idiots dont believe everything they say.
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a. that's ignorant to drop a blanket statement that doctors are idiots
b. google 'suboxone films'

I'm just stating what I was told by a doctor, so I believe the credibility personally.
 
pinsinmyneedles said:
hay-o everyone... in case anyone was wondering i didn't get those hellish withdrawals..i felt a little cold sweat and anxiety at first but then i had some wine and half a klonopin and i ended up being fine.
speaking of which, i IV the subs and sometimes snort them. i have some klonopin, i know, not the greatest benzo but what the hell. i have put together that mixing them in moderation should be okay so now all i am wondering is:
preferred methods? will i get high?
if i IV it how much should i mix, or should i do them together IV... i don't know much about the benzo stuff as i am mostly just an opiate addict.
Click to expand...

You should not IV clonazepam because it is poorly water soluble.
 
tapering subutex

hi everyone.first of all i apologise if im repeating myself since i have a post that is somehow related to this one,only the question i have to make here is different despite the same problem.i went to a sub doc and he put me on a long tapering starting at 4mg for 2 months more or less,after that i guess he ll put me on 2mg and so on.
my question is:is there a faster way to taper this hellish pills down without having bad w/d,im at work and have no time off.
i researched and saw a few charts on how to do it,does anyone knows if they work,or one that works,can u describe it to me,ill be so very thankfull as i have not that much money to spent on subs all that time the doc wants me to.
stay safe everyone,thanx in advance and sorry for the similar post but it s out of desperation,i need this off me,i need to be me..
 
Clonazepam may take some time to kick in so if you're going to i.v. buprenorphine, you might consider putting crushed pills of clonazepam under your tongue. You should feel the effects within 30 minutes unless you're addicted to it. I take a set amount of it once a day (though my doctor told me to spare it and thinks I do, for me it doesn't work too good during the day when I need it the most) and I could even lower my 6mg dose by 2mg for a few days or take 2mg more and it doesn't change anything. As I said to myself "nvm maintenance" but I don't really plan to go back to needles, the only way I can get some more euphoria than sedation from methadone is to crack pills and put them under my tongue 30 minutes after taking methadone.

And I just realized I must switch to something short-acting but as strong as morphine or stronger with good oral BA or at least I must get a solution of something to i.m. it before I can try to maintain on buprenorphine... I've tried to survive the beginning of methadone w/d today to i.v. buprenorphine but knowing I would have to shoot some nice amount of 3-MF to break through I didn't want to risk precipitated w/d as methadone w/d is really taking on power slowly and you already feel shitty, your mind goes crazy, I'm cold constantly (but I've got problems with hypothyroidism so I'm lost, I take levothyroxine but still I don't feel my memory works like it did before it happened)... Anyway, I know it's still not this. Once I spent 4 days without methadone being addicted to it and it was a nightmare. Every w/d from any short-acting opioid is better for me than methadone w/d.
 
Tapering won't be fun but it will work.

If you need to be in WD the least amount for work, then use as much Suboxone as you find necessary, in 2mg doses throughout the day. If you need to take up to 8mg the first few days, that is OK. By the 4th-5th day you should be down to 4mg or 6mg per day.

By the end of the first week you can try for 2mg to 4mg per day, and you can sustain that for another week or two while you are getting used to sobriety again.

The key to a successful taper, especially with buprenorphine, is to go as low as possible with it. Once you get to 2mg per day, try using less than that (1mg or less ideally) before jumping off completely.

I'm also going to merge this into the Suboxone mega thread. :) Good luck!
 
shanefrommaine said:
I just went to my Suboxone doctor today. It's official. The United States is going to 100% switch from the pills to the strips. He said they are just waiting for the pharmacies to sell out of the subs (much like the oc to op switch) then the strips will be the only thing you get. My doctor also said that each strip will be individually wrapped in a serial numbered package that can be traced back to the patient whom's prescription it is... to try and stop the illegal sale of Suboxone. Finally, my doctor said that every Suboxone prescribing doctor will require each patient to bring in to their appointments, every single serial numbered package... again to try and stop the flow of Suboxone.
Click to expand...

Them adding a serial number on them sounds like something they would do. Someone sells a few strips to another and they go and get pulled over and found with them then they just check a database them bamn they got the supplier.

On the other hand it is a complete waste of time and manpower and even the ink used to print it. People will just open the package, take strip out and sell it but keep the package.
 
SubDude said:
^ sounds like a good time to tell your subs doc that your dose isn't holding you. Get up as high as possible and stockpile.
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One thing not really mentioned is that Subutex will not be made into the strip, so may be a good time for those who prefer the tablet for various reasons to switch to Tex. Maybe start developing brutal headaches because of the nal in sub ;)
 
cballhp said:
Them adding a serial number on them sounds like something they would do. Someone sells a few strips to another and they go and get pulled over and found with them then they just check a database them bamn they got the supplier.

On the other hand it is a complete waste of time and manpower and even the ink used to print it. People will just open the package, take strip out and sell it but keep the package.
Click to expand...

Absolutely what I was saying to my friend who picked me up from my appointment.
 
Captain:
Do you recommend the doxylamine succinate as a substitute for clonidine? I was given clonidine at an outpatient center and had great success with it. Unfortunately, I can't get my hands on them outside and it isn't worth the time (let alone have the time) to go back to the outpatient center.

I've been taking roughly slightly less than 1mg of sub (snorted) on and off for about two and a half-three weeks now. I keep going back and forth between H and sub. :(

I really want to stay away from the H for good, just having problems. I just went through the Ver 8.0 for some confidence.
 
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SubDude said:
^ sounds like a good time to tell your subs doc that your dose isn't holding you. Get up as high as possible and stockpile.
Click to expand...

I highly doubt that they are actually getting rid of the tablet form of suboxone.....my doctor told me they WERE NOT getting rid of them....that other poster up there said his doc told him they were. WHo knows really?.....all I know is that I see NO evidence that this is going to happen. I have gone to MANY MANY websites trying to find any information at all telling about whether they are getting rid of the tablets or not, but I found NOTHING. NADA. Not one sentence that even hinted at that. I even looked ALL over the suboxone website itself and found no evidence whatsoever that they are going to get rid of the tablets. All it said was that you can have suboxone.com notify you by email when the new film strips are in the pharmacies so you can switch over if you want. It didnt say you were going to HAVE TO switch over. I, for one, do not believe they are going to discontinue the tablets. Atleast they wont discontinue them any time soon.....giving anyone who wishes to keep the tablets, plent of time to "stockpile" them. I allready stockpile them because im given 45 a month but only use about 2-3 a month. You do the math.
 
I don't get how people do less than even 1mg of soboxone. Seriously it's such a tiny chunk first off, and secondly I vote 1mg at least for a very freshly new starting user. I mean, I just don't think from my POV that's enough of the drug to consider a sesh haha

imo
 
jamesBrown said:
I highly doubt that they are actually getting rid of the tablet form of suboxone.....my doctor told me they WERE NOT getting rid of them....that other poster up there said his doc told him they were. WHo knows really?.....all I know is that I see NO evidence that this is going to happen. I have gone to MANY MANY websites trying to find any information at all telling about whether they are getting rid of the tablets or not, but I found NOTHING. NADA. Not one sentence that even hinted at that. I even looked ALL over the suboxone website itself and found no evidence whatsoever that they are going to get rid of the tablets. All it said was that you can have suboxone.com notify you by email when the new film strips are in the pharmacies so you can switch over if you want. It didnt say you were going to HAVE TO switch over. I, for one, do not believe they are going to discontinue the tablets. Atleast they wont discontinue them any time soon.....giving anyone who wishes to keep the tablets, plent of time to "stockpile" them. I allready stockpile them because im given 45 a month but only use about 2-3 a month. You do the math.
Click to expand...

As of now it is rumor, but my doctor also told me they where replacing the pill with the strip...I am not worried about it really as I just take mine normally and would like to go on the strip anyways as it dissolves a lot faster. The sample I tried dissolved in about 5 minutes. The pill takes 15-30 minutes for me.
 
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