B&D Plugging Thread - there's another one in OD too. Means rectal dosing - making a solution with the drug of choice (some drugs are more suited than others) and using an oral syringe to put it where the sun don't shine. Usually has a much higher bioavailability - only need around half your usual dose with many drugs - you come up within minutes and has a great rush not a million miles from an IV rush even. Depends on the drug how much better a method it is than others - MSContins are a good one to plug, for example, cos they have terrible BA nasally and orally and are a pain in the arse
D) and very dangerous to IV.
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) of wine or sherry and died. People greatly underestimate the BA and strength of rectal dosing but it's not the best option for everything. Most things maybe, in my experience, but not quite everything.